low-density lipoprotein particle Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A lipoprotein particle, rich in cholesterol esters and low in triglycerides that is typically composed of APOB100 and APOE and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. LDL particles are formed from VLDL particles (via IDL) by the loss of triglyceride and gain of cholesterol ester. They transport endogenous cholesterol (and to some extent triglycerides) from peripheral tissues back to the liver. (Gene Ontology, GO_0034362)
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Genes

533 proteins co-occuring with the low-density lipoprotein particle cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
APOB apolipoprotein B 5.29995
APOA1 apolipoprotein A-I 3.6043
APOE apolipoprotein E 3.60285
COG2 component of oligomeric golgi complex 2 3.59706
CRP C-reactive protein, pentraxin-related 3.52465
LPA lipoprotein, Lp(a) 3.5012
INS insulin 3.0948
LDLR low density lipoprotein receptor 3.01363
CETP cholesteryl ester transfer protein, plasma 2.85847
PON1 paraoxonase 1 2.75692
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 2.648
LPL lipoprotein lipase 2.61375
SCARB1 scavenger receptor class B, member 1 2.59354
LCAT lecithin-cholesterol acyltransferase 2.50556
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 2.48466
ALB albumin 2.40339
PCSK9 proprotein convertase subtilisin/kexin type 9 2.34402
APOA2 apolipoprotein A-II 2.32721
SCARB2 scavenger receptor class B, member 2 2.32562
CD36 CD36 molecule (thrombospondin receptor) 2.30815
APOC3 apolipoprotein C-III 2.28533
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 2.1355
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 2.02204
LEP leptin 2.01556
ACE angiotensin I converting enzyme 1.95583
VCAM1 vascular cell adhesion molecule 1 1.84224
SOD2 superoxide dismutase 2, mitochondrial 1.80707
SHBG sex hormone-binding globulin 1.79442
LIPC lipase, hepatic 1.77405
CCL2 chemokine (C-C motif) ligand 2 1.74067
ICAM1 intercellular adhesion molecule 1 1.74003
IL6 interleukin 6 1.69645
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.68299
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.67933
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.65753
VWF von Willebrand factor 1.64912
SELE selectin E 1.64733
NOS3 nitric oxide synthase 3 (endothelial cell) 1.63956
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.63479
CHD1L chromodomain helicase DNA binding protein 1-like 1.62708
PLG plasminogen 1.60768
GPX1 glutathione peroxidase 1 1.59778
GPX5 glutathione peroxidase 5 1.59372
GPX4 glutathione peroxidase 4 1.59141
PPARG peroxisome proliferator-activated receptor gamma 1.56275
TNF tumor necrosis factor 1.52936
PLA2G1B phospholipase A2, group IB (pancreas) 1.52597
APOH apolipoprotein H (beta-2-glycoprotein I) 1.52371
MTTP microsomal triglyceride transfer protein 1.51299
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 1.51186
TGM4 transglutaminase 4 1.50735
PLTP phospholipid transfer protein 1.50566
PON2 paraoxonase 2 1.49775
MPO myeloperoxidase 1.46382
RETN resistin 1.45703
MYDGF myeloid-derived growth factor 1.44968
SCARF1 scavenger receptor class F, member 1 1.44121
SREBF2 sterol regulatory element binding transcription factor 2 1.43049
CAT catalase 1.41362
GGT1 gamma-glutamyltransferase 1 1.41194
HBA2 hemoglobin, alpha 2 1.39183
HBA1 hemoglobin, alpha 1 1.37741
APOA5 apolipoprotein A-V 1.37299
USF1 upstream transcription factor 1 1.37133
PLAT plasminogen activator, tissue 1.35539
IGF1 insulin-like growth factor 1 (somatomedin C) 1.3125
PON3 paraoxonase 3 1.30766
F7 coagulation factor VII (serum prothrombin conversion accelerator) 1.29906
COG1 component of oligomeric golgi complex 1 1.29746
TF transferrin 1.28196
LIPG lipase, endothelial 1.26392
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.26181
ALPL alkaline phosphatase, liver/bone/kidney 1.22932
ALPPL2 alkaline phosphatase, placental-like 2 1.22828
PPARA peroxisome proliferator-activated receptor alpha 1.22672
ALPP alkaline phosphatase, placental 1.22672
F3 coagulation factor III (thromboplastin, tissue factor) 1.22412
VLDLR very low density lipoprotein receptor 1.20653
CEL carboxyl ester lipase 1.2055
