large granular lymphocyte Gene Set

Dataset TISSUES Experimental Tissue Protein Expression Evidence Scores
Category proteomics
Type tissue
Description A type of white blood cell that contains granules with enzymes that can kill tumor cells or microbial cells. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004717)
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Genes

346 proteins highly expressed in the tissue large granular lymphocyte in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
SYNE2 spectrin repeat containing, nuclear envelope 2 3.10125
GCC1 GRIP and coiled-coil domain containing 1 3.10125
PDZD3 PDZ domain containing 3 3.10125
KCNG3 potassium channel, voltage gated modifier subfamily G, member 3 3.10125
TPR translocated promoter region, nuclear basket protein 3.10125
TRGC2 T cell receptor gamma constant 2 3.10125
CAMSAP1 calmodulin regulated spectrin-associated protein 1 3.10125
EXOC5 exocyst complex component 5 3.10125
NUMA1 nuclear mitotic apparatus protein 1 3.10125
IQGAP3 IQ motif containing GTPase activating protein 3 3.10125
NRIP1 nuclear receptor interacting protein 1 3.10125
GPI glucose-6-phosphate isomerase 3.10125
COQ10A coenzyme Q10 homolog A (S. cerevisiae) 3.10125
FAM92A1 family with sequence similarity 92, member A1 3.10125
FAM214A family with sequence similarity 214, member A 3.10125
RB1 retinoblastoma 1 3.10125
AHNAK AHNAK nucleoprotein 3.10125
KIF20B kinesin family member 20B 1.53602
RNF17 ring finger protein 17 1.53602
EIF3A eukaryotic translation initiation factor 3, subunit A 1.53602
PRPF8 pre-mRNA processing factor 8 1.53602
VCL vinculin 1.53602
CLTC clathrin, heavy chain (Hc) 1.53602
CLTCL1 clathrin, heavy chain-like 1 1.53602
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 1.53602
AMPD3 adenosine monophosphate deaminase 3 1.0758
DOCK6 dedicator of cytokinesis 6 1.0758
LRPPRC leucine-rich pentatricopeptide repeat containing 1.0758
PHLDB2 pleckstrin homology-like domain, family B, member 2 1.0758
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 1.0758
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) 1.0758
ANXA6 annexin A6 1.0758
EEA1 early endosome antigen 1 1.0758
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 1.0758
RNF41 ring finger protein 41, E3 ubiquitin protein ligase 1.0758
VCP valosin containing protein 1.0758
ATM ATM serine/threonine kinase 1.0758
LMNB2 lamin B2 1.0758
PTPRC protein tyrosine phosphatase, receptor type, C 1.0758
COPA coatomer protein complex, subunit alpha 1.0758
SPATA17 spermatogenesis associated 17 1.0758
ACTN1 actinin, alpha 1 1.0758
RAD50 RAD50 homolog (S. cerevisiae) 1.0758
SDF4 stromal cell derived factor 4 1.0758
IQGAP2 IQ motif containing GTPase activating protein 2 1.0758
IGF2R insulin-like growth factor 2 receptor 1.0758
IQGAP1 IQ motif containing GTPase activating protein 1 1.0758
EFTUD2 elongation factor Tu GTP binding domain containing 2 0.766457
NES nestin 0.766457
EHD3 EH-domain containing 3 0.766457
IER2 immediate early response 2 0.766457
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 0.766457
KRT25 keratin 25, type I 0.766457
LASP1 LIM and SH3 protein 1 0.766457
KRT24 keratin 24, type I 0.766457
KRT27 keratin 27, type I 0.766457
DTNB dystrobrevin, beta 0.766457
KRT26 keratin 26, type I 0.766457
PFDN5 prefoldin subunit 5 0.766457
EHD1 EH-domain containing 1 0.766457
IFITM1 interferon induced transmembrane protein 1 0.766457
RPS15A ribosomal protein S15a 0.766457
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 0.766457
GNLY granulysin 0.766457
RPS3A ribosomal protein S3A 0.766457
DDB1 damage-specific DNA binding protein 1, 127kDa 0.766457
JUND jun D proto-oncogene 0.766457
PDIA2 protein disulfide isomerase family A, member 2 0.766457
KIF23 kinesin family member 23 0.766457
PDIA3 protein disulfide isomerase family A, member 3 0.766457
PDIA4 protein disulfide isomerase family A, member 4 0.766457
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.766457
DPPA2 developmental pluripotency associated 2 0.766457
KRT28 keratin 28, type I 0.766457
APOBR apolipoprotein B receptor 0.766457
DAB2IP DAB2 interacting protein 0.766457
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 0.766457
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.766457
