lagging strand elongation Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The synthesis of DNA from a template strand in a net 3' to 5' direction. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork. (Gene Ontology, GO_0006273)
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3 genes participating in the lagging strand elongation biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
LIG3 ligase III, DNA, ATP-dependent
LIG4 ligase IV, DNA, ATP-dependent
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit