lysosomal membrane Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. (Gene Ontology, GO_0005765)
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Genes

232 proteins co-occuring with the lysosomal membrane cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
LAMP1 lysosomal-associated membrane protein 1 2.28299
LAMP2 lysosomal-associated membrane protein 2 2.23145
ACPP acid phosphatase, prostate 1.87865
CTSD cathepsin D 1.8266
CTSS cathepsin S 1.60476
CTSB cathepsin B 1.5514
GUSB glucuronidase, beta 1.51976
ACP2 acid phosphatase 2, lysosomal 1.40578
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 1.32492
CTNS cystinosin, lysosomal cystine transporter 1.234
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 1.16696
CLN3 ceroid-lipofuscinosis, neuronal 3 1.16133
CD63 CD63 molecule 1.14392
APOL1 apolipoprotein L, 1 1.08476
TMEM192 transmembrane protein 192 1.08019
GLB1 galactosidase, beta 1 1.07308
SCARB2 scavenger receptor class B, member 2 1.05993
CTSL cathepsin L 0.93785
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.900426
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.899036
LMBRD1 LMBR1 domain containing 1 0.867206
GBA glucosidase, beta, acid 0.860311
RILP Rab interacting lysosomal protein 0.849287
SIDT2 SID1 transmembrane family, member 2 0.83322
MCOLN1 mucolipin 1 0.828171
M6PR mannose-6-phosphate receptor (cation dependent) 0.827254
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.820829
CD164 CD164 molecule, sialomucin 0.816699
TFEB transcription factor EB 0.813487
CAT catalase 0.793313
NPC1 Niemann-Pick disease, type C1 0.785986
GLMP glycosylated lysosomal membrane protein 0.773645
GSR glutathione reductase 0.756345
HSPA1B heat shock 70kDa protein 1B 0.702626
HSPA4 heat shock 70kDa protein 4 0.686827
RRAGC Ras-related GTP binding C 0.675934
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.673328
DNAH8 dynein, axonemal, heavy chain 8 0.647003
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 0.638861
HEXDC hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing 0.635868
ATP13A2 ATPase type 13A2 0.630745
BAX BCL2-associated X protein 0.626909
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 0.604862
FTH1 ferritin, heavy polypeptide 1 0.601487
IGF2R insulin-like growth factor 2 receptor 0.594753
NAGA N-acetylgalactosaminidase, alpha- 0.589295
VAMP7 vesicle-associated membrane protein 7 0.573411
ENGASE endo-beta-N-acetylglucosaminidase 0.569664
PGRMC1 progesterone receptor membrane component 1 0.567585
HSPA1A heat shock 70kDa protein 1A 0.563432
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 0.544823
GM2A GM2 ganglioside activator 0.54194
PLA2G1B phospholipase A2, group IB (pancreas) 0.54194
NEU2 sialidase 2 (cytosolic sialidase) 0.533309
LAMP3 lysosomal-associated membrane protein 3 0.531668
LYZ lysozyme 0.531668
MFSD8 major facilitator superfamily domain containing 8 0.527979
SBF2 SET binding factor 2 0.52716
GPR137B G protein-coupled receptor 137B 0.517756
LAMP5 lysosomal-associated membrane protein family, member 5 0.508383
ALPPL2 alkaline phosphatase, placental-like 2 0.507163
ALPL alkaline phosphatase, liver/bone/kidney 0.50635
ALPP alkaline phosphatase, placental 0.505944
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.504318
HSPA8 heat shock 70kDa protein 8 0.492561
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 0.491348
FTL ferritin, light polypeptide 0.490539
GSTA3 glutathione S-transferase alpha 3 0.488519
GSTA4 glutathione S-transferase alpha 4 0.486904
GSTA2 glutathione S-transferase alpha 2 0.486904
GSTA1 glutathione S-transferase alpha 1 0.484483
HPR haptoglobin-related protein 0.480453
DNASE2 deoxyribonuclease II, lysosomal 0.48005
