large granular lymphocyte Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description A type of white blood cell that contains granules with enzymes that can kill tumor cells or microbial cells. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004717)
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Genes

692 proteins co-occuring with the tissue large granular lymphocyte in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
NCAM1 neural cell adhesion molecule 1 3.90776
KLRK1 killer cell lectin-like receptor subfamily K, member 1 3.36306
CD4 CD4 molecule 3.29771
IL2 interleukin 2 3.16615
B3GAT1 beta-1,3-glucuronyltransferase 1 3.07091
PRF1 perforin 1 (pore forming protein) 3.06439
KLRC1 killer cell lectin-like receptor subfamily C, member 1 3.04068
KLRD1 killer cell lectin-like receptor subfamily D, member 1 3.0151
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1 2.96427
NCR1 natural cytotoxicity triggering receptor 1 2.92461
HLA-B major histocompatibility complex, class I, B 2.86897
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 2.60756
KLRB1 killer cell lectin-like receptor subfamily B, member 1 2.55384
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 2.52742
CD19 CD19 molecule 2.51592
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 2.49693
HLA-C major histocompatibility complex, class I, C 2.44687
CD69 CD69 molecule 2.41587
MICA MHC class I polypeptide-related sequence A 2.35865
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 2.35696
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 2.35248
IFNA1 interferon, alpha 1 2.33239
KLRC2 killer cell lectin-like receptor subfamily C, member 2 2.32905
HLA-E major histocompatibility complex, class I, E 2.32738
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 2.32128
CD226 CD226 molecule 2.19664
IL15 interleukin 15 2.16867
HLA-A major histocompatibility complex, class I, A 2.07921
HLA-G major histocompatibility complex, class I, G 2.07547
MICB MHC class I polypeptide-related sequence B 2.05407
CD244 CD244 molecule, natural killer cell receptor 2B4 2.04926
CD7 CD7 molecule 2.00119
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 1.99853
ULBP1 UL16 binding protein 1 1.98949
GLIS2 GLIS family zinc finger 2 1.95882
TYROBP TYRO protein tyrosine kinase binding protein 1.95882
LAMP1 lysosomal-associated membrane protein 1 1.95829
TNF tumor necrosis factor 1.95566
IL2RA interleukin 2 receptor, alpha 1.94673
ULBP2 UL16 binding protein 2 1.9462
GNLY granulysin 1.94201
CD5 CD5 molecule 1.89565
RAE1 ribonucleic acid export 1 1.88995
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.88477
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 1.87805
CD34 CD34 molecule 1.84658
FASLG Fas ligand (TNF superfamily, member 6) 1.84196
IL18 interleukin 18 1.8026
CD1D CD1d molecule 1.75574
UNK unkempt family zinc finger 1.71738
KLRF1 killer cell lectin-like receptor subfamily F, member 1 1.71092
CD48 CD48 molecule 1.70097
ULBP3 UL16 binding protein 3 1.6955
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 1.69251
SH2D1A SH2 domain containing 1A 1.68952
TRAC T cell receptor alpha constant 1.65407
CD27 CD27 molecule 1.65357
CD38 CD38 molecule 1.65257
THY1 Thy-1 cell surface antigen 1.64857
ICAM1 intercellular adhesion molecule 1 1.64757
CXCL10 chemokine (C-X-C motif) ligand 10 1.63606
CXCR3 chemokine (C-X-C motif) receptor 3 1.62207
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.62058
KLRG1 killer cell lectin-like receptor subfamily G, member 1 1.60962
STAC SH3 and cysteine rich domain 1.59969
CD79A CD79a molecule, immunoglobulin-associated alpha 1.58043
CD33 CD33 molecule 1.57454
RAG2 recombination activating gene 2 1.56964
STAT4 signal transducer and activator of transcription 4 1.55698
IL21 interleukin 21 1.55309
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.55164
SLAMF6 SLAM family member 6 1.54971
SIGLEC7 sialic acid binding Ig-like lectin 7 1.53814
DHDH dihydrodiol dehydrogenase (dimeric) 1.52045
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.49726
AK5 adenylate kinase 5 1.49585
CD247 CD247 molecule 1.49349
TLR9 toll-like receptor 9 1.47522
