lymph node disease Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:9942
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Genes

113 genes associated with the disease lymph node disease in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
ITPKC inositol-trisphosphate 3-kinase C 1.68078
BLK BLK proto-oncogene, Src family tyrosine kinase 1.63599
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.5865
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 1.43347
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 1.39396
CENPU centromere protein U 1.37327
SLC35F5 solute carrier family 35, member F5 1.32771
IRF8 interferon regulatory factor 8 1.31031
IL1RAP interleukin 1 receptor accessory protein 1.27311
TECRL trans-2,3-enoyl-CoA reductase-like 1.26953
BUD31 BUD31 homolog (S. cerevisiae) 1.26075
ZSCAN25 zinc finger and SCAN domain containing 25 1.26075
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 1.26075
MED30 mediator complex subunit 30 1.24194
HLA-DRA major histocompatibility complex, class II, DR alpha 1.23853
LDLRAD3 low density lipoprotein receptor class A domain containing 3 1.22454
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 1.19631
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 1.19386
CADPS Ca++-dependent secretion activator 1.179
DNM3 dynamin 3 1.17489
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 1.16261
ZFHX3 zinc finger homeobox 3 1.14463
PELI1 pellino E3 ubiquitin protein ligase 1 1.14463
SLC39A13 solute carrier family 39 (zinc transporter), member 13 1.14222
GCOM1 GRINL1A complex locus 1 1.13453
CLEC3A C-type lectin domain family 3, member A 1.13453
ZNF655 zinc finger protein 655 1.12969
PTCD1 pentatricopeptide repeat domain 1 1.12969
TFCP2 transcription factor CP2 1.12405
TMEM233 transmembrane protein 233 1.11582
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 1.11517
ZNF717 zinc finger protein 717 1.11453
MLIP muscular LMNA-interacting protein 1.11384
CD40 CD40 molecule, TNF receptor superfamily member 5 1.11014
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 1.08665
RIMS2 regulating synaptic membrane exocytosis 2 1.08533
KCNK3 potassium channel, two pore domain subfamily K, member 3 1.08054
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 1.05244
ERC2 ELKS/RAB6-interacting/CAST family member 2 1.04717
NCK2 NCK adaptor protein 2 1.03718
TLL1 tolloid-like 1 1.01598
DEC1 deleted in esophageal cancer 1 1.01535
VIL1 villin 1 1.01535
RAB4B RAB4B, member RAS oncogene family 1.01328
FHIT fragile histidine triad 1.01328
SMC5 structural maintenance of chromosomes 5 1.01185
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 1.00965
FSTL4 follistatin-like 4 1.0073
BTBD1 BTB (POZ) domain containing 1 1.00407
LOC100130301 0.988367
HLA-DOB major histocompatibility complex, class II, DO beta 0.980012
SNRPA small nuclear ribonucleoprotein polypeptide A 0.975198
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.973595
SHC4 SHC (Src homology 2 domain containing) family, member 4 0.972876
LOC100287329 uncharacterized LOC100287329 0.972589
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L 0.971169
PXDNL peroxidasin-like 0.970607
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like 0.966037
ZNF536 zinc finger protein 536 0.965651
CLCN3 chloride channel, voltage-sensitive 3 0.963371
LOC285692 uncharacterized LOC285692 0.962871
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 0.95993
EBF2 early B-cell factor 2 0.959809
PROKR2 prokineticin receptor 2 0.922781
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.885884
ROR2 receptor tyrosine kinase-like orphan receptor 2 0.879151
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.874542
RBP2 retinol binding protein 2, cellular 0.869616
COL4A2 collagen, type IV, alpha 2 0.862937
NUMBL numb homolog (Drosophila)-like 0.855811
C6ORF10 chromosome 6 open reading frame 10 0.848917
PDGFD platelet derived growth factor D 0.835629
ERBB4 erb-b2 receptor tyrosine kinase 4 0.831584
RELN reelin 0.830304
RDH16 retinol dehydrogenase 16 (all-trans) 0.82192
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 0.815684
TTC1 tetratricopeptide repeat domain 1 0.815307
EGLN2 egl-9 family hypoxia-inducible factor 2 0.811614
MYRIP myosin VIIA and Rab interacting protein 0.808055
CADM1 cell adhesion molecule 1 0.805298
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.798096
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 0.794247
HEG1 heart development protein with EGF-like domains 1 0.793562
DLK1 delta-like 1 homolog (Drosophila) 0.790866
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.790866
LOC100507291 uncharacterized LOC100507291 0.786312
CSMD1 CUB and Sushi multiple domains 1 0.780738
ARPP21 cAMP-regulated phosphoprotein, 21kDa 0.775452
ERAP1 endoplasmic reticulum aminopeptidase 1 0.775167
FLT1 fms-related tyrosine kinase 1 0.766993
HCG23 HLA complex group 23 (non-protein coding) 0.764084
BMPER BMP binding endothelial regulator 0.761811
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 0.756598
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.756598
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.752142
PARK2 parkin RBR E3 ubiquitin protein ligase 0.751629
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 0.743283
HEATR5B HEAT repeat containing 5B 0.738443
PRICKLE1 prickle homolog 1 (Drosophila) 0.730518
LOC100287225 uncharacterized LOC100287225 0.720109
SCGN secretagogin, EF-hand calcium binding protein 0.711585
MTCH2 mitochondrial carrier 2 0.70946
ZFPM2 zinc finger protein, FOG family member 2 0.695042
FAM184A family with sequence similarity 184, member A 0.692747
CLEC4A C-type lectin domain family 4, member A 0.678823
NCOA5 nuclear receptor coactivator 5 0.677979
KLC1 kinesin light chain 1 0.676173
LRRC16A leucine rich repeat containing 16A 0.669341
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.66924
CCDC186 coiled-coil domain containing 186 0.62609
HRH2 histamine receptor H2 0.527413
TDRD1 tudor domain containing 1 0.522865
FAM167A family with sequence similarity 167, member A 0.506603