locus ceruleus Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
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Genes

217 proteins co-occuring with the tissue locus ceruleus in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
TH tyrosine hydroxylase 3.15334
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 2.68299
FOS FBJ murine osteosarcoma viral oncogene homolog 2.53898
CRH corticotropin releasing hormone 2.35865
HCRT hypocretin (orexin) neuropeptide precursor 2.11126
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 2.0514
GAL galanin/GMAP prepropeptide 2.03589
PNMT phenylethanolamine N-methyltransferase 1.87805
OPRM1 opioid receptor, mu 1 1.69002
CHAT choline O-acetyltransferase 1.62207
NPY neuropeptide Y 1.61061
POMC proopiomelanocortin 1.55795
TAC1 tachykinin, precursor 1 1.52808
NPS neuropeptide S 1.5119
PHOX2A paired-like homeobox 2a 1.48411
MAOA monoamine oxidase A 1.451
ADRA2A adrenoceptor alpha 2A 1.44914
CRHR1 corticotropin releasing hormone receptor 1 1.41169
GALR3 galanin receptor 3 1.35722
TPH1 tryptophan hydroxylase 1 1.35086
MAOB monoamine oxidase B 1.30658
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.27561
HCRTR1 hypocretin (orexin) receptor 1 1.24922
GALR1 galanin receptor 1 1.24208
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 1.21446
ADRA2C adrenoceptor alpha 2C 1.19534
SST somatostatin 1.18601
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 1.18468
TACR1 tachykinin receptor 1 1.17225
ACHE acetylcholinesterase (Yt blood group) 1.0996
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.09916
GALR2 galanin receptor 2 1.08987
BDNF brain-derived neurotrophic factor 1.07265
GCH1 GTP cyclohydrolase 1 1.06074
OPRL1 opiate receptor-like 1 1.05941
PNOC prepronociceptin 1.04445
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.03917
NTS neurotensin 1.03741
PDYN prodynorphin 1.01549
TECTA tectorin alpha 0.991509
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.983688
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.95988
CORT cortistatin 0.929335
NTF3 neurotrophin 3 0.915642
GDNF glial cell derived neurotrophic factor 0.896045
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 0.875284
CARTPT CART prepropeptide 0.847904
UCN urocortin 0.844545
TXNL4B thioredoxin-like 4B 0.816068
NGF nerve growth factor (beta polypeptide) 0.807716
CREB1 cAMP responsive element binding protein 1 0.798958
PORCN porcupine homolog (Drosophila) 0.795624
PENK proenkephalin 0.747927
RGS4 regulator of G-protein signaling 4 0.740915
MAPT microtubule-associated protein tau 0.735559
CCK cholecystokinin 0.735559
MECP2 methyl CpG binding protein 2 0.733912
ASCL1 achaete-scute family bHLH transcription factor 1 0.730208
TRH thyrotropin-releasing hormone 0.729797
OXR1 oxidation resistance 1 0.719113
AVP arginine vasopressin 0.718703
PTH2R parathyroid hormone 2 receptor 0.718703
APP amyloid beta (A4) precursor protein 0.71501
MEA1 male-enhanced antigen 1 0.706402
TPH2 tryptophan hydroxylase 2 0.693311
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.684327
NPSR1 neuropeptide S receptor 1 0.670471
ADCY2 adenylate cyclase 2 (brain) 0.665995
FAT1 FAT atypical cadherin 1 0.661523
ADRBK2 adrenergic, beta, receptor kinase 2 0.656242
GPR151 G protein-coupled receptor 151 0.654212
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.6461
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.641238
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 0.637999
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.637594
CA1 carbonic anhydrase I 0.633549
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.63274
SSTR1 somatostatin receptor 1 0.631527
PTH2 parathyroid hormone 2 0.627081
ATF2 activating transcription factor 2 0.625465
NPB neuropeptide B 0.622235
UCN2 urocortin 2 0.617796
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.614167
HCRTR2 hypocretin (orexin) receptor 2 0.612958
CALCA calcitonin-related polypeptide alpha 0.612958
RNF180 ring finger protein 180 0.606916
NTF4 neurotrophin 4 0.605709
CA4 carbonic anhydrase IV 0.59124
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 0.584022
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 0.579617
DRD2 dopamine receptor D2 0.565631
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 0.562042
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 0.547326
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.545342
PREPL prolyl endopeptidase-like 0.543756
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.540585
NGB neuroglobin 0.537021
TROVE2 TROVE domain family, member 2 0.535438
JAG2 jagged 2 0.522011
CDC37L1 cell division cycle 37-like 1 0.518859
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.515317
LHB luteinizing hormone beta polypeptide 0.514924
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.500007
IL1B interleukin 1, beta 0.49844
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.491791
CGA glycoprotein hormones, alpha polypeptide 0.488667
TAAR1 trace amine associated receptor 1 0.485935
ARRB2 arrestin, beta 2 0.485545
