lipoprotein Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of TRIGLYCERIDES and CHOLESTEROL ESTERS surrounded by a layer of hydrophilic free CHOLESTEROL; PHOSPHOLIPIDS; and APOLIPOPROTEINS. Lipoproteins are classified by their varying buoyant density and sizes. (Experimental Factor Ontology, EFO_0003836)
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Genes

18 genes associated with the disease lipoprotein in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
APOA1 apolipoprotein A-I
APOA4 apolipoprotein A-IV
APOB apolipoprotein B
APOC1 apolipoprotein C-I
APOC3 apolipoprotein C-III
APOE apolipoprotein E
APOH apolipoprotein H (beta-2-glycoprotein I)
CD14 CD14 molecule
CETP cholesteryl ester transfer protein, plasma
CYBA cytochrome b-245, alpha polypeptide
FABP1 fatty acid binding protein 1, liver
IL1RN interleukin 1 receptor antagonist
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
LIPC lipase, hepatic
LPL lipoprotein lipase
PON1 paraoxonase 1