APOF apolipoprotein F 1.20447
PLGLB1 plasminogen-like B1 1.19983
APOC2 apolipoprotein C-II 1.19263
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.15416
SOAT1 sterol O-acyltransferase 1 1.15057
NPC1 Niemann-Pick disease, type C1 1.14648
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.14546
NAMPT nicotinamide phosphoribosyltransferase 1.12858
CSN1S1 casein alpha s1 1.12756
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 1.12347
KDR kinase insert domain receptor 1.1199
MMP9 matrix metallopeptidase 9 1.11174
CXCL16 chemokine (C-X-C motif) ligand 16 1.10562
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 1.10103
IL1B interleukin 1, beta 1.09951
SREBF1 sterol regulatory element binding transcription factor 1 1.099
RBP4 retinol binding protein 4, plasma 1.09442
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 1.04733
DLL1 delta-like 1 (Drosophila) 1.0418
APOM apolipoprotein M 1.03078
FTH1 ferritin, heavy polypeptide 1 1.02979
PCDH8 protocadherin 8 1.02879
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.02829
F8 coagulation factor VIII, procoagulant component 1.01734
CDH5 cadherin 5, type 2 (vascular endothelium) 1.00942
FTL ferritin, light polypeptide 1.00843
ETV3 ets variant 3 1.00054
ELANE elastase, neutrophil expressed 1.00054
F2 coagulation factor II (thrombin) 0.997595
CP ceruloplasmin (ferroxidase) 0.995142
APOA4 apolipoprotein A-IV 0.989759
PTH parathyroid hormone 0.985367
PSRC1 proline/serine-rich coiled-coil 1 0.984393
PROM1 prominin 1 0.982932
CD40LG CD40 ligand 0.982446
EDN1 endothelin 1 0.981959
CD4 CD4 molecule 0.96792
NPC1L1 NPC1-like 1 0.965512
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.964549
APOC1 apolipoprotein C-I 0.956395
MYLIP myosin regulatory light chain interacting protein 0.955917
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.952573
POMC proopiomelanocortin 0.950189
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.950189
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.940689
HP haptoglobin 0.924197
APOD apolipoprotein D 0.922322
KNG1 kininogen 1 0.921854
HCAR2 hydroxycarboxylic acid receptor 2 0.919046
HMGA2 high mobility group AT-hook 2 0.918579
ANGPTL3 angiopoietin-like 3 0.915776
GHRL ghrelin/obestatin prepropeptide 0.915776
CST3 cystatin C 0.914842
PLA2G10 phospholipase A2, group X 0.910647
HPR haptoglobin-related protein 0.903673
FN1 fibronectin 1 0.897646
CD34 CD34 molecule 0.895331
TLR4 toll-like receptor 4 0.894868
CXCL8 chemokine (C-X-C motif) ligand 8 0.890245
REN renin 0.886551
FBXL20 F-box and leucine-rich repeat protein 20 0.884244
GGT2 gamma-glutamyltransferase 2 0.880555
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.880555
KIAA0101 KIAA0101 0.875028
SAA1 serum amyloid A1 0.869505
SORT1 sortilin 1 0.869046
LRP5 low density lipoprotein receptor-related protein 5 0.868126
GSR glutathione reductase 0.863528
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.863068
THBD thrombomodulin 0.862609
LDLRAP1 low density lipoprotein receptor adaptor protein 1 0.86123
NR1H3 nuclear receptor subfamily 1, group H, member 3 0.85388
CD68 CD68 molecule 0.846073
PNLIP pancreatic lipase 0.840105
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 0.836892
SLCO1B1 solute carrier organic anion transporter family, member 1B1 0.830466
FASN fatty acid synthase 0.821746
FADS1 fatty acid desaturase 1 0.811652
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.809817
MSR1 macrophage scavenger receptor 1 0.80523
LRP2 low density lipoprotein receptor-related protein 2 0.802021
TGFB1 transforming growth factor, beta 1 0.787817
FABP2 fatty acid binding protein 2, intestinal 0.785986
VEGFA vascular endothelial growth factor A 0.785529
ESR1 estrogen receptor 1 0.778212
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 0.776841
MMP2 matrix metallopeptidase 2 0.775471
FLT1 fms-related tyrosine kinase 1 0.757253
SDC2 syndecan 2 0.755891
AHSG alpha-2-HS-glycoprotein 0.750452
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.749094
BGN biglycan 0.748189
HMOX1 heme oxygenase 1 0.748189
CD79A CD79a molecule, immunoglobulin-associated alpha 0.740515
PTAFR platelet-activating factor receptor 0.737363
LRP6 low density lipoprotein receptor-related protein 6 0.736014
