leading edge membrane Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The portion of the plasma membrane surrounding the leading edge of a motile cell. (Gene Ontology, GO_0031256)
Similar Terms
Downloads & Tools

Genes

98 proteins localized to the leading edge membrane cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.663342
CIB1 calcium and integrin binding 1 (calmyrin) 0.663342
ADGRE2 adhesion G protein-coupled receptor E2 0.663342
PDE4A phosphodiesterase 4A, cAMP-specific 0.663342
PTPRK protein tyrosine phosphatase, receptor type, K 0.663342
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.663342
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 0.663342
PDE9A phosphodiesterase 9A 0.663342
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.663342
AMPH amphiphysin 0.663342
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 0.663342
INPP5K inositol polyphosphate-5-phosphatase K 0.663342
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.663342
MACF1 microtubule-actin crosslinking factor 1 0.663342
CDC42 cell division cycle 42 0.663342
FERMT1 fermitin family member 1 0.663342
WWC1 WW and C2 domain containing 1 0.663342
NF2 neurofibromin 2 (merlin) 0.663342
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.663342
SNTG1 syntrophin, gamma 1 0.663342
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.663342
CLASP2 cytoplasmic linker associated protein 2 0.663342
SH3YL1 SH3 and SYLF domain containing 1 0.663342
KANK1 KN motif and ankyrin repeat domains 1 0.663342
SCIMP SLP adaptor and CSK interacting membrane protein 0.663342
FAP fibroblast activation protein, alpha 0.663342
RPS3 ribosomal protein S3 0.663342
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.663342
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.663342
EPHA2 EPH receptor A2 0.663342
AIF1 allograft inflammatory factor 1 0.663342
SPATA13 spermatogenesis associated 13 0.663342
ARHGAP44 Rho GTPase activating protein 44 0.663342
DPP4 dipeptidyl-peptidase 4 0.663342
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 0.663342
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 0.663342
ITGAV integrin, alpha V 0.663342
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.663342
ANTXR1 anthrax toxin receptor 1 0.663342
SYNE2 spectrin repeat containing, nuclear envelope 2 0.663342
APC adenomatous polyposis coli 0.663342
SYNE1 spectrin repeat containing, nuclear envelope 1 0.663342
MYO6 myosin VI 0.663342
PLEK2 pleckstrin 2 0.663342
BMX BMX non-receptor tyrosine kinase 0.663342
DIAPH1 diaphanous-related formin 1 0.663342
VASP vasodilator-stimulated phosphoprotein 0.663342
C2CD5 C2 calcium-dependent domain containing 5 0.663342
ARF4 ADP-ribosylation factor 4 0.237908
APC2 adenomatosis polyposis coli 2 0.237908
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.237908
CNTNAP2 contactin associated protein-like 2 0.237908
EPS8L1 EPS8-like 1 0.237908
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 0.237908
EPS8L2 EPS8-like 2 0.237908
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.237908
SHISA9 shisa family member 9 0.237908
SGCE sarcoglycan, epsilon 0.237908
LAMP5 lysosomal-associated membrane protein family, member 5 0.237908
GPER1 G protein-coupled estrogen receptor 1 0.237908
PLEK pleckstrin 0.237908
TPM1 tropomyosin 1 (alpha) 0.237908
EPS8 epidermal growth factor receptor pathway substrate 8 0.237908
FZD3 frizzled class receptor 3 0.098109
FZD7 frizzled class receptor 7 0.098109
FZD2 frizzled class receptor 2 0.098109
FZD1 frizzled class receptor 1 0.098109
FZD6 frizzled class receptor 6 0.098109
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 0.098109
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.098109
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.098109
SPTBN1 spectrin, beta, non-erythrocytic 1 0.098109
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 0.098109
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.03318
ITGA8 integrin, alpha 8 0.03318
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.03318
TACR3 tachykinin receptor 3 0.03318
GABARAPL1 GABA(A) receptor-associated protein like 1 0.03318
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.03318
EPB41L5 erythrocyte membrane protein band 4.1 like 5 0.03318
CDKL5 cyclin-dependent kinase-like 5 0.03318
CDC37 cell division cycle 37 0.03318
FGR FGR proto-oncogene, Src family tyrosine kinase 0.03318
PALM paralemmin 0.03318
ADORA1 adenosine A1 receptor 0.03318
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 0.03318
ATF4 activating transcription factor 4 0.03318
MYO1D myosin ID 0.03318
OPRD1 opioid receptor, delta 1 0.03318
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 0.03318
ANK1 ankyrin 1, erythrocytic 0.03318
RHOA ras homolog family member A 0.03318
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 0.03318
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 0.03318
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.03318
TWF1 twinfilin actin binding protein 1 0.03318
PLA2G4F phospholipase A2, group IVF 0.03318
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.03318