IARS isoleucyl-tRNA synthetase 0.766457
RPL27A ribosomal protein L27a 0.766457
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.766457
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.766457
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.766457
CCT8 chaperonin containing TCP1, subunit 8 (theta) 0.766457
LITAF lipopolysaccharide-induced TNF factor 0.766457
CORO1A coronin, actin binding protein, 1A 0.766457
MYOM2 myomesin 2 0.766457
CSE1L CSE1 chromosome segregation 1-like (yeast) 0.766457
TSC22D3 TSC22 domain family, member 3 0.766457
NKG7 natural killer cell granule protein 7 0.766457
MSN moesin 0.766457
CCL5 chemokine (C-C motif) ligand 5 0.766457
G6PD glucose-6-phosphate dehydrogenase 0.766457
RPL39 ribosomal protein L39 0.766457
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.766457
RPL34 ribosomal protein L34 0.766457
RPL35 ribosomal protein L35 0.766457
NUP210L nucleoporin 210kDa-like 0.766457
RPL32 ribosomal protein L32 0.766457
RPL30 ribosomal protein L30 0.766457
KTN1 kinectin 1 (kinesin receptor) 0.766457
RPLP1 ribosomal protein, large, P1 0.766457
RPLP2 ribosomal protein, large, P2 0.766457
MYD88 myeloid differentiation primary response 88 0.766457
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.766457
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.766457
SFPQ splicing factor proline/glutamine-rich 0.766457
CCND3 cyclin D3 0.766457
RPS27A ribosomal protein S27a 0.766457
SH3BP1 SH3-domain binding protein 1 0.766457
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.766457
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.766457
HSPA8 heat shock 70kDa protein 8 0.766457
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 0.766457
PNPLA8 patatin-like phospholipase domain containing 8 0.766457
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.766457
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.766457
SART3 squamous cell carcinoma antigen recognized by T cells 3 0.766457
C19ORF43 chromosome 19 open reading frame 43 0.766457
CNOT1 CCR4-NOT transcription complex, subunit 1 0.766457
RASAL2 RAS protein activator like 2 0.766457
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 0.766457
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.766457
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.766457
RPS7 ribosomal protein S7 0.766457
RPS6 ribosomal protein S6 0.766457
DUSP1 dual specificity phosphatase 1 0.766457
DUSP2 dual specificity phosphatase 2 0.766457
TPT1 tumor protein, translationally-controlled 1 0.766457
SYNGAP1 synaptic Ras GTPase activating protein 1 0.766457
CAPN1 calpain 1, (mu/I) large subunit 0.766457
TYROBP TYRO protein tyrosine kinase binding protein 0.766457
SND1 staphylococcal nuclease and tudor domain containing 1 0.766457
RPL10A ribosomal protein L10a 0.766457
SRGN serglycin 0.766457
TPP2 tripeptidyl peptidase II 0.766457
RPS5 ribosomal protein S5 0.766457
RPS3 ribosomal protein S3 0.766457
RPS9 ribosomal protein S9 0.766457
RPS8 ribosomal protein S8 0.766457
RPL28 ribosomal protein L28 0.766457
RPL24 ribosomal protein L24 0.766457
RPL27 ribosomal protein L27 0.766457
RPL23 ribosomal protein L23 0.766457
KLRF1 killer cell lectin-like receptor subfamily F, member 1 0.766457
RUNX3 runt-related transcription factor 3 0.766457
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.766457
RPL36A ribosomal protein L36a 0.766457
EEF2 eukaryotic translation elongation factor 2 0.766457
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.766457
RPS13 ribosomal protein S13 0.766457
RPS11 ribosomal protein S11 0.766457
RPS16 ribosomal protein S16 0.766457
RPS15 ribosomal protein S15 0.766457
RPS14 ribosomal protein S14 0.766457
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.766457
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.766457
RPL41 ribosomal protein L41 0.766457
YARS tyrosyl-tRNA synthetase 0.766457
ALB albumin 0.766457
LAPTM5 lysosomal protein transmembrane 5 0.766457
SF3B3 splicing factor 3b, subunit 3, 130kDa 0.766457
TMA7 translation machinery associated 7 homolog (S. cerevisiae) 0.766457
NCL nucleolin 0.766457
CLGN calmegin 0.766457
RPS19 ribosomal protein S19 0.766457
RPS18 ribosomal protein S18 0.766457
GGACT gamma-glutamylamine cyclotransferase 0.766457