NPC2 Niemann-Pick disease, type C2 0.479245
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.475223
EEA1 early endosome antigen 1 0.474822
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 0.472813
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 0.472011
CYB561A3 cytochrome b561 family, member A3 0.462398
EDA ectodysplasin A 0.458803
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 0.457208
RRAGD Ras-related GTP binding D 0.454816
LMBR1L limb development membrane protein 1-like 0.451631
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 0.45004
PACS2 phosphofurin acidic cluster sorting protein 2 0.45004
GAA glucosidase, alpha; acid 0.444482
TP53 tumor protein p53 0.439333
TFRC transferrin receptor 0.416902
VTI1B vesicle transport through interaction with t-SNAREs 1B 0.41612
MT2A metallothionein 2A 0.406361
AP3B2 adaptor-related protein complex 3, beta 2 subunit 0.405582
IRGM immunity-related GTPase family, M 0.405582
ACHE acetylcholinesterase (Yt blood group) 0.402859
GSTM2 glutathione S-transferase mu 2 (muscle) 0.400916
ALB albumin 0.400916
SCP2 sterol carrier protein 2 0.399751
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.396648
ALDOC aldolase C, fructose-bisphosphate 0.39626
ALDOB aldolase B, fructose-bisphosphate 0.39471
TFDP1 transcription factor Dp-1 0.385436
NEU3 sialidase 3 (membrane sialidase) 0.378122
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 0.375434
SYT7 synaptotagmin VII 0.362804
SOD2 superoxide dismutase 2, mitochondrial 0.360515
GPX5 glutathione peroxidase 5 0.357467
TPD52 tumor protein D52 0.354802
HPS1 Hermansky-Pudlak syndrome 1 0.352901
CTSE cathepsin E 0.352901
GPX4 glutathione peroxidase 4 0.351762
TCTA T-cell leukemia translocation altered 0.351002
KIF25 kinesin family member 25 0.347208
GPX1 glutathione peroxidase 1 0.341151
SCGB1D1 secretoglobin, family 1D, member 1 0.338506
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 0.334356
NSDHL NAD(P) dependent steroid dehydrogenase-like 0.333225
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.332848
NSF N-ethylmaleimide-sensitive factor 0.332848
IDUA iduronidase, alpha-L- 0.332095
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.330213
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) 0.324576
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) 0.324576
CALCOCO2 calcium binding and coiled-coil domain 2 0.3227
DNAH3 dynein, axonemal, heavy chain 3 0.320451
RNF19B ring finger protein 19B 0.319702
PFKM phosphofructokinase, muscle 0.31783
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 0.31783
TPP1 tripeptidyl peptidase I 0.316708
ANXA5 annexin A5 0.312224
SVIP small VCP/p97-interacting protein 0.310732
MT3 metallothionein 3 0.309613
TPCN2 two pore segment channel 2 0.309613
MTMR2 myotubularin related protein 2 0.308122
RAB34 RAB34, member RAS oncogene family 0.307377
TPCN1 two pore segment channel 1 0.303655
LALBA lactalbumin, alpha- 0.287352
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.286245
SKAP2 src kinase associated phosphoprotein 2 0.269701
CPNE1 copine I 0.268237
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 0.266408
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.265677
CLN5 ceroid-lipofuscinosis, neuronal 5 0.265311
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 0.264946
APEH acylaminoacyl-peptide hydrolase 0.26166
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 0.257652
INS insulin 0.256197
SLC38A2 solute carrier family 38, member 2 0.255107
ELANE elastase, neutrophil expressed 0.253653
RNPEP arginyl aminopeptidase (aminopeptidase B) 0.252564
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.250026
