low-density lipoprotein particle Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A lipoprotein particle, rich in cholesterol esters and low in triglycerides that is typically composed of APOB100 and APOE and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. LDL particles are formed from VLDL particles (via IDL) by the loss of triglyceride and gain of cholesterol ester. They transport endogenous cholesterol (and to some extent triglycerides) from peripheral tissues back to the liver. (Gene Ontology, GO_0034362)
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13 proteins localized to the low-density lipoprotein particle cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.237908
VIMP VCP-interacting membrane selenoprotein 0.237908
APOM apolipoprotein M 0.237908
APOB apolipoprotein B 0.237908
APOE apolipoprotein E 0.237908
APOC2 apolipoprotein C-II 0.237908
APOF apolipoprotein F 0.098109
LDLR low density lipoprotein receptor 0.098109
APOO apolipoprotein O 0.098109
LSR lipolysis stimulated lipoprotein receptor 0.098109
APOBR apolipoprotein B receptor 0.098109
MSR1 macrophage scavenger receptor 1 0.098109
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.098109