RPL14 ribosomal protein L14 0.766457
RPL17 ribosomal protein L17 0.766457
RPL11 ribosomal protein L11 0.766457
RPL19 ribosomal protein L19 0.766457
PLEKHA7 pleckstrin homology domain containing, family A member 7 0.766457
ADGRG1 adhesion G protein-coupled receptor G1 0.766457
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.766457
RPS26P6 ribosomal protein S26 pseudogene 6 0.766457
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.766457
EIF4A2 eukaryotic translation initiation factor 4A2 0.766457
IRF7 interferon regulatory factor 7 0.766457
VIM vimentin 0.766457
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.766457
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.766457
CUL3 cullin 3 0.766457
APMAP adipocyte plasma membrane associated protein 0.766457
TMSB4XP8 thymosin beta 4, X-linked pseudogene 8 0.766457
AKAP13 A kinase (PRKA) anchor protein 13 0.766457
CST7 cystatin F (leukocystatin) 0.766457
DOCK10 dedicator of cytokinesis 10 0.766457
DOCK11 dedicator of cytokinesis 11 0.766457
CKAP5 cytoskeleton associated protein 5 0.766457
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.766457
HNRNPM heterogeneous nuclear ribonucleoprotein M 0.766457
OAZ1 ornithine decarboxylase antizyme 1 0.766457
URI1 URI1, prefoldin-like chaperone 0.766457
RPL8 ribosomal protein L8 0.766457
PGK1 phosphoglycerate kinase 1 0.766457
SNX32 sorting nexin 32 0.766457
RPS23 ribosomal protein S23 0.766457
RPS21 ribosomal protein S21 0.766457
RPS28 ribosomal protein S28 0.766457
RPS29 ribosomal protein S29 0.766457
GLG1 golgi glycoprotein 1 0.766457
TMSB4X thymosin beta 4, X-linked 0.766457
WDR1 WD repeat domain 1 0.766457
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 0.766457
RPL9 ribosomal protein L9 0.766457
RPL6 ribosomal protein L6 0.766457
ESYT2 extended synaptotagmin-like protein 2 0.766457
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.766457
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.766457
FTH1 ferritin, heavy polypeptide 1 0.766457
S100A10 S100 calcium binding protein A10 0.766457
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.766457
GRTP1 growth hormone regulated TBC protein 1 0.766457
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.766457
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.766457
GLTSCR2 glioma tumor suppressor candidate region gene 2 0.766457
RPL4 ribosomal protein L4 0.766457
RPL5 ribosomal protein L5 0.766457
ACO2 aconitase 2, mitochondrial 0.766457
JAK1 Janus kinase 1 0.766457
KLF2 Kruppel-like factor 2 0.766457
EPRS glutamyl-prolyl-tRNA synthetase 0.766457
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 0.766457
NUP210 nucleoporin 210kDa 0.766457
RPS25 ribosomal protein S25 0.766457
RPS24 ribosomal protein S24 0.766457
SLK STE20-like kinase 0.766457
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 0.766457
CD247 CD247 molecule 0.766457
TRBC1 T cell receptor beta constant 1 0.766457
TRBC2 T cell receptor beta constant 2 0.766457
STIP1 stress-induced phosphoprotein 1 0.766457
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.766457
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.766457
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase 0.766457
GDI2 GDP dissociation inhibitor 2 0.766457
BTG1 B-cell translocation gene 1, anti-proliferative 0.766457
SH3KBP1 SH3-domain kinase binding protein 1 0.766457
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.766457
RPL17P9 ribosomal protein L17 pseudogene 9 0.766457
RPL18A ribosomal protein L18a 0.766457
KRT37 keratin 37, type I 0.766457
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.766457
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.766457
UBA6 ubiquitin-like modifier activating enzyme 6 0.766457
UBA1 ubiquitin-like modifier activating enzyme 1 0.766457
HOPX HOP homeobox 0.766457
RPL37A ribosomal protein L37a 0.766457
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.766457
EFHD2 EF-hand domain family, member D2 0.766457
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.766457
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 0.766457
HCLS1 hematopoietic cell-specific Lyn substrate 1 0.766457
RPS26 ribosomal protein S26 0.766457
ANKRD20A1 ankyrin repeat domain 20 family, member A1 0.766457