LEPR leptin receptor 0.736014
IL10 interleukin 10 0.71946
PGF placental growth factor 0.710136
KIF6 kinesin family member 6 0.706156
BGLAP bone gamma-carboxyglutamate (gla) protein 0.706156
LOX lysyl oxidase 0.702626
JUN jun proto-oncogene 0.702626
IFNL3 interferon, lambda 3 0.701304
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.701304
TXNL4B thioredoxin-like 4B 0.699543
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 0.698663
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.689013
FABP4 fatty acid binding protein 4, adipocyte 0.683771
LRP1B low density lipoprotein receptor-related protein 1B 0.681591
ESAM endothelial cell adhesion molecule 0.680284
TTR transthyretin 0.677673
CXCR6 chemokine (C-X-C motif) receptor 6 0.673328
CYBA cytochrome b-245, alpha polypeptide 0.672894
SPINK5 serine peptidase inhibitor, Kazal type 5 0.670725
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.6638
PROS1 protein S (alpha) 0.661208
PCSK7 proprotein convertase subtilisin/kexin type 7 0.659913
SOD3 superoxide dismutase 3, extracellular 0.652159
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.648721
SOAT2 sterol O-acyltransferase 2 0.644429
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.644001
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.642286
CADM1 cell adhesion molecule 1 0.642286
CCR2 chemokine (C-C motif) receptor 2 0.641858
IL18 interleukin 18 0.631598
FADS2 fatty acid desaturase 2 0.622229
FGF2 fibroblast growth factor 2 (basic) 0.617557
GCG glucagon 0.617557
UBAP1 ubiquitin associated protein 1 0.606973
PF4 platelet factor 4 0.60655
ADIPOQ adiponectin, C1Q and collagen domain containing 0.602752
PPP1R3B protein phosphatase 1, regulatory subunit 3B 0.600644
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.599802
SAA2 serum amyloid A2 0.598538
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.597276
FTO fat mass and obesity associated 0.594332
CAV1 caveolin 1, caveolae protein, 22kDa 0.593072
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.588875
CILP2 cartilage intermediate layer protein 2 0.588875
ADRB3 adrenoceptor beta 3 0.583431
TRIB1 tribbles pseudokinase 1 0.582176
HMGA1 high mobility group AT-hook 1 0.574662
PER2 period circadian clock 2 0.568001
BCHE butyrylcholinesterase 0.566754
ANXA5 annexin A5 0.565092
AGER advanced glycosylation end product-specific receptor 0.565092
CBY3 chibby homolog 3 (Drosophila) 0.562187
ACAT1 acetyl-CoA acetyltransferase 1 0.560943
UTS2 urotensin 2 0.557629
CD40 CD40 molecule, TNF receptor superfamily member 5 0.557214
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 0.555145
TTPA tocopherol (alpha) transfer protein 0.553905
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.550186
LIPE lipase, hormone-sensitive 0.549773
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.54194
FGF21 fibroblast growth factor 21 0.539883
TSPO translocator protein (18kDa) 0.537827
PER1 period circadian clock 1 0.535772
PRL prolactin 0.535361
IRF6 interferon regulatory factor 6 0.53413
TLR2 toll-like receptor 2 0.531258
FBL fibrillarin 0.523067
COASY CoA synthase 0.519389
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.51694
FADS3 fatty acid desaturase 3 0.515716
APOC4 apolipoprotein C-IV 0.51327
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.510418
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.508383
STAB1 stabilin 1 0.50757
RXFP1 relaxin/insulin-like family peptide receptor 1 0.506757
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.505944
SCAP SREBF chaperone 0.504724
DGAT2 diacylglycerol O-acyltransferase 2 0.504318
MGAM maltase-glucoamylase 0.503506
IGFBP3 insulin-like growth factor binding protein 3 0.502693
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.499853
NOX4 NADPH oxidase 4 0.499853
DUOX2 dual oxidase 2 0.49742
MMP1 matrix metallopeptidase 1 0.49499
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.492157
LTF lactotransferrin 0.491752
MCAM melanoma cell adhesion molecule 0.490539
NAT10 N-acetyltransferase 10 (GCN5-related) 0.489731
INSR insulin receptor 0.489327
GSTA1 glutathione S-transferase alpha 1 0.488923
GSTA3 glutathione S-transferase alpha 3 0.484483
PBX4 pre-B-cell leukemia homeobox 4 0.484483