CD40 CD40 molecule, TNF receptor superfamily member 5 1.46309
TBX21 T-box 21 1.45378
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 1.44543
CD58 CD58 molecule 1.44079
UEVLD UEV and lactate/malate dehyrogenase domains 1.44079
CXCL9 chemokine (C-X-C motif) ligand 9 1.43107
B2M beta-2-microglobulin 1.42968
UNC13D unc-13 homolog D (C. elegans) 1.42737
TLR3 toll-like receptor 3 1.42691
IL1B interleukin 1, beta 1.41999
FOXP3 forkhead box P3 1.41906
IL10 interleukin 10 1.41307
SPG20 spastic paraplegia 20 (Troyer syndrome) 1.40064
FLT3 fms-related tyrosine kinase 3 1.39972
IL2RG interleukin 2 receptor, gamma 1.39651
CCL3 chemokine (C-C motif) ligand 3 1.37408
IL7R interleukin 7 receptor 1.37134
CD86 CD86 molecule 1.36906
STX11 syntaxin 11 1.36587
CD80 CD80 molecule 1.35904
TRIM45 tripartite motif containing 45 1.3554
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 1.35268
PTPRC protein tyrosine phosphatase, receptor type, C 1.34224
TFRC transferrin receptor 1.33817
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 1.33364
CCR7 chemokine (C-C motif) receptor 7 1.33274
RAG1 recombination activating gene 1 1.33003
CD40LG CD40 ligand 1.32687
JAK3 Janus kinase 3 1.32235
TGFB1 transforming growth factor, beta 1 1.32055
IL4 interleukin 4 1.31514
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 1.31289
IFNG interferon, gamma 1.31244
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.31198
CD68 CD68 molecule 1.30523
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 1.29669
KLRC3 killer cell lectin-like receptor subfamily C, member 3 1.28009
KLRC4 killer cell lectin-like receptor subfamily C, member 4 1.27785
CD276 CD276 molecule 1.27471
NELFCD negative elongation factor complex member C/D 1.26889
SORBS1 sorbin and SH3 domain containing 1 1.26039
STAT1 signal transducer and activator of transcription 1, 91kDa 1.25771
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.23361
SYK spleen tyrosine kinase 1.23272
GZMM granzyme M (lymphocyte met-ase 1) 1.22915
LCK LCK proto-oncogene, Src family tyrosine kinase 1.22336
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 1.22113
LILRP1 leukocyte immunoglobulin-like receptor pseudogene 1 1.2198
GZMK granzyme K (granzyme 3; tryptase II) 1.21579
TIGIT T cell immunoreceptor with Ig and ITIM domains 1.21579
IL6 interleukin 6 1.2149
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.21179
CD44 CD44 molecule (Indian blood group) 1.20778
CD8A CD8a molecule 1.206
IFNA2 interferon, alpha 2 1.20422
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 1.19489
CD160 CD160 molecule 1.19178
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 1.17935
CD2 CD2 molecule 1.16959
AFF2 AF4/FMR2 family, member 2 1.16737
TLR4 toll-like receptor 4 1.16382
IL22 interleukin 22 1.15673
NFIL3 nuclear factor, interleukin 3 regulated 1.13944
RP9 retinitis pigmentosa 9 (autosomal dominant) 1.13545
PGM3 phosphoglucomutase 3 1.13412
CD96 CD96 molecule 1.13324
CD84 CD84 molecule 1.11376
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.11287
CCL2 chemokine (C-C motif) ligand 2 1.10668
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.10358
TLR7 toll-like receptor 7 1.10004
IFNB1 interferon, beta 1, fibroblast 1.09916
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.09562
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 1.09253
TLR2 toll-like receptor 2 1.08148
CLEC2D C-type lectin domain family 2, member D 1.07794
OAT ornithine aminotransferase 1.0775
CXCL11 chemokine (C-X-C motif) ligand 11 1.07265
SLAMF1 signaling lymphocytic activation molecule family member 1 1.07176
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 1.05941
IL1A interleukin 1, alpha 1.05853
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 1.04577
VAV1 vav 1 guanine nucleotide exchange factor 1.04357
IL7 interleukin 7 1.03566
IDO1 indoleamine 2,3-dioxygenase 1 1.03127
CCL5 chemokine (C-C motif) ligand 5 1.03083
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.02557
EOMES eomesodermin 1.02118
IL12RB1 interleukin 12 receptor, beta 1 1.019
MYD88 myeloid differentiation primary response 88 1.01593
STXBP2 syntaxin binding protein 2 1.01549