JUN jun proto-oncogene 0.483206
ADRA2B adrenoceptor alpha 2B 0.482817
ESR2 estrogen receptor 2 (ER beta) 0.476589
FOXP2 forkhead box P2 0.473869
OXT oxytocin/neurophysin I prepropeptide 0.467273
UCN3 urocortin 3 0.460692
NR2F6 nuclear receptor subfamily 2, group F, member 6 0.459918
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.446422
GRM5 glutamate receptor, metabotropic 5 0.445653
TACR3 tachykinin receptor 3 0.443731
PPY pancreatic polypeptide 0.443731
HLA-DOB major histocompatibility complex, class II, DO beta 0.442962
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.442194
QPCT glutaminyl-peptide cyclotransferase 0.438739
OR13H1 olfactory receptor, family 13, subfamily H, member 1 0.437205
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1 0.436438
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.435289
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.43414
SYT17 synaptotagmin XVII 0.432991
ARRB1 arrestin, beta 1 0.432225
BCHE butyrylcholinesterase 0.428401
CNR1 cannabinoid receptor 1 (brain) 0.424963
GPHN gephyrin 0.422673
NRTN neurturin 0.41848
RGS7 regulator of G-protein signaling 7 0.418099
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 0.412771
GRM2 glutamate receptor, metabotropic 2 0.410491
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 0.40328
HK1 hexokinase 1 0.391931
NPPA natriuretic peptide A 0.391931
IARS isoleucyl-tRNA synthetase 0.387781
EN2 engrailed homeobox 2 0.387404
STK38 serine/threonine kinase 38 0.384766
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 0.38439
CALB1 calbindin 1, 28kDa 0.384013
GRM7 glutamate receptor, metabotropic 7 0.381755
KCNK10 potassium channel, two pore domain subfamily K, member 10 0.377996
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.374993
PHOX2B paired-like homeobox 2b 0.373493
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.373118
CREB3 cAMP responsive element binding protein 3 0.36825
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.366381
GCHFR GTP cyclohydrolase I feedback regulator 0.365633
PSPN persephin 0.364886
INS insulin 0.362273
PARK2 parkin RBR E3 ubiquitin protein ligase 0.358546
TMEM245 transmembrane protein 245 0.351485
SCG5 secretogranin V 0.351485
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.345928
GLB1 galactosidase, beta 1 0.340757
KCNK1 potassium channel, two pore domain subfamily K, member 1 0.340019
PACRG PARK2 co-regulated 0.340019
GPR88 G protein-coupled receptor 88 0.336704
PSEN1 presenilin 1 0.334498
SSTR2 somatostatin receptor 2 0.332294
SNPH syntaphilin 0.33046
VIP vasoactive intestinal peptide 0.328628
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 0.32753
GRM4 glutamate receptor, metabotropic 4 0.32753
F8A2 coagulation factor VIII-associated 2 0.326067
F8A1 coagulation factor VIII-associated 1 0.326067
PTK7 protein tyrosine kinase 7 (inactive) 0.320956
EDC3 enhancer of mRNA decapping 3 0.318042
TRIM37 tripartite motif containing 37 0.317315
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.315135
SNCB synuclein, beta 0.310783
ADRB2 adrenoceptor beta 2, surface 0.310421
BMP5 bone morphogenetic protein 5 0.306805
C3ORF18 chromosome 3 open reading frame 18 0.303559
ESR1 estrogen receptor 1 0.303198
APEH acylaminoacyl-peptide hydrolase 0.292793
RGS9 regulator of G-protein signaling 9 0.292079
ATXN3 ataxin 3 0.289939
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 0.289939
NUB1 negative regulator of ubiquitin-like proteins 1 0.285671
ADM adrenomedullin 0.280012
PVALB parvalbumin 0.276495
SNED1 sushi, nidogen and EGF-like domains 1 0.273696
ARFRP1 ADP-ribosylation factor related protein 1 0.267791
EGR1 early growth response 1 0.262304
FGF8 fibroblast growth factor 8 (androgen-induced) 0.261964
RNASEH2A ribonuclease H2, subunit A 0.261624
CRHR2 corticotropin releasing hormone receptor 2 0.259591
CNTN2 contactin 2 (axonal) 0.25457
KCNK5 potassium channel, two pore domain subfamily K, member 5 0.254239
NGFR nerve growth factor receptor 0.249653
IGKV1-17 immunoglobulin kappa variable 1-17 0.24676
HSPB8 heat shock 22kDa protein 8 0.244545
SYP synaptophysin 0.243294
SNCG synuclein, gamma (breast cancer-specific protein 1) 0.240826
ENO2 enolase 2 (gamma, neuronal) 0.239307
KCNK9 potassium channel, two pore domain subfamily K, member 9 0.239007
BACE1 beta-site APP-cleaving enzyme 1 0.238108
SCG2 secretogranin II 0.237513
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 0.236627
GPR50 G protein-coupled receptor 50 0.23604
GFAP glial fibrillary acidic protein 0.235748
CCKBR cholecystokinin B receptor 0.235167
CRBN cereblon 0.233731
ARTN artemin 0.233446
TACR2 tachykinin receptor 2 0.225647
GSTM1 glutathione S-transferase mu 1 0.225144
GLP1R glucagon-like peptide 1 receptor 0.223177
LPP LIM domain containing preferred translocation partner in lipoma 0.216933
CREM cAMP responsive element modulator 0.21673
RTN4 reticulon 4 0.215341
NRL neural retina leucine zipper 0.214202
DMBX1 diencephalon/mesencephalon homeobox 1 0.213833
PDE4C phosphodiesterase 4C, cAMP-specific 0.212413