SLC29A4 solute carrier family 29 (equilibrative nucleoside transporter), member 4 0.249664
STX7 syntaxin 7 0.24894
NVL nuclear VCP-like 0.248578
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 0.248397
BCHE butyrylcholinesterase 0.245685
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.238837
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.238119
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.237042
CEL carboxyl ester lipase 0.235249
PSIP1 PC4 and SFRS1 interacting protein 1 0.234174
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) 0.232029
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 0.230958
CTSA cathepsin A 0.229532
TG thyroglobulin 0.22279
RHEB Ras homolog enriched in brain 0.221378
ARL8B ADP-ribosylation factor-like 8B 0.218563
CTSH cathepsin H 0.217511
CD4 CD4 molecule 0.215761
PGPEP1 pyroglutamyl-peptidase I 0.212627
PRDX6 peroxiredoxin 6 0.211933
CIDEB cell death-inducing DFFA-like effector b 0.210894
PRF1 perforin 1 (pore forming protein) 0.208825
PRTN3 proteinase 3 0.206082
SCAMP3 secretory carrier membrane protein 3 0.203699
ARL5B ADP-ribosylation factor-like 5B 0.202009
PPT1 palmitoyl-protein thioesterase 1 0.201672
MPO myeloperoxidase 0.199659
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 0.198658
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.194045
SIAE sialic acid acetylesterase 0.193719
HPS6 Hermansky-Pudlak syndrome 6 0.192746
DIRC2 disrupted in renal carcinoma 2 0.18859
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.186397
TM4SF5 transmembrane 4 L six family member 5 0.183328
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 0.182122
ZFYVE26 zinc finger, FYVE domain containing 26 0.180634
CARD17 caspase recruitment domain family, member 17 0.180339
CTSC cathepsin C 0.180045
NAGLU N-acetylglucosaminidase, alpha 0.177154
PKLR pyruvate kinase, liver and RBC 0.17687
CTRB1 chymotrypsinogen B1 0.174361
LAPTM5 lysosomal protein transmembrane 5 0.173814
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.172201
PAOX polyamine oxidase (exo-N4-amino) 0.171673
ALDOA aldolase A, fructose-bisphosphate 0.168847
G6PC glucose-6-phosphatase, catalytic subunit 0.168598
TYR tyrosinase 0.168101
MIR31 microRNA 31 0.165231
SYTL1 synaptotagmin-like 1 0.164599
CTSG cathepsin G 0.159806
RRAGB Ras-related GTP binding B 0.159074
NT5E 5'-nucleotidase, ecto (CD73) 0.157039
TP63 tumor protein p63 0.157039
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.156688
AZU1 azurocidin 1 0.146141
GPR143 G protein-coupled receptor 143 0.141558
CD1B CD1b molecule 0.140143
STOM stomatin 0.140111
SYT3 synaptotagmin III 0.139706
PLD1 phospholipase D1, phosphatidylcholine-specific 0.139271
DYSF dysferlin 0.139125
BPI bactericidal/permeability-increasing protein 0.139069
FLOT1 flotillin 1 0.138896
PLD2 phospholipase D2 0.138505
PRKD3 protein kinase D3 0.137672
SH2D3A SH2 domain containing 3A 0.13695
RAB27A RAB27A, member RAS oncogene family 0.136
EGOT eosinophil granule ontogeny transcript (non-protein coding) 0.135984
EPCAM epithelial cell adhesion molecule 0.135244
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.134341
TPM3 tropomyosin 3 0.133141
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 0.132742
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.132269
PI3 peptidase inhibitor 3, skin-derived 0.131763
SYT1 synaptotagmin I 0.13021
PFN4 profilin family, member 4 0.129728
ARF6 ADP-ribosylation factor 6 0.129479
PFN2 profilin 2 0.129179
PFN1 profilin 1 0.128474
CD68 CD68 molecule 0.128213
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.126564
CSN1S1 casein alpha s1 0.123988
MAPRE1 microtubule-associated protein, RP/EB family, member 1 0.123288