POMC proopiomelanocortin 1.01287
GATA3 GATA binding protein 3 1.012
FYN FYN proto-oncogene, Src family tyrosine kinase 1.00676
CD6 CD6 molecule 0.993684
FCHSD2 FCH and double SH3 domains 2 0.992379
CCL4 chemokine (C-C motif) ligand 4 0.988032
CTSW cathepsin W 0.987162
CCL13 chemokine (C-C motif) ligand 13 0.983254
LTA lymphotoxin alpha 0.981953
PDLIM7 PDZ and LIM domain 7 (enigma) 0.971984
RAET1E retinoic acid early transcript 1E 0.971984
CD22 CD22 molecule 0.971552
HSPA4 heat shock 70kDa protein 4 0.96809
CD83 CD83 molecule 0.967225
IL12B interleukin 12B 0.96636
RNF19B ring finger protein 19B 0.96636
ERBB2 erb-b2 receptor tyrosine kinase 2 0.95729
CD52 CD52 molecule 0.955565
NKTR natural killer cell triggering receptor 0.952116
CCL22 chemokine (C-C motif) ligand 22 0.951254
IL32 interleukin 32 0.950823
CD8B CD8b molecule 0.941785
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 0.940066
FCRL6 Fc receptor-like 6 0.937488
OSTC oligosaccharyltransferase complex subunit (non-catalytic) 0.931051
SELL selectin L 0.928906
SIGLEC9 sialic acid binding Ig-like lectin 9 0.924623
SLAMF7 SLAM family member 7 0.918206
PVR poliovirus receptor 0.917779
NCR3 natural cytotoxicity triggering receptor 3 0.908387
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.902424
CD70 CD70 molecule 0.899445
RAET1G retinoic acid early transcript 1G 0.895195
LY9 lymphocyte antigen 9 0.893496
LAG3 lymphocyte-activation gene 3 0.888405
LAT linker for activation of T cells 0.888405
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.885438
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.883744
VCAM1 vascular cell adhesion molecule 1 0.880781
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.876129
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.868951
CLEC2B C-type lectin domain family 2, member B 0.867686
IL27RA interleukin 27 receptor, alpha 0.867263
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.856732
CARD17 caspase recruitment domain family, member 17 0.850845
CCR2 chemokine (C-C motif) receptor 2 0.850425
IGHV3-30 immunoglobulin heavy variable 3-30 0.850425
IRF1 interferon regulatory factor 1 0.845805
CRP C-reactive protein, pentraxin-related 0.844545
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) 0.843706
CXCL12 chemokine (C-X-C motif) ligand 12 0.842447
CD81 CD81 molecule 0.837833
TYK2 tyrosine kinase 2 0.830709
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.828616
IL18RAP interleukin 18 receptor accessory protein 0.821502
IFNL3 interferon, lambda 3 0.821085
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 0.818994
IL2RB interleukin 2 receptor, beta 0.813979
CMKLR1 chemerin chemokine-like receptor 1 0.813144
LYST lysosomal trafficking regulator 0.810221
CCR1 chemokine (C-C motif) receptor 1 0.806465
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.80563
WAS Wiskott-Aldrich syndrome 0.792709
TLR8 toll-like receptor 8 0.790628
RAET1L retinoic acid early transcript 1L 0.790212
NKG7 natural killer cell granule protein 7 0.788964
ANXA5 annexin A5 0.787716
TICAM1 toll-like receptor adaptor molecule 1 0.785635
FER fer (fps/fes related) tyrosine kinase 0.78522
RORC RAR-related orphan receptor C 0.783557
IL18BP interleukin 18 binding protein 0.781478
EBAG9 estrogen receptor binding site associated, antigen, 9 0.779401
CCR6 chemokine (C-C motif) receptor 6 0.778986
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.77193
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 0.7711
KITLG KIT ligand 0.769027
ALK anaplastic lymphoma receptor tyrosine kinase 0.764468
TSPO translocator protein (18kDa) 0.763226
NCR2 natural cytotoxicity triggering receptor 2 0.757018
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.754537
JAK2 Janus kinase 2 0.750405
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.749579
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 0.747102
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.742976
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.742152
ASRGL1 asparaginase like 1 0.738854
CD1C CD1c molecule 0.736382
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.73062
