leading edge membrane Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description The portion of the plasma membrane surrounding the leading edge of a motile cell. (Gene Ontology, GO_0031256)
External Link http://amigo.geneontology.org/amigo/term/GO:0031256
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Genes

123 proteins localized to the leading edge membrane cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADAM17 ADAM metallopeptidase domain 17
ADGRE2 adhesion G protein-coupled receptor E2
ADORA1 adenosine A1 receptor
AIF1 allograft inflammatory factor 1
AIF1L allograft inflammatory factor 1-like
AKT2 v-akt murine thymoma viral oncogene homolog 2
AMPH amphiphysin
ANK1 ankyrin 1, erythrocytic
ANTXR1 anthrax toxin receptor 1
APC adenomatous polyposis coli
APC2 adenomatosis polyposis coli 2
ARF4 ADP-ribosylation factor 4
ARHGAP44 Rho GTPase activating protein 44
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATF4 activating transcription factor 4
BMX BMX non-receptor tyrosine kinase
C2CD5 C2 calcium-dependent domain containing 5
CDC37 cell division cycle 37
CDC42 cell division cycle 42
CDKL5 cyclin-dependent kinase-like 5
CFL1 cofilin 1 (non-muscle)
CIB1 calcium and integrin binding 1 (calmyrin)
CLASP2 cytoplasmic linker associated protein 2
CNTNAP2 contactin associated protein-like 2
CSPG4 chondroitin sulfate proteoglycan 4
DDN dendrin
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DIAPH1 diaphanous-related formin 1
DLC1 DLC1 Rho GTPase activating protein
DPP4 dipeptidyl-peptidase 4
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHA2 EPH receptor A2
EPS8 epidermal growth factor receptor pathway substrate 8
EPS8L1 EPS8-like 1
EPS8L2 EPS8-like 2
EZR ezrin
FAP fibroblast activation protein, alpha
FERMT1 fermitin family member 1
FERMT2 fermitin family member 2
FGD2 FYVE, RhoGEF and PH domain containing 2
FGD5 FYVE, RhoGEF and PH domain containing 5
FGR FGR proto-oncogene, Src family tyrosine kinase
GABARAPL1 GABA(A) receptor-associated protein like 1
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GPER1 G protein-coupled estrogen receptor 1
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
INPP5K inositol polyphosphate-5-phosphatase K
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA8 integrin, alpha 8
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KANK1 KN motif and ankyrin repeat domains 1
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
LAMP5 lysosomal-associated membrane protein family, member 5
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
MACF1 microtubule-actin crosslinking factor 1
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MYO1D myosin ID
MYO1G myosin IG
MYO6 myosin VI
NCKAP1 NCK-associated protein 1
NF2 neurofibromin 2 (merlin)
NME1 NME/NM23 nucleoside diphosphate kinase 1
OPRD1 opioid receptor, delta 1
OPRM1 opioid receptor, mu 1
PACSIN1 protein kinase C and casein kinase substrate in neurons 1
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PALM paralemmin
PDE4A phosphodiesterase 4A, cAMP-specific
PDE9A phosphodiesterase 9A
PDPN podoplanin
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLA2G4F phospholipase A2, group IVF
PLEK pleckstrin
PLEK2 pleckstrin 2
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PTPRJ protein tyrosine phosphatase, receptor type, J
PTPRK protein tyrosine phosphatase, receptor type, K
RAB34 RAB34, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila)
RPS3 ribosomal protein S3
SCIMP SLP adaptor and CSK interacting membrane protein
SGCE sarcoglycan, epsilon
SH3YL1 SH3 and SYLF domain containing 1
SHISA9 shisa family member 9
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SNTG1 syntrophin, gamma 1
SPATA13 spermatogenesis associated 13
SPRY2 sprouty homolog 2 (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
SPTBN1 spectrin, beta, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SYNE2 spectrin repeat containing, nuclear envelope 2
TACR3 tachykinin receptor 3
TESC tescalcin
THEM4 thioesterase superfamily member 4
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLN1 talin 1
TPM1 tropomyosin 1 (alpha)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TWF1 twinfilin actin binding protein 1
VASP vasodilator-stimulated phosphoprotein
WLS wntless Wnt ligand secretion mediator
WWC1 WW and C2 domain containing 1