late endosome Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center. (Gene Ontology, GO_0005770)
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Genes

152 proteins localized to the late endosome cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
KIAA0368 KIAA0368 0.663342
VAMP8 vesicle-associated membrane protein 8 0.663342
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 0.663342
SQSTM1 sequestosome 1 0.663342
MICALL1 MICAL-like 1 0.663342
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) 0.663342
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 0.663342
UNC13D unc-13 homolog D (C. elegans) 0.663342
BACE1 beta-site APP-cleaving enzyme 1 0.663342
RAB14 RAB14, member RAS oncogene family 0.663342
ATG9A autophagy related 9A 0.663342
TSG101 tumor susceptibility 101 0.663342
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 0.663342
MITD1 MIT, microtubule interacting and transport, domain containing 1 0.663342
PARM1 prostate androgen-regulated mucin-like protein 1 0.663342
CD63 CD63 molecule 0.663342
STEAP3 STEAP family member 3, metalloreductase 0.663342
MAP2K2 mitogen-activated protein kinase kinase 2 0.663342
MAP2K1 mitogen-activated protein kinase kinase 1 0.663342
SNF8 SNF8, ESCRT-II complex subunit 0.663342
CLCN3 chloride channel, voltage-sensitive 3 0.663342
HLA-DRB3 major histocompatibility complex, class II, DR beta 3 0.663342
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.663342
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.663342
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.663342
PMEL premelanosome protein 0.663342
UVRAG UV radiation resistance associated 0.663342
MCOLN1 mucolipin 1 0.663342
CD1E CD1e molecule 0.663342
RAB9A RAB9A, member RAS oncogene family 0.663342
IFITM3 interferon induced transmembrane protein 3 0.663342
ARL8B ADP-ribosylation factor-like 8B 0.663342
ARL8A ADP-ribosylation factor-like 8A 0.663342
LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 0.663342
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 0.663342
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.663342
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.663342
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 0.663342
VPS33B vacuolar protein sorting 33 homolog B (yeast) 0.663342
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) 0.663342
TMEM192 transmembrane protein 192 0.663342
AP1AR adaptor-related protein complex 1 associated regulatory protein 0.663342
TMEM106B transmembrane protein 106B 0.663342
AP5M1 adaptor-related protein complex 5, mu 1 subunit 0.663342
STARD3 StAR-related lipid transfer (START) domain containing 3 0.663342
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 0.663342
HTT huntingtin 0.663342
AP5S1 adaptor-related protein complex 5, sigma 1 subunit 0.663342
OSBPL1A oxysterol binding protein-like 1A 0.663342
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.663342
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 0.663342
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 0.663342
RILP Rab interacting lysosomal protein 0.663342
RAB11A RAB11A, member RAS oncogene family 0.663342
RAB11B RAB11B, member RAS oncogene family 0.663342
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.663342
HLA-DRA major histocompatibility complex, class II, DR alpha 0.663342
TMEM9 transmembrane protein 9 0.663342
TPT1 tumor protein, translationally-controlled 1 0.663342
IGF2R insulin-like growth factor 2 receptor 0.663342
KIAA0226 KIAA0226 0.663342
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 0.663342
CXCR4 chemokine (C-X-C motif) receptor 4 0.663342
FYCO1 FYVE and coiled-coil domain containing 1 0.663342
RAP1A RAP1A, member of RAS oncogene family 0.663342
LDLR low density lipoprotein receptor 0.663342
NDFIP2 Nedd4 family interacting protein 2 0.663342
TMEM59 transmembrane protein 59 0.663342
MAPK3 mitogen-activated protein kinase 3 0.663342
LAMP2 lysosomal-associated membrane protein 2 0.663342
MAPK1 mitogen-activated protein kinase 1 0.663342
VTI1B vesicle transport through interaction with t-SNAREs 1B 0.663342
CTNS cystinosin, lysosomal cystine transporter 0.663342
TMEM165 transmembrane protein 165 0.663342
PCSK9 proprotein convertase subtilisin/kexin type 9 0.663342
ATP7B ATPase, Cu++ transporting, beta polypeptide 0.663342
MTM1 myotubularin 1 0.663342
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.663342
RAB27A RAB27A, member RAS oncogene family 0.663342
RAB27B RAB27B, member RAS oncogene family 0.663342
STARD3NL STARD3 N-terminal like 0.663342
ATP7A ATPase, Cu++ transporting, alpha polypeptide 0.663342
TF transferrin 0.663342
LAMP1 lysosomal-associated membrane protein 1 0.663342
TICAM2 toll-like receptor adaptor molecule 2 0.663342
RAB7A RAB7A, member RAS oncogene family 0.663342
CLN3 ceroid-lipofuscinosis, neuronal 3 0.663342
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 0.663342
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae) 0.663342
SNX16 sorting nexin 16 0.663342
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 0.663342
RHOB ras homolog family member B 0.663342
HLA-DMA major histocompatibility complex, class II, DM alpha 0.663342
FIG4 FIG4 phosphoinositide 5-phosphatase 0.237908
PIKFYVE phosphoinositide kinase, FYVE finger containing 0.237908
ANXA8L1 annexin A8-like 1 0.237908
ANXA8 annexin A8 0.237908
ANXA6 annexin A6 0.237908
CD79A CD79a molecule, immunoglobulin-associated alpha 0.237908
CYB561A3 cytochrome b561 family, member A3 0.237908
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.237908
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.237908
KIDINS220 kinase D-interacting substrate, 220kDa 0.237908
MVB12B multivesicular body subunit 12B 0.237908
CRHBP corticotropin releasing hormone binding protein 0.237908
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.237908
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 0.237908
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.237908
RNF13 ring finger protein 13 0.237908
ANXA2 annexin A2 0.237908
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 0.237908
NBR1 neighbor of BRCA1 gene 1 0.237908
SLC30A2 solute carrier family 30 (zinc transporter), member 2 0.237908
SLC30A3 solute carrier family 30 (zinc transporter), member 3 0.237908
SLC30A4 solute carrier family 30 (zinc transporter), member 4 0.237908
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 0.237908
ZP3 zona pellucida glycoprotein 3 (sperm receptor) 0.237908
VAC14 Vac14 homolog (S. cerevisiae) 0.237908
VAMP7 vesicle-associated membrane protein 7 0.237908
CHID1 chitinase domain containing 1 0.237908
VAMP5 vesicle-associated membrane protein 5 0.098109
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 0.098109
SDF4 stromal cell derived factor 4 0.098109
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 0.03318
CST3 cystatin C 0.03318
LGMN legumain 0.03318
SFTPC surfactant protein C 0.03318
DERL2 derlin 2 0.03318
DERL1 derlin 1 0.03318
DDIT3 DNA-damage-inducible transcript 3 0.03318
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.03318
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 0.03318
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 0.03318
TTPA tocopherol (alpha) transfer protein 0.03318
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.03318
CRHR1 corticotropin releasing hormone receptor 1 0.03318
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 0.03318
SLA2 Src-like-adaptor 2 0.03318
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha 0.03318
STX8 syntaxin 8 0.03318
APOE apolipoprotein E 0.03318
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 0.03318
SLC31A2 solute carrier family 31 (copper transporter), member 2 0.03318
ACPP acid phosphatase, prostate 0.03318
SLC31A1 solute carrier family 31 (copper transporter), member 1 0.03318
M6PR mannose-6-phosphate receptor (cation dependent) 0.03318
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 0.03318
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 0.03318
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) 0.03318
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.03318
SPPL2A signal peptide peptidase like 2A 0.03318
GJA1 gap junction protein, alpha 1, 43kDa 0.03318