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.729797
CD3D CD3d molecule, delta (CD3-TCR complex) 0.726918
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.726507
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.724453
FN1 fibronectin 1 0.722809
CD163 CD163 molecule 0.719524
HLA-F major histocompatibility complex, class I, F 0.719113
HCG4P11 HLA complex group 4 pseudogene 11 0.719113
HMBOX1 homeobox containing 1 0.718703
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.717061
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.713779
NCCRP1 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) 0.712139
TREM1 triggering receptor expressed on myeloid cells 1 0.712139
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.70968
DNTT DNA nucleotidylexotransferase 0.706812
IL3 interleukin 3 0.704764
S1PR5 sphingosine-1-phosphate receptor 5 0.702308
TAPBP TAP binding protein (tapasin) 0.701899
FHL2 four and a half LIM domains 2 0.699853
RAB27A RAB27A, member RAS oncogene family 0.699853
ICAM2 intercellular adhesion molecule 2 0.696989
C1R complement component 1, r subcomponent 0.696989
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.694946
SELE selectin E 0.694537
PTPRD protein tyrosine phosphatase, receptor type, D 0.692493
IRF6 interferon regulatory factor 6 0.689634
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.688817
HRAS Harvey rat sarcoma viral oncogene homolog 0.685959
CXCR1 chemokine (C-X-C motif) receptor 1 0.684327
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 0.683103
CLEC4C C-type lectin domain family 4, member C 0.683103
SCYL1 SCY1-like 1 (S. cerevisiae) 0.682695
IFNAR2 interferon (alpha, beta and omega) receptor 2 0.677395
CCL21 chemokine (C-C motif) ligand 21 0.674543
BST2 bone marrow stromal cell antigen 2 0.673321
CRTAM cytotoxic and regulatory T cell molecule 0.672913
HIST1H1B histone cluster 1, H1b 0.666809
JAK1 Janus kinase 1 0.665182
EGFR epidermal growth factor receptor 0.663149
PAX5 paired box 5 0.659897
TP53 tumor protein p53 0.659897
BAG6 BCL2-associated athanogene 6 0.658678
CD59 CD59 molecule, complement regulatory protein 0.657054
PLCG1 phospholipase C, gamma 1 0.655024
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.654618
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.653807
CCL17 chemokine (C-C motif) ligand 17 0.647316
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 0.646911
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.644074
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.642454
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.640428
IL15RA interleukin 15 receptor, alpha 0.636785
MAG myelin associated glycoprotein 0.63638
CLEC4A C-type lectin domain family 4, member A 0.635167
CD300A CD300a molecule 0.633953
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 0.629506
EPCAM epithelial cell adhesion molecule 0.627485
TLR1 toll-like receptor 1 0.624254
LTF lactotransferrin 0.623043
ELF4 E74-like factor 4 (ets domain transcription factor) 0.622639
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.619814
IRF3 interferon regulatory factor 3 0.618603
SH2B3 SH2B adaptor protein 3 0.617393
CCL4L2 chemokine (C-C motif) ligand 4-like 2 0.612555
CCL4L1 chemokine (C-C motif) ligand 4-like 1 0.606514
DERL2 derlin 2 0.606514
HIST1H1D histone cluster 1, H1d 0.604099
CXCR6 chemokine (C-X-C motif) receptor 6 0.599273
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.597666
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.597263
DLL1 delta-like 1 (Drosophila) 0.595255
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.591641
HMGB1 high mobility group box 1 0.590839
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.589234
MRAP melanocortin 2 receptor accessory protein 0.589234
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.587629
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 0.585625
USH2A Usher syndrome 2A (autosomal recessive, mild) 0.584422
LYZ lysozyme 0.580818
CTRL chymotrypsin-like 0.576415
LAT2 linker for activation of T cells family, member 2 0.576415
IFNA7 interferon, alpha 7 0.574816
ALB albumin 0.566828
FGL2 fibrinogen-like 2 0.560847
