loracarbef-3532 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the loracarbef-3532 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
AHCYL1 adenosylhomocysteinase-like 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ANKH ANKH inorganic pyrophosphate transport regulator
AOX1 aldehyde oxidase 1
APOE apolipoprotein E
AQP1 aquaporin 1 (Colton blood group)
AR androgen receptor
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARMC4 armadillo repeat containing 4
ATF6B activating transcription factor 6 beta
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
BCL6 B-cell CLL/lymphoma 6
BHMT2 betaine--homocysteine S-methyltransferase 2
BTF3P11 basic transcription factor 3 pseudogene 11
BTNL2 butyrophilin-like 2
CARTPT CART prepropeptide
CCR9 chemokine (C-C motif) receptor 9
CD83 CD83 molecule
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLIC2 chloride intracellular channel 2
CRMP1 collapsin response mediator protein 1
CRYGC crystallin, gamma C
CSF1R colony stimulating factor 1 receptor
DMPK dystrophia myotonica-protein kinase
DOCK9 dedicator of cytokinesis 9
DOK4 docking protein 4
DYM dymeclin
EDA ectodysplasin A
ELOVL5 ELOVL fatty acid elongase 5
EPHB2 EPH receptor B2
FAM120C family with sequence similarity 120C
FGF21 fibroblast growth factor 21
FOXH1 forkhead box H1
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GLDC glycine dehydrogenase (decarboxylating)
GPR22 G protein-coupled receptor 22
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HIST1H4E histone cluster 1, H4e
HMOX1 heme oxygenase 1
HNRNPM heterogeneous nuclear ribonucleoprotein M
ICOSLG inducible T-cell co-stimulator ligand
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IGL immunoglobulin lambda locus
ITGB7 integrin, beta 7
JADE2 jade family PHD finger 2
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KLF12 Kruppel-like factor 12
KRT6B keratin 6B, type II
LINC01587 long intergenic non-protein coding RNA 1587
LY6G6C lymphocyte antigen 6 complex, locus G6C
MIP major intrinsic protein of lens fiber
MPZ myelin protein zero
MYBPC3 myosin binding protein C, cardiac
NIPAL2 NIPA-like domain containing 2
NPAS2 neuronal PAS domain protein 2
NPY4R neuropeptide Y receptor Y4
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR7A10 olfactory receptor, family 7, subfamily A, member 10
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH11Y protocadherin 11 Y-linked
PDE4D phosphodiesterase 4D, cAMP-specific
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
POU4F2 POU class 4 homeobox 2
PPARD peroxisome proliferator-activated receptor delta
PRDX2 peroxiredoxin 2
PSG1 pregnancy specific beta-1-glycoprotein 1
PTAFR platelet-activating factor receptor
PTCRA pre T-cell antigen receptor alpha
PTHLH parathyroid hormone-like hormone
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RBM5 RNA binding motif protein 5
REPS1 RALBP1 associated Eps domain containing 1
RGS12 regulator of G-protein signaling 12
RND1 Rho family GTPase 1
RPS3A ribosomal protein S3A
SAFB2 scaffold attachment factor B2
SDC3 syndecan 3
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SLN sarcolipin
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SYNE1 spectrin repeat containing, nuclear envelope 1
TBX5 T-box 5
TLR2 toll-like receptor 2
TRAF3IP3 TRAF3 interacting protein 3
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TROVE2 TROVE domain family, member 2
UBA7 ubiquitin-like modifier activating enzyme 7
UNC93B1 unc-93 homolog B1 (C. elegans)
YOD1 YOD1 deubiquitinase
ZG16 zymogen granule protein 16
ZNF419 zinc finger protein 419
ZNF493 zinc finger protein 493
ZSCAN31 zinc finger and SCAN domain containing 31

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACAD10 acyl-CoA dehydrogenase family, member 10
ADAP2 ArfGAP with dual PH domains 2
ADCY6 adenylate cyclase 6
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA2P3 annexin A2 pseudogene 3
APOLD1 apolipoprotein L domain containing 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C10ORF95 chromosome 10 open reading frame 95
C14ORF79 chromosome 14 open reading frame 79
C19ORF40 chromosome 19 open reading frame 40
C5AR2 complement component 5a receptor 2
C5ORF45 chromosome 5 open reading frame 45
C6ORF47 chromosome 6 open reading frame 47
CBX8 chromobox homolog 8
CCDC121 coiled-coil domain containing 121
CXCR2 chemokine (C-X-C motif) receptor 2
DGKE diacylglycerol kinase, epsilon 64kDa
DPY19L1P1 DPY19L1 pseudogene 1
DUSP5 dual specificity phosphatase 5
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFHD2 EF-hand domain family, member D2
ERO1L ERO1-like (S. cerevisiae)
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM46C family with sequence similarity 46, member C
FBXL6 F-box and leucine-rich repeat protein 6
FLNC filamin C, gamma
FSTL3 follistatin-like 3 (secreted glycoprotein)
FUZ fuzzy planar cell polarity protein
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPS1 G protein pathway suppressor 1
GRTP1 growth hormone regulated TBC protein 1
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2BC histone cluster 1, H2bc
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC10 homeobox C10
IL4R interleukin 4 receptor
INPP1 inositol polyphosphate-1-phosphatase
JMJD4 jumonji domain containing 4
KIF13A kinesin family member 13A
KLK5 kallikrein-related peptidase 5
LAMB3 laminin, beta 3
LARP6 La ribonucleoprotein domain family, member 6
LIME1 Lck interacting transmembrane adaptor 1
LRRC16A leucine rich repeat containing 16A
LRRC61 leucine rich repeat containing 61
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGEA6 melanoma antigen family A6
MANBA mannosidase, beta A, lysosomal
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MED9 mediator complex subunit 9
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MXD3 MAX dimerization protein 3
MYL5 myosin, light chain 5, regulatory
NNAT neuronatin
NPFFR1 neuropeptide FF receptor 1
PACS1 phosphofurin acidic cluster sorting protein 1
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDLIM2 PDZ and LIM domain 2 (mystique)
PGP phosphoglycolate phosphatase
PIBF1 progesterone immunomodulatory binding factor 1
PLD2 phospholipase D2
POM121 POM121 transmembrane nucleoporin
PROS1 protein S (alpha)
PTCD2 pentatricopeptide repeat domain 2
RANBP17 RAN binding protein 17
RANGRF RAN guanine nucleotide release factor
RASL11B RAS-like, family 11, member B
RIBC2 RIB43A domain with coiled-coils 2
RPAP1 RNA polymerase II associated protein 1
RPAP2 RNA polymerase II associated protein 2
SCRN3 secernin 3
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SH2D4A SH2 domain containing 4A
SKI SKI proto-oncogene
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC12A9 solute carrier family 12, member 9
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
STAG3 stromal antigen 3
STXBP2 syntaxin binding protein 2
SUN2 Sad1 and UNC84 domain containing 2
SYNGR3 synaptogyrin 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TRABD TraB domain containing
TRPM4 transient receptor potential cation channel, subfamily M, member 4
VEGFB vascular endothelial growth factor B
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
WDR18 WD repeat domain 18
YEATS2 YEATS domain containing 2
ZNF282 zinc finger protein 282
ZNF329 zinc finger protein 329
ZNF350 zinc finger protein 350
ZNF623 zinc finger protein 623