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.483273
GSTA2 glutathione S-transferase alpha 2 0.482467
GSTA4 glutathione S-transferase alpha 4 0.482467
DUOX1 dual oxidase 1 0.480855
FGF1 fibroblast growth factor 1 (acidic) 0.479245
VAT1 vesicle amine transport 1 0.477233
IL1A interleukin 1, alpha 0.475625
LIPA lipase A, lysosomal acid, cholesterol esterase 0.473617
PCYOX1 prenylcysteine oxidase 1 0.473215
PLA2G2D phospholipase A2, group IID 0.468802
IGLV3-10 immunoglobulin lambda variable 3-10 0.465198
PLAU plasminogen activator, urokinase 0.465198
IGLV3-9 immunoglobulin lambda variable 3-9 (gene/pseudogene) 0.463997
CD44 CD44 molecule (Indian blood group) 0.463198
STARD8 StAR-related lipid transfer (START) domain containing 8 0.461998
PLIN2 perilipin 2 0.4608
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 0.4608
NPC2 Niemann-Pick disease, type C2 0.460401
CABIN1 calcineurin binding protein 1 0.460401
MAPK3 mitogen-activated protein kinase 3 0.457208
LBP lipopolysaccharide binding protein 0.454418
THADA thyroid adenoma associated 0.454418
TIMP1 TIMP metallopeptidase inhibitor 1 0.452825
TTC39B tetratricopeptide repeat domain 39B 0.452427
VCAN versican 0.451233
FLAD1 flavin adenine dinucleotide synthetase 1 0.446862
MLXIPL MLX interacting protein-like 0.446465
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.443292
SQLE squalene epoxidase 0.4425
CDH13 cadherin 13 0.440916
KLK3 kallikrein-related peptidase 3 0.438146
RXFP2 relaxin/insulin-like family peptide receptor 2 0.43617
MGP matrix Gla protein 0.43617
PDGFB platelet-derived growth factor beta polypeptide 0.432618
CXCL12 chemokine (C-X-C motif) ligand 12 0.429859
IGLV1-47 immunoglobulin lambda variable 1-47 0.41886
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.41612
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.414946
DCN decorin 0.413382
GIP gastric inhibitory polypeptide 0.412992
G6PD glucose-6-phosphate dehydrogenase 0.411039
TFRC transferrin receptor 0.408309
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.40675
DGAT1 diacylglycerol O-acyltransferase 1 0.406361
TTC34 tetratricopeptide repeat domain 34 0.406361
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.40247
CXCL14 chemokine (C-X-C motif) ligand 14 0.401693
ELOVL2 ELOVL fatty acid elongase 2 0.399363
ZPR1 ZPR1 zinc finger 0.398587
ALOX15 arachidonate 15-lipoxygenase 0.389682
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.387751
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.385436
CYGB cytoglobin 0.381584
MVK mevalonate kinase 0.381199
ANGPTL4 angiopoietin-like 4 0.377354
SRY sex determining region Y 0.372366
PNPLA3 patatin-like phospholipase domain containing 3 0.372366
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.369684
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.369301
SIRT1 sirtuin 1 0.368919
MLX MLX, MAX dimerization protein 0.365859
LCA10 lung carcinoma-associated 10 0.365095
NUTM1 NUT midline carcinoma, family member 1 0.364713
PLA2G2E phospholipase A2, group IIE 0.362422
SOST sclerostin 0.360515
FGD1 FYVE, RhoGEF and PH domain containing 1 0.35899
GPR135 G protein-coupled receptor 135 0.355563
GPR85 G protein-coupled receptor 85 0.355183
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 0.352522
MAPK8 mitogen-activated protein kinase 8 0.348346
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.347967
CTSC cathepsin C 0.347208
STAR steroidogenic acute regulatory protein 0.345314
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino 0.343799
CTSD cathepsin D 0.343421
F12 coagulation factor XII (Hageman factor) 0.343421
ADRB2 adrenoceptor beta 2, surface 0.340773
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 0.335487
TNNT2 troponin T type 2 (cardiac) 0.33511
TGM5 transglutaminase 5 0.334733
C6ORF25 chromosome 6 open reading frame 25 0.333979
STAB2 stabilin 2 0.331342
PRODH proline dehydrogenase (oxidase) 1 0.328332
ITLN1 intelectin 1 (galactofuranose binding) 0.327205
ACPP acid phosphatase, prostate 0.325702
SUGP1 SURP and G patch domain containing 1 0.323825
BAX BCL2-associated X protein 0.320077
GLP1R glucagon-like peptide 1 receptor 0.316708
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 0.31596
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 0.315586
