lamellar body Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome. (Gene Ontology, GO_0042599)
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Genes

166 proteins co-occuring with the lamellar body cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 2.35367
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 2.14132
SFTPB surfactant protein B 2.06923
SFTPC surfactant protein C 2.00335
PROS2P protein S (beta) pseudogene 1.79574
FLG filaggrin 1.75852
LOR loricrin 1.48249
IVL involucrin 1.42711
NIPAL4 NIPA-like domain containing 4 1.25338
TMEM79 transmembrane protein 79 1.22932
NKX2-1 NK2 homeobox 1 1.17106
SPINK5 serine peptidase inhibitor, Kazal type 5 1.15416
SFTPD surfactant protein D 1.1342
GBA glucosidase, beta, acid 1.13012
ALOX12B arachidonate 12-lipoxygenase, 12R type 1.12501
ANXA7 annexin A7 0.994652
CDSN corneodesmosin 0.970814
TGM1 transglutaminase 1 0.952573
KRTDAP keratinocyte differentiation-associated protein 0.923259
ACPP acid phosphatase, prostate 0.890245
ALOXE3 arachidonate lipoxygenase 3 0.881477
RAB38 RAB38, member RAS oncogene family 0.823582
CASP14 caspase 14, apoptosis-related cysteine peptidase 0.814864
SFTA2 surfactant associated 2 0.79148
KLK7 kallikrein-related peptidase 7 0.790564
UGCG UDP-glucose ceramide glucosyltransferase 0.785529
DEFB4A defensin, beta 4A 0.75317
FGF7 fibroblast growth factor 7 0.752263
ARMC9 armadillo repeat containing 9 0.752263
TMEM45A transmembrane protein 45A 0.742769
FOXA2 forkhead box A2 0.736464
ECI1 enoyl-CoA delta isomerase 1 0.731973
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.729284
CLIP2 CAP-GLY domain containing linker protein 2 0.727047
A2ML1 alpha-2-macroglobulin-like 1 0.713238
LPCAT3 lysophosphatidylcholine acyltransferase 3 0.699543
KLK5 kallikrein-related peptidase 5 0.687264
AQP5 aquaporin 5 0.681155
HPS1 Hermansky-Pudlak syndrome 1 0.668559
ANXA2 annexin A2 0.65905
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.655172
CAMP cathelicidin antimicrobial peptide 0.65388
CPM carboxypeptidase M 0.647003
KLK6 kallikrein-related peptidase 6 0.640145
DEFB103B defensin, beta 103B 0.638434
FLG2 filaggrin family member 2 0.638434
CTSH cathepsin H 0.634586
PRDX6 peroxiredoxin 6 0.614589
CRTAC1 cartilage acidic protein 1 0.608241
VPS33B vacuolar protein sorting 33 homolog B (yeast) 0.579669
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.576747
SH3GLB2 SH3-domain GRB2-like endophilin B2 0.563017
DSG1 desmoglein 1 0.544
KRT80 keratin 80, type II 0.539472
LYZ lysozyme 0.53906
ACSM2A acyl-CoA synthetase medium-chain family member 2A 0.536594
CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22 0.534951
SC5D sterol-C5-desaturase 0.530847
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.530028
DSC1 desmocollin 1 0.527569
CTSV cathepsin V 0.517756
CHKA choline kinase alpha 0.515308
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 0.510826
LAMP3 lysosomal-associated membrane protein 3 0.504318
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.501881
GPR89B G protein-coupled receptor 89B 0.493775
GPR89A G protein-coupled receptor 89A 0.493775
ELOVL3 ELOVL fatty acid elongase 3 0.490135
HRNR hornerin 0.490135
PLA2G1B phospholipase A2, group IB (pancreas) 0.490135
LRRC38 leucine rich repeat containing 38 0.476429
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 0.472011
ALB albumin 0.470406
STS steroid sulfatase (microsomal), isozyme S 0.461599
PPARA peroxisome proliferator-activated receptor alpha 0.455214
ALPPL2 alkaline phosphatase, placental-like 2 0.452427
ALPL alkaline phosphatase, liver/bone/kidney 0.452029
ALPP alkaline phosphatase, placental 0.451631
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 0.436565
PCTP phosphatidylcholine transfer protein 0.436565
MAGEE1 melanoma antigen family E1 0.415337
RPTN repetin 0.40714
AATF apoptosis antagonizing transcription factor 0.381199