ANKRD20A3 ankyrin repeat domain 20 family, member A3 0.766457
PLAC8 placenta-specific 8 0.766457
NR6A1 nuclear receptor subfamily 6, group A, member 1 0.766457
FERMT3 fermitin family member 3 0.766457
DCTN1 dynactin 1 0.766457
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.766457
ITGB7 integrin, beta 7 0.766457
FGB fibrinogen beta chain 0.766457
ZNF33A zinc finger protein 33A 0.766457
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.766457
S100A4 S100 calcium binding protein A4 0.766457
EEF1B2 eukaryotic translation elongation factor 1 beta 2 0.766457
XPO1 exportin 1 0.766457
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 0.766457
RHOA ras homolog family member A 0.766457
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.766457
C1ORF35 chromosome 1 open reading frame 35 0.766457
RPL37 ribosomal protein L37 0.766457
MYO9B myosin IXB 0.766457
STAG1 stromal antigen 1 0.766457
SLFN5 schlafen family member 5 0.766457
RPL35A ribosomal protein L35a 0.766457
PFN1 profilin 1 0.766457
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.766457
GALNT9 polypeptide N-acetylgalactosaminyltransferase 9 0.766457
ZFP36 ZFP36 ring finger protein 0.766457
COPB1 coatomer protein complex, subunit beta 1 0.766457
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 0.766457
NEFH neurofilament, heavy polypeptide 0.766457
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 0.766457
P4HB prolyl 4-hydroxylase, beta polypeptide 0.766457
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.766457
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.766457
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.766457
IL2RB interleukin 2 receptor, beta 0.766457
U2SURP U2 snRNP-associated SURP domain containing 0.766457
RECQL RecQ helicase-like 0.766457
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.766457
EIF1 eukaryotic translation initiation factor 1 0.766457
MYO1D myosin ID 0.766457
MYO1G myosin IG 0.766457
NBEAL2 neurobeachin-like 2 0.766457
SPON2 spondin 2, extracellular matrix protein 0.766457
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.766457
ABHD17AP1 abhydrolase domain containing 17A pseudogene 1 0.766457
CAND1 cullin-associated and neddylation-dissociated 1 0.766457
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.766457
EIF3L eukaryotic translation initiation factor 3, subunit L 0.766457
UTRN utrophin 0.766457
PYGB phosphorylase, glycogen; brain 0.766457
ANXA2 annexin A2 0.766457
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.766457
PRF1 perforin 1 (pore forming protein) 0.766457
LMNB1 lamin B1 0.766457
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 0.766457
KRT18 keratin 18, type I 0.766457
ABHD17A abhydrolase domain containing 17A 0.766457
CYBA cytochrome b-245, alpha polypeptide 0.766457
HMHA1 histocompatibility (minor) HA-1 0.766457
RAP1B RAP1B, member of RAS oncogene family 0.766457
H3F3A H3 histone, family 3A 0.766457
B2M beta-2-microglobulin 0.766457
PSAP prosaposin 0.766457
TXNIP thioredoxin interacting protein 0.766457
CLIC1 chloride intracellular channel 1 0.766457
AP2A1 adaptor-related protein complex 2, alpha 1 subunit 0.766457
ARHGAP22 Rho GTPase activating protein 22 0.766457
H3F3C H3 histone, family 3C 0.766457
H3F3B H3 histone, family 3B (H3.3B) 0.766457
ACLY ATP citrate lyase 0.766457
PRPF6 pre-mRNA processing factor 6 0.766457
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.766457
LONP1 lon peptidase 1, mitochondrial 0.766457
TKT transketolase 0.766457
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.766457
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast) 0.766457
EIF3F eukaryotic translation initiation factor 3, subunit F 0.766457
CHCHD2P9 coiled-coil-helix-coiled-coil-helix domain containing 2 pseudogene 9 0.766457
ANXA1 annexin A1 0.766457
UBC ubiquitin C 0.766457
UBB ubiquitin B 0.766457
TMSB10 thymosin beta 10 0.766457
TRIM28 tripartite motif containing 28 0.766457
TRIM29 tripartite motif containing 29 0.766457
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.766457
CANX calnexin 0.766457
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.766457
HLA-E major histocompatibility complex, class I, E 0.766457
IPO5 importin 5 0.766457
NUP93 nucleoporin 93kDa 0.766457