ALLC allantoicase 0.315212
ICAM2 intercellular adhesion molecule 2 0.312971
ALOX5 arachidonate 5-lipoxygenase 0.312224
INSL3 insulin-like 3 (Leydig cell) 0.312224
CD86 CD86 molecule 0.308867
CD163 CD163 molecule 0.308494
APOBR apolipoprotein B receptor 0.305515
TPO thyroid peroxidase 0.304399
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.304399
HBEGF heparin-binding EGF-like growth factor 0.304027
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.303283
CBY1 chibby homolog 1 (Drosophila) 0.302168
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.29994
HSPA4 heat shock 70kDa protein 4 0.299569
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 0.299197
IL2 interleukin 2 0.298826
FOXP3 forkhead box P3 0.297713
DPP4 dipeptidyl-peptidase 4 0.297713
FBLL1 fibrillarin-like 1 0.297713
F5 coagulation factor V (proaccelerin, labile factor) 0.296601
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.294748
TIMP2 TIMP metallopeptidase inhibitor 2 0.294748
CPB2 carboxypeptidase B2 (plasma) 0.294378
PPARD peroxisome proliferator-activated receptor delta 0.28846
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.286245
ESR2 estrogen receptor 2 (ER beta) 0.284401
THBS1 thrombospondin 1 0.284032
NOVA2 neuro-oncological ventral antigen 2 0.283295
BTN2A1 butyrophilin, subfamily 2, member A1 0.283295
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.280716
GLB1 galactosidase, beta 1 0.27998
IRS1 insulin receptor substrate 1 0.278877
HPX hemopexin 0.277038
CNR1 cannabinoid receptor 1 (brain) 0.275569
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 0.275202
IGLV9-49 immunoglobulin lambda variable 9-49 0.274835
INSIG2 insulin induced gene 2 0.274101
ACLY ATP citrate lyase 0.2708
IL4 interleukin 4 0.270434
FBLIM1 filamin binding LIM protein 1 0.266042
SRFBP1 serum response factor binding protein 1 0.266042
FGF19 fibroblast growth factor 19 0.265677
EDNRA endothelin receptor type A 0.26239
CMA1 chymase 1, mast cell 0.26239
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.262025
GPANK1 G patch domain and ankyrin repeats 1 0.258745
PRELID2 PRELI domain containing 2 0.258016
ZNF343 zinc finger protein 343 0.258016
SPTY2D1 SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) 0.258016
TAS2R50 taste receptor, type 2, member 50 0.258016
ACSS2 acyl-CoA synthetase short-chain family member 2 0.257652
TBL2 transducin (beta)-like 2 0.257289
PPAN peter pan homolog (Drosophila) 0.254743
S100A8 S100 calcium binding protein A8 0.254743
MMP3 matrix metallopeptidase 3 0.253291
MTNR1B melatonin receptor 1B 0.252564
KLF2 Kruppel-like factor 2 0.252202
DYNLL1 dynein, light chain, LC8-type 1 0.251839
AAAS achalasia, adrenocortical insufficiency, alacrimia 0.251839
CXCR2 chemokine (C-X-C motif) receptor 2 0.250389
GPX3 glutathione peroxidase 3 0.247854
SLC22A18 solute carrier family 22, member 18 0.247854
MAPK14 mitogen-activated protein kinase 14 0.247492
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.246046
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.242797
IGLV5-48 immunoglobulin lambda variable 5-48 (non-functional) 0.241716
FAM174A family with sequence similarity 174, member A 0.240996
GPR25 G protein-coupled receptor 25 0.240996
MYBPHL myosin binding protein H-like 0.240996
CFAP44 cilia and flagella associated protein 44 0.240996
MAMSTR MEF2 activating motif and SAP domain containing transcriptional regulator 0.240996
PLIN1 perilipin 1 0.238119
C5AR1 complement component 5a receptor 1 0.237401
EGR1 early growth response 1 0.237042
CTSS cathepsin S 0.234533
DHCR7 7-dehydrocholesterol reductase 0.233459
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.233459
NOS2 nitric oxide synthase 2, inducible 0.233101
PEMT phosphatidylethanolamine N-methyltransferase 0.231672
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.231315
HDLBP high density lipoprotein binding protein 0.231315
ATR ATR serine/threonine kinase 0.230601
SCP2 sterol carrier protein 2 0.227041
ARHGAP4 Rho GTPase activating protein 4 0.226331
SELL selectin L 0.225267
MB myoglobin 0.224204
AFP alpha-fetoprotein 0.224204
CLU clusterin 0.223497
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.222436
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.220673
