lewy neurite Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Elongated neuronal process, often with side branches and more than one branching point, described in brains of patients with Parkinson's disease. Lewy neurites stain positively for ubiquitin in brainstem and forebrain regions affected in Parkinson's disease. (Gene Ontology, GO_0097462)
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Genes

40 proteins co-occuring with the lewy neurite cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
IGKV1-17 immunoglobulin kappa variable 1-17 2.15079
SNCB synuclein, beta 1.9084
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.67568
SNCAIP synuclein, alpha interacting protein 1.50961
SNCG synuclein, gamma (breast cancer-specific protein 1) 1.48984
LRRK2 leucine-rich repeat kinase 2 1.066
SPG11 spastic paraplegia 11 (autosomal recessive) 0.939269
BAG5 BCL2-associated athanogene 5 0.874567
C19ORF12 chromosome 19 open reading frame 12 0.843778
FBXO7 F-box protein 7 0.725258
PRND prion protein 2 (dublet) 0.68508
TH tyrosine hydroxylase 0.678978
UBC ubiquitin C 0.65388
RPS27A ribosomal protein S27a 0.627761
UBB ubiquitin B 0.611201
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 0.59896
C9ORF72 chromosome 9 open reading frame 72 0.567169
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 0.559285
ITM2B integral membrane protein 2B 0.532488
WDFY2 WD repeat and FYVE domain containing 2 0.514493
PARK7 parkinson protein 7 0.482064
BCHE butyrylcholinesterase 0.480453
SPTBN1 spectrin, beta, non-erythrocytic 1 0.438937
MAPT microtubule-associated protein tau 0.421212
OPTN optineurin 0.420428
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.413382
AXL AXL receptor tyrosine kinase 0.357086
SYP synaptophysin 0.340773
FOXO3 forkhead box O3 0.333979
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 0.304771
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.291417
HDC histidine decarboxylase 0.271167
NPTX2 neuronal pentraxin II 0.239197
HSPA4 heat shock 70kDa protein 4 0.202684
MAP4 microtubule-associated protein 4 0.193719
LATS1 large tumor suppressor kinase 1 0.179459
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.176305
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.163865
PHB prohibitin 0.161484
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.157218