left-sided isomerism Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the asymmetry of the visceral paired organs (e.g. lungs) such that organs on the left and right side have the morphology normally seen on the left side of the body; this may also be associated with the presence of multiple spleens (Mammalian Phenotype Ontology, MP_0000542)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000542
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Genes

26 gene mutations causing the left-sided isomerism phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ATMIN ATM interactor
CCDC39 coiled-coil domain containing 39
CCDC40 coiled-coil domain containing 40
CEP290 centrosomal protein 290kDa
CFC1 cripto, FRL-1, cryptic family 1
DAND5 DAN domain family member 5, BMP antagonist
DAW1 dynein assembly factor with WDR repeat domains 1
DNAAF3 dynein, axonemal, assembly factor 3
DNAH11 dynein, axonemal, heavy chain 11
DNAH5 dynein, axonemal, heavy chain 5
DNAI1 dynein, axonemal, intermediate chain 1
DRC1 dynein regulatory complex subunit 1
HHIP hedgehog interacting protein
HSPB11 heat shock protein family B (small), member 11
IFT140 intraflagellar transport 140
INVS inversin
LEFTY1 left-right determination factor 1
LEFTY2 left-right determination factor 2
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MKS1 Meckel syndrome, type 1
MNS1 meiosis-specific nuclear structural 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PKD2 polycystic kidney disease 2 (autosomal dominant)
RPGRIP1L RPGRIP1-like
TBC1D32 TBC1 domain family, member 32
ZIC3 Zic family member 3