BPI bactericidal/permeability-increasing protein 0.220321
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 0.220321
SPP1 secreted phosphoprotein 1 0.220321
CSF1R colony stimulating factor 1 receptor 0.218914
PYY peptide YY 0.21681
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.212627
F9 coagulation factor IX 0.211933
C3 complement component 3 0.209513
STX8 syntaxin 8 0.209169
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.207794
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.207794
CUTA cutA divalent cation tolerance homolog (E. coli) 0.207451
ADIPOR1 adiponectin receptor 1 0.207451
MAPK9 mitogen-activated protein kinase 9 0.206766
TP53 tumor protein p53 0.204718
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1 0.203022
CXCL10 chemokine (C-X-C motif) ligand 10 0.202684
APCS amyloid P component, serum 0.201672
GPR171 G protein-coupled receptor 171 0.200999
MMP12 matrix metallopeptidase 12 0.199993
IGFBP1 insulin-like growth factor binding protein 1 0.198325
C5AR2 complement component 5a receptor 2 0.196999
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 0.19601
ZCCHC16 zinc finger, CCHC domain containing 16 0.195681
INSIG1 insulin induced gene 1 0.193394
FOS FBJ murine osteosarcoma viral oncogene homolog 0.191135
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 0.190495
LST1 leukocyte specific transcript 1 0.189539
OSBP oxysterol binding protein 0.188905
CCDC92 coiled-coil domain containing 92 0.18796
SEBOX SEBOX homeobox 0.187646
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.185777
GPR83 G protein-coupled receptor 83 0.184853
OSBPL11 oxysterol binding protein-like 11 0.184241
PDGFC platelet derived growth factor C 0.183935
MAP9 microtubule-associated protein 9 0.182122
PRRC2A proline-rich coiled-coil 2A 0.181227
ADIPOR2 adiponectin receptor 2 0.181227
MANF mesencephalic astrocyte-derived neurotrophic factor 0.180634
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.179459
NAAA N-acylethanolamine acid amidase 0.178877
PER3 period circadian clock 3 0.178877
TMEM57 transmembrane protein 57 0.178588
LDHD lactate dehydrogenase D 0.178299
ACAT2 acetyl-CoA acetyltransferase 2 0.177724
CD81 CD81 molecule 0.175745
MIR146A microRNA 146a 0.174361
CFD complement factor D (adipsin) 0.173003
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.172201
PAPPA pregnancy-associated plasma protein A, pappalysin 1 0.172201
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 0.171673
STAP1 signal transducing adaptor family member 1 0.17141
SP6 Sp6 transcription factor 0.17141
NPPA natriuretic peptide A 0.171149
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.170888
APOL1 apolipoprotein L, 1 0.170114
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.16935
GHSR growth hormone secretagogue receptor 0.168847
SLC35E2B solute carrier family 35, member E2B 0.168101
PLA2G2F phospholipase A2, group IIF 0.168101
AMY2A amylase, alpha 2A (pancreatic) 0.167856
MLN motilin 0.167366
LY6D lymphocyte antigen 6 complex, locus D 0.167125
ANOS1 anosmin 1 0.166884
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.166167
HAMP hepcidin antimicrobial peptide 0.165932
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 0.165463
TG thyroglobulin 0.165231
NDP Norrie disease (pseudoglioma) 0.164315
MMP28 matrix metallopeptidase 28 0.164089
SAR1B secretion associated, Ras related GTPase 1B 0.163641
MIB2 mindbomb E3 ubiquitin protein ligase 2 0.16342
PLA2G5 phospholipase A2, group V 0.161905
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.160863
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.160658
C1QTNF9 C1q and tumor necrosis factor related protein 9 0.160658
IGLV1-50 immunoglobulin lambda variable 1-50 (non-functional) 0.160456
ACTG1 actin gamma 1 0.160254
CCL13 chemokine (C-C motif) ligand 13 0.158502
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 0.158129
CMC2 C-x(9)-C motif containing 2 0.157578
GC group-specific component (vitamin D binding protein) 0.157397
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 0.157218
DDIT4L DNA-damage-inducible transcript 4-like 0.157218
M6PR mannose-6-phosphate receptor (cation dependent) 0.156513
CARTPT CART prepropeptide 0.156513