CD209 CD209 molecule 0.559652
FGFBP2 fibroblast growth factor binding protein 2 0.558856
TF transferrin 0.555671
CD9 CD9 molecule 0.554876
IL13 interleukin 13 0.554876
CDK2 cyclin-dependent kinase 2 0.554876
XCL1 chemokine (C motif) ligand 1 0.553286
IFNK interferon, kappa 0.55249
CCL19 chemokine (C-C motif) ligand 19 0.549709
CTSC cathepsin C 0.543756
PRL prolactin 0.541377
CXCL8 chemokine (C-X-C motif) ligand 8 0.540981
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.540188
MUC1 mucin 1, cell surface associated 0.540188
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.537812
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 0.537021
MPO myeloperoxidase 0.533065
DYNLT1 dynein, light chain, Tctex-type 1 0.532274
SECTM1 secreted and transmembrane 1 0.528719
KCTD9 potassium channel tetramerization domain containing 9 0.527928
SLC25A30 solute carrier family 25, member 30 0.52635
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.52556
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 0.519253
FCAR Fc fragment of IgA receptor 0.519253
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.51571
VAMP7 vesicle-associated membrane protein 7 0.509027
GRB2 growth factor receptor-bound protein 2 0.505495
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.499223
ACPP acid phosphatase, prostate 0.496874
CLEC12A C-type lectin domain family 12, member A 0.494918
CCR9 chemokine (C-C motif) receptor 9 0.492963
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.492963
CCL7 chemokine (C-C motif) ligand 7 0.492182
PRDM1 PR domain containing 1, with ZNF domain 0.489057
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.488276
CCL8 chemokine (C-C motif) ligand 8 0.487886
CD46 CD46 molecule, complement regulatory protein 0.479702
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.479312
BCL10 B-cell CLL/lymphoma 10 0.478923
GNG8 guanine nucleotide binding protein (G protein), gamma 8 0.474258
HRH2 histamine receptor H2 0.473869
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 0.472704
ATM ATM serine/threonine kinase 0.472704
SNX27 sorting nexin family member 27 0.468048
CCRL2 chemokine (C-C motif) receptor-like 2 0.463013
MMP10 matrix metallopeptidase 10 0.458759
KRAS Kirsten rat sarcoma viral oncogene homolog 0.4576
CCR3 chemokine (C-C motif) receptor 3 0.456442
PAX2 paired box 2 0.454512
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.454512
CD37 CD37 molecule 0.452198
CD24 CD24 molecule 0.449116
C3 complement component 3 0.447192
VEGFA vascular endothelial growth factor A 0.446422
IRF2 interferon regulatory factor 2 0.445268
ICAM3 intercellular adhesion molecule 3 0.444884
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.444499
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 0.441426
PROM1 prominin 1 0.437205
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.436438
IL17A interleukin 17A 0.435672
CMA1 chymase 1, mast cell 0.435289
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.431843
IFIH1 interferon induced with helicase C domain 1 0.431843
IRF7 interferon regulatory factor 7 0.43146
BTLA B and T lymphocyte associated 0.430695
NOTCH1 notch 1 0.42993
LGALS9 lectin, galactoside-binding, soluble, 9 0.424199
IL10RA interleukin 10 receptor, alpha 0.422673
GATA2 GATA binding protein 2 0.422673
IFNA21 interferon, alpha 21 0.42191
HS3ST4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 0.421529
VAT1L vesicle amine transport 1-like 0.419623
BCL2L1 BCL2-like 1 0.417337
CSF3 colony stimulating factor 3 (granulocyte) 0.417337
HIST2H2AC histone cluster 2, H2ac 0.415434
FTL ferritin, light polypeptide 0.415434
CALR calreticulin 0.414673
HIST2H2AA3 histone cluster 2, H2aa3 0.414673
HIST2H2AA4 histone cluster 2, H2aa4 0.414673
SOCS1 suppressor of cytokine signaling 1 0.411631
FTH1 ferritin, heavy polypeptide 1 0.408212
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 0.405555
PAEP progestagen-associated endometrial protein 0.404797
IFNA17 interferon, alpha 17 0.404418
IL1RN interleukin 1 receptor antagonist 0.401765
SRGN serglycin 0.399114
SELPLG selectin P ligand 0.398735
HBA2 hemoglobin, alpha 2 0.397979
