lobelanidine-2897 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the lobelanidine-2897 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADAP2 ArfGAP with dual PH domains 2
AK1 adenylate kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
ARTN artemin
ASPHD1 aspartate beta-hydroxylase domain containing 1
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CD34 CD34 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD82 CD82 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDRT1 CMT1A duplicated region transcript 1
CNTNAP2 contactin associated protein-like 2
COL8A1 collagen, type VIII, alpha 1
CORT cortistatin
CTSF cathepsin F
CTSZ cathepsin Z
DAGLA diacylglycerol lipase, alpha
DNAI2 dynein, axonemal, intermediate chain 2
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DOK4 docking protein 4
EHBP1L1 EH domain binding protein 1-like 1
FOXG1 forkhead box G1
GAS2 growth arrest-specific 2
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GRPR gastrin-releasing peptide receptor
HLA-DRA major histocompatibility complex, class II, DR alpha
HR hair growth associated
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IFI6 interferon, alpha-inducible protein 6
IL1RN interleukin 1 receptor antagonist
INHBA inhibin, beta A
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0319L KIAA0319-like
KIDINS220 kinase D-interacting substrate, 220kDa
KLHL25 kelch-like family member 25
LAMA4 laminin, alpha 4
LARP6 La ribonucleoprotein domain family, member 6
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
MBD3 methyl-CpG binding domain protein 3
MGAM maltase-glucoamylase
MIR622 microRNA 622
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MYOF myoferlin
N4BP3 NEDD4 binding protein 3
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCF4 neutrophil cytosolic factor 4, 40kDa
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NEU3 sialidase 3 (membrane sialidase)
NEURL1 neuralized E3 ubiquitin protein ligase 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRTN neurturin
NUMA1 nuclear mitotic apparatus protein 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PAX5 paired box 5
PC pyruvate carboxylase
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLAUR plasminogen activator, urokinase receptor
PLD1 phospholipase D1, phosphatidylcholine-specific
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRB3 proline-rich protein BstNI subfamily 3
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RAD54L2 RAD54-like 2 (S. cerevisiae)
RPL23AP32 ribosomal protein L23a pseudogene 32
RUNX1 runt-related transcription factor 1
RXRB retinoid X receptor, beta
S100A8 S100 calcium binding protein A8
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIPA1L3 signal-induced proliferation-associated 1 like 3
SIRPA signal-regulatory protein alpha
SMC1A structural maintenance of chromosomes 1A
SRCAP Snf2-related CREBBP activator protein
SSX3 synovial sarcoma, X breakpoint 3
SUGP2 SURP and G patch domain containing 2
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAPBP TAP binding protein (tapasin)
TEF thyrotrophic embryonic factor
TLR8 toll-like receptor 8
TMEM144 transmembrane protein 144
TMEM8B transmembrane protein 8B
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TRIM3 tripartite motif containing 3
TSC22D4 TSC22 domain family, member 4
TXNRD2 thioredoxin reductase 2
UPK3A uroplakin 3A
XYLB xylulokinase homolog (H. influenzae)
YPEL1 yippee-like 1 (Drosophila)
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF205 zinc finger protein 205
ZNF484 zinc finger protein 484
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACTL8 actin-like 8
ANKRD40 ankyrin repeat domain 40
BATF basic leucine zipper transcription factor, ATF-like
BCL9 B-cell CLL/lymphoma 9
BRAF B-Raf proto-oncogene, serine/threonine kinase
C1ORF105 chromosome 1 open reading frame 105
C1QTNF3 C1q and tumor necrosis factor related protein 3
CALCOCO1 calcium binding and coiled-coil domain 1
CAPN5 calpain 5
CARF calcium responsive transcription factor
CCDC9 coiled-coil domain containing 9
CCNO cyclin O
CEP112 centrosomal protein 112kDa
CHKB choline kinase beta
CLCF1 cardiotrophin-like cytokine factor 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CUZD1 CUB and zona pellucida-like domains 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
EDAR ectodysplasin A receptor
ELOVL4 ELOVL fatty acid elongase 4
EML4 echinoderm microtubule associated protein like 4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
F8 coagulation factor VIII, procoagulant component
FAM110B family with sequence similarity 110, member B
FAM76A family with sequence similarity 76, member A
FBXL2 F-box and leucine-rich repeat protein 2
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FKBP1B FK506 binding protein 1B, 12.6 kDa
FRK fyn-related Src family tyrosine kinase
GALT galactose-1-phosphate uridylyltransferase
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR176 G protein-coupled receptor 176
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HDAC11 histone deacetylase 11
HIST1H2AJ histone cluster 1, H2aj
HOXC4 homeobox C4
HSPA1L heat shock 70kDa protein 1-like
IPO8 importin 8
JRKL JRK-like
KIF13A kinesin family member 13A
KLF3 Kruppel-like factor 3 (basic)
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LPPR1 lipid phosphate phosphatase-related protein type 1
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAPK10 mitogen-activated protein kinase 10
MDM4 MDM4, p53 regulator
MED18 mediator complex subunit 18
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MYO1F myosin IF
NIPAL2 NIPA-like domain containing 2
NME5 NME/NM23 family member 5
NR1H3 nuclear receptor subfamily 1, group H, member 3
NRSN2 neurensin 2
NUP62CL nucleoporin 62kDa C-terminal like
OSMR oncostatin M receptor
OTUD3 OTU deubiquitinase 3
PARG poly (ADP-ribose) glycohydrolase
PHC1 polyhomeotic homolog 1 (Drosophila)
PHF14 PHD finger protein 14
PLCD1 phospholipase C, delta 1
PRPH peripherin
PTPRU protein tyrosine phosphatase, receptor type, U
RASL11B RAS-like, family 11, member B
SCHIP1 schwannomin interacting protein 1
SLC22A14 solute carrier family 22, member 14
SLIT2 slit homolog 2 (Drosophila)
SPIDR scaffolding protein involved in DNA repair
STRA6 stimulated by retinoic acid 6
STX1A syntaxin 1A (brain)
TEX14 testis expressed 14
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFF2 trefoil factor 2
TM6SF1 transmembrane 6 superfamily member 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMC5 transmembrane channel-like 5
TMEM110 transmembrane protein 110
TMEM254 transmembrane protein 254
TMEM38B transmembrane protein 38B
TTBK2 tau tubulin kinase 2
TTC33 tetratricopeptide repeat domain 33
TYRP1 tyrosinase-related protein 1
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBQLN4 ubiquilin 4
USP19 ubiquitin specific peptidase 19
ZBTB6 zinc finger and BTB domain containing 6
ZFHX2 zinc finger homeobox 2
ZNF204P zinc finger protein 204, pseudogene
ZNF350 zinc finger protein 350
ZNF41 zinc finger protein 41
ZNF532 zinc finger protein 532
ZNF551 zinc finger protein 551