FASN fatty acid synthase 0.372366
ABHD5 abhydrolase domain containing 5 0.368536
CTSD cathepsin D 0.367771
IL1A interleukin 1, alpha 0.364713
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.361659
GLG1 golgi glycoprotein 1 0.360896
SOCS5 suppressor of cytokine signaling 5 0.357086
RAB4B RAB4B, member RAS oncogene family 0.355183
DEFB103A defensin, beta 103A 0.348346
SNAP23 synaptosomal-associated protein, 23kDa 0.346829
STX2 syntaxin 2 0.343042
INS insulin 0.339639
SPRR3 small proline-rich protein 3 0.338884
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.332095
NSF N-ethylmaleimide-sensitive factor 0.326829
MFSD8 major facilitator superfamily domain containing 8 0.324201
PGC progastricsin (pepsinogen C) 0.320826
BPIFA1 BPI fold containing family A, member 1 0.318579
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.318205
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.314465
FA2H fatty acid 2-hydroxylase 0.311478
DAND5 DAN domain family member 5, BMP antagonist 0.310732
ADSL adenylosuccinate lyase 0.306632
ANXA8 annexin A8 0.303655
GPR162 G protein-coupled receptor 162 0.301797
LAMP1 lysosomal-associated membrane protein 1 0.300311
CST6 cystatin E/M 0.29586
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 0.293267
CHPT1 choline phosphotransferase 1 0.291047
CLIP1 CAP-GLY domain containing linker protein 1 0.287721
IL1RL1 interleukin 1 receptor-like 1 0.285138
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.283295
PLIN2 perilipin 2 0.280716
PDPN podoplanin 0.279245
FTL ferritin, light polypeptide 0.278509
FTH1 ferritin, heavy polypeptide 1 0.276671
PZP pregnancy-zone protein 0.275936
DSC3 desmocollin 3 0.274468
SPAG11A sperm associated antigen 11A 0.268237
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.268237
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 0.26239
PLBD2 phospholipase B domain containing 2 0.255107
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 0.253291
HIF3A hypoxia inducible factor 3, alpha subunit 0.252927
PCNA proliferating cell nuclear antigen 0.249664
SZRD1 SUZ RNA binding domain containing 1 0.247854
PPARD peroxisome proliferator-activated receptor delta 0.24713
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9 0.244962
SPAG11B sperm associated antigen 11B 0.243879
BTG3 BTG family, member 3 0.241716
GNPAT glyceronephosphate O-acyltransferase 0.241716
CEPT1 choline/ethanolamine phosphotransferase 1 0.238119
TGFB1 transforming growth factor, beta 1 0.232744
TCHH trichohyalin 0.231315
HPS4 Hermansky-Pudlak syndrome 4 0.226686
KRT16 keratin 16, type I 0.22173
PLIN4 perilipin 4 0.21681
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 0.215761
CTSC cathepsin C 0.213322
NAPSA napsin A aspartic peptidase 0.204718
ELOVL4 ELOVL fatty acid elongase 4 0.199993
EMP1 epithelial membrane protein 1 0.19733
PLA2G5 phospholipase A2, group V 0.196669
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 0.195353
CHAT choline O-acetyltransferase 0.190175
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.18796
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 0.184241
CLDN18 claudin 18 0.183935
LRRK2 leucine-rich repeat kinase 2 0.179459
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.176587
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.174911
NPC1 Niemann-Pick disease, type C1 0.174087
ANXA4 annexin A4 0.173003
EPCAM epithelial cell adhesion molecule 0.172468
SRCIN1 SRC kinase signaling inhibitor 1 0.170629
DUOX1 dual oxidase 1 0.169099
PODXL podocalyxin-like 0.167856
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 0.1632
DUOXA1 dual oxidase maturation factor 1 0.16298
CAV1 caveolin 1, caveolae protein, 22kDa 0.16233
IFITM2 interferon induced transmembrane protein 2 0.161068
CD44 CD44 molecule (Indian blood group) 0.159462
VEGFA vascular endothelial growth factor A 0.138299