TLR5 toll-like receptor 5 0.3976
ADA adenosine deaminase 0.3976
DPP4 dipeptidyl-peptidase 4 0.397222
SPN sialophorin 0.395331
LYN LYN proto-oncogene, Src family tyrosine kinase 0.394953
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 0.394576
HBA1 hemoglobin, alpha 1 0.394197
CD300C CD300c molecule 0.393819
SEZ6L2 seizure related 6 homolog (mouse)-like 2 0.390044
INO80D INO80 complex subunit D 0.38665
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.385896
CD63 CD63 molecule 0.382884
MEX3C mex-3 RNA binding family member C 0.381755
NOS2 nitric oxide synthase 2, inducible 0.378748
S100A9 S100 calcium binding protein A9 0.378372
CXCR5 chemokine (C-X-C motif) receptor 5 0.377245
DOCK8 dedicator of cytokinesis 8 0.377245
JUN jun proto-oncogene 0.37687
NOG noggin 0.373493
CLEC3A C-type lectin domain family 3, member A 0.370496
LMNA lamin A/C 0.369373
CLPS colipase, pancreatic 0.368998
MCM4 minichromosome maintenance complex component 4 0.367502
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.366754
CD72 CD72 molecule 0.366381
ALPPL2 alkaline phosphatase, placental-like 2 0.366381
ALPL alkaline phosphatase, liver/bone/kidney 0.366007
ALPP alkaline phosphatase, placental 0.365633
CCL1 chemokine (C-C motif) ligand 1 0.365633
EDA ectodysplasin A 0.364513
CXCL14 chemokine (C-X-C motif) ligand 14 0.364139
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.362646
CNTN6 contactin 6 0.362273
WAPAL wings apart-like homolog (Drosophila) 0.362273
SIRPA signal-regulatory protein alpha 0.361901
IGHV5-51 immunoglobulin heavy variable 5-51 0.361527
GLB1 galactosidase, beta 1 0.361155
SLAMF8 SLAM family member 8 0.360782
CAT catalase 0.360782
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.360036
MARCH9 membrane-associated ring finger (C3HC4) 9 0.357802
ELANE elastase, neutrophil expressed 0.357058
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.356686
FGR FGR proto-oncogene, Src family tyrosine kinase 0.353712
IL18R1 interleukin 18 receptor 1 0.35334
BIRC5 baculoviral IAP repeat containing 5 0.352969
MUC16 mucin 16, cell surface associated 0.350743
LACE1 lactation elevated 1 0.347038
INS insulin 0.346298
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.345928
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 0.345188
BCR breakpoint cluster region 0.344818
VIL1 villin 1 0.344449
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.34371
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 0.34334
CLEC1A C-type lectin domain family 1, member A 0.342602
CLEC10A C-type lectin domain family 10, member A 0.341863
MMP9 matrix metallopeptidase 9 0.341863
CRH corticotropin releasing hormone 0.340757
SH2D2A SH2 domain containing 2A 0.340019
CCL20 chemokine (C-C motif) ligand 20 0.340019
SIRPB1 signal-regulatory protein beta 1 0.338545
IFT122 intraflagellar transport 122 0.337072
IFNE interferon, epsilon 0.337072
ADAM17 ADAM metallopeptidase domain 17 0.336336
LTB lymphotoxin beta (TNF superfamily, member 3) 0.335233
TGFB2 transforming growth factor, beta 2 0.33413
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 0.33413
FPR3 formyl peptide receptor 3 0.33413
HOXB4 homeobox B4 0.333763
IL21R interleukin 21 receptor 0.333396
CCDC130 coiled-coil domain containing 130 0.333396
IGF1 insulin-like growth factor 1 (somatomedin C) 0.331927
PMEL premelanosome protein 0.331927
CARS cysteinyl-tRNA synthetase 0.329361
TCHH trichohyalin 0.324605
FCRL1 Fc receptor-like 1 0.323509
PIBF1 progesterone immunomodulatory binding factor 1 0.323144
SH2D1B SH2 domain containing 1B 0.323144
CLNK cytokine-dependent hematopoietic cell linker 0.321685
RANGAP1 Ran GTPase activating protein 1 0.321685
ZBTB16 zinc finger and BTB domain containing 16 0.321685
PRDX1 peroxiredoxin 1 0.320956
CTSG cathepsin G 0.320227
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.320227
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.319134
DCLRE1C DNA cross-link repair 1C 0.318042
FAS Fas cell surface death receptor 0.316224
EBI3 Epstein-Barr virus induced 3 0.315861
MRC1 mannose receptor, C type 1 0.315135
LSM1 LSM1, U6 small nuclear RNA associated 0.311145
MPEG1 macrophage expressed 1 0.310421
C9 complement component 9 0.309335
MBP myelin basic protein 0.308612
RUNX3 runt-related transcription factor 3 0.308612
STAT5B signal transducer and activator of transcription 5B 0.306805
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.303919
KLRG2 killer cell lectin-like receptor subfamily G, member 2 0.302478
FCRL3 Fc receptor-like 3 0.302478
CLEC2L C-type lectin domain family 2, member L 0.301039
XCR1 chemokine (C motif) receptor 1 0.298883
KIF23 kinesin family member 23 0.297806
ISG20 interferon stimulated exonuclease gene 20kDa 0.297806
DCT dopachrome tautomerase 0.29673
TYRO3 TYRO3 protein tyrosine kinase 0.296372
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.295655
HSPA1L heat shock 70kDa protein 1-like 0.291722
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 0.291008
CXCL13 chemokine (C-X-C motif) ligand 13 0.289939
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 0.28887
CD53 CD53 molecule 0.288514
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.287092
FABP9 fatty acid binding protein 9, testis 0.285671
BAX BCL2-associated X protein 0.284962
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.282837
AXL AXL receptor tyrosine kinase 0.282837
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 0.28107
CD200 CD200 molecule 0.279659
CDC42 cell division cycle 42 0.277197
IL20RB interleukin 20 receptor beta 0.275794
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 0.274744
HUNK hormonally up-regulated Neu-associated kinase 0.274394
STAT5A signal transducer and activator of transcription 5A 0.274045
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.273696
BLNK B-cell linker 0.2723
SOD2 superoxide dismutase 2, mitochondrial 0.271604
FAM26F family with sequence similarity 26, member F 0.267791
MOG myelin oligodendrocyte glycoprotein 0.267446
AHR aryl hydrocarbon receptor 0.264353
CCR8 chemokine (C-C motif) receptor 8 0.263669
F2R coagulation factor II (thrombin) receptor 0.262986
PGR progesterone receptor 0.259929
RGL1 ral guanine nucleotide dissociation stimulator-like 1 0.25858
IRF5 interferon regulatory factor 5 0.258243
FPR2 formyl peptide receptor 2 0.256568
HDAC9 histone deacetylase 9 0.255234
ZAK sterile alpha motif and leucine zipper containing kinase AZK 0.253908
IFNA13 interferon, alpha 13 0.253908
CXCR2 chemokine (C-X-C motif) receptor 2 0.252261
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 0.251606
GFER growth factor, augmenter of liver regeneration 0.250301
PCNA proliferating cell nuclear antigen 0.250301
RHBDD3 rhomboid domain containing 3 0.247719
HOXA10 homeobox A10 0.243294
C5 complement component 5 0.242363
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 0.242054
SRSF11 serine/arginine-rich splicing factor 11 0.241438
TANK TRAF family member-associated NFKB activator 0.24052
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 0.239913
AIM1 absent in melanoma 1 0.239307
BTK Bruton agammaglobulinemia tyrosine kinase 0.238706
CARD11 caspase recruitment domain family, member 11 0.238108
KRT222 keratin 222, type II 0.23781
TOX thymocyte selection-associated high mobility group box 0.237513
FADD Fas (TNFRSF6)-associated via death domain 0.237216
CADM1 cell adhesion molecule 1 0.235457
DENND1B DENN/MADD domain containing 1B 0.234302
CD28 CD28 molecule 0.234302
IFNL2 interferon, lambda 2 0.232039
TARP TCR gamma alternate reading frame protein 0.232039
STXBP5 syntaxin binding protein 5 (tomosyn) 0.231206
THPO thrombopoietin 0.229299
LGALS7 lectin, galactoside-binding, soluble, 7 0.229032
CLEC1B C-type lectin domain family 1, member B 0.228497
MT1A metallothionein 1A 0.227186
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.225144
NR0B2 nuclear receptor subfamily 0, group B, member 2 0.224645
BCL2 B-cell CLL/lymphoma 2 0.223906
BCL6 B-cell CLL/lymphoma 6 0.223906
MIPEP mitochondrial intermediate peptidase 0.223906
PLAU plasminogen activator, urokinase 0.223662
RGS18 regulator of G-protein signaling 18 0.223298
CD1B CD1b molecule 0.223177
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 0.222938
ICK intestinal cell (MAK-like) kinase 0.220152
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 0.219707
TCF3 transcription factor 3 0.21883
TLR6 toll-like receptor 6 0.218186
PTK2B protein tyrosine kinase 2 beta 0.217974
CXCL2 chemokine (C-X-C motif) ligand 2 0.217762
PARP1 poly (ADP-ribose) polymerase 1 0.217139
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.216325
TRAFD1 TRAF-type zinc finger domain containing 1 0.214765
IL23A interleukin 23, alpha subunit p19 0.21365
IL27 interleukin 27 0.213471
PAPD7 PAP associated domain containing 7 0.213291
RGS8 regulator of G-protein signaling 8 0.212645
MARCH4 membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase 0.212413
RGS1 regulator of G-protein signaling 1 0.198614
TXN thioredoxin 0.198474
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 0.198178
ATL2 atlastin GTPase 2 0.197693
RGS5 regulator of G-protein signaling 5 0.197084
MMP25 matrix metallopeptidase 25 0.195102
SSB Sjogren syndrome antigen B (autoantigen La) 0.194201
CCL3L1 chemokine (C-C motif) ligand 3-like 1 0.194104
CD1E CD1e molecule 0.193149
FUT2 fucosyltransferase 2 (secretor status included) 0.192202
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.191858
CST7 cystatin F (leukocystatin) 0.190664
TARS threonyl-tRNA synthetase 0.18976
RGS2 regulator of G-protein signaling 2 0.189566
POPDC3 popeye domain containing 3 0.189417
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.182882
MIR363 microRNA 363 0.18202
MAPK4 mitogen-activated protein kinase 4 0.181532
TFDP1 transcription factor Dp-1 0.180165
CD2AP CD2-associated protein 0.179886
VAMP4 vesicle-associated membrane protein 4 0.179473
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 0.179359
MAPK12 mitogen-activated protein kinase 12 0.177903
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 0.17765
EVPL envoplakin 0.176779
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) 0.176622
FRS2 fibroblast growth factor receptor substrate 2 0.176223
IL12RB2 interleukin 12 receptor, beta 2 0.175875
NOD1 nucleotide-binding oligomerization domain containing 1 0.175709
IL4R interleukin 4 receptor 0.175091
EXOC2 exocyst complex component 2 0.173825
MIR26B microRNA 26b 0.173324
ASGR2 asialoglycoprotein receptor 2 0.172479
ASGR1 asialoglycoprotein receptor 1 0.171752
MIR146A microRNA 146a 0.171752
ITK IL2-inducible T-cell kinase 0.171022
FOXO3 forkhead box O3 0.17029
RALB v-ral simian leukemia viral oncogene homolog B 0.169826
NLRP3 NLR family, pyrin domain containing 3 0.169826
CORO1A coronin, actin binding protein, 1A 0.168172
SH3BP2 SH3-domain binding protein 2 0.166585
ZHX2 zinc fingers and homeoboxes 2 0.165709
PCDH15 protocadherin-related 15 0.163777
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.16122
CNTN5 contactin 5 0.161135
TMEM245 transmembrane protein 245 0.161051
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.158775
NOD2 nucleotide-binding oligomerization domain containing 2 0.158543
SHB Src homology 2 domain containing adaptor protein B 0.157212
PLXNB1 plexin B1 0.156072
ATG5 autophagy related 5 0.155869
NSF N-ethylmaleimide-sensitive factor 0.154054
GPR135 G protein-coupled receptor 135 0.153946
CTSA cathepsin A 0.153891
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.152025
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 0.151229
MMP2 matrix metallopeptidase 2 0.150942
ACTB actin, beta 0.150185
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.148872
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 0.148568
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.148082
ACTG1 actin gamma 1 0.147268
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.146956
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.146061
CRLF2 cytokine receptor-like factor 2 0.144823
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 0.144625
PRLR prolactin receptor 0.144427
GSTA3 glutathione S-transferase alpha 3 0.144427
CLEC5A C-type lectin domain family 5, member A 0.144295
GSTA4 glutathione S-transferase alpha 4 0.144097
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 0.144031
GSTA2 glutathione S-transferase alpha 2 0.144031
SAA1 serum amyloid A1 0.143963
HBE1 hemoglobin, epsilon 1 0.143895