kinetochore Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. (Gene Ontology, GO_0000776)
Similar Terms
Downloads & Tools

Genes

288 proteins co-occuring with the kinetochore cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 2.67884
AURKB aurora kinase B 2.63131
CENPE centromere protein E, 312kDa 2.59266
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 2.51958
CENPC centromere protein C 2.40092
NDC80 NDC80 kinetochore complex component 2.2869
BUB3 BUB3 mitotic checkpoint protein 2.10711
CDC20 cell division cycle 20 2.06923
ZW10 zw10 kinetochore protein 2.05612
CENPF centromere protein F, 350/400kDa 1.99119
CENPH centromere protein H 1.95162
CASC5 cancer susceptibility candidate 5 1.93692
APITD1 apoptosis-inducing, TAF9-like domain 1 1.86486
NUF2 NUF2, NDC80 kinetochore complex component 1.83543
INCENP inner centromere protein antigens 135/155kDa 1.82321
CENPA centromere protein A 1.77665
CENPT centromere protein T 1.74956
CENPB centromere protein B, 80kDa 1.74956
PLK1 polo-like kinase 1 1.73877
ZWINT ZW10 interacting kinetochore protein 1.71684
ZWILCH zwilch kinetochore protein 1.68665
MIS12 MIS12 kinetochore complex component 1.65152
SPC24 SPC24, NDC80 kinetochore complex component 1.55537
H3F3A H3 histone, family 3A 1.54461
H3F3B H3 histone, family 3B (H3.3B) 1.54461
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 1.54461
H3F3C H3 histone, family 3C 1.47627
SPC25 SPC25, NDC80 kinetochore complex component 1.45703
KIF2C kinesin family member 2C 1.44403
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 1.44121
SKA1 spindle and kinetochore associated complex subunit 1 1.43839
SGOL1 shugoshin-like 1 (S. pombe) 1.4125
DCTN1 dynactin 1 1.4041
CENPU centromere protein U 1.38461
CENPW centromere protein W 1.37243
SKA3 spindle and kinetochore associated complex subunit 3 1.32492
BIRC5 baculoviral IAP repeat containing 5 1.32275
HJURP Holliday junction recognition protein 1.31735
CDK1 cyclin-dependent kinase 1 1.26445
ERCC6L excision repair cross-complementation group 6-like 1.19211
SGOL2 shugoshin-like 2 (S. pombe) 1.18492
CDCA8 cell division cycle associated 8 1.18132
PTTG1 pituitary tumor-transforming 1 1.17876
CKAP5 cytoskeleton associated protein 5 1.17465
CENPN centromere protein N 1.17106
KIF18A kinesin family member 18A 1.16901
CENPL centromere protein L 1.16184
CENPQ centromere protein Q 1.15723
KIF11 kinesin family member 11 1.13012
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 1.13012
SKA2 spindle and kinetochore associated complex subunit 2 1.09289
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 1.05136
KIF2B kinesin family member 2B 1.04431
KIF2A kinesin heavy chain member 2A 1.03679
SPDL1 spindle apparatus coiled-coil protein 1 1.01933
BCAS2 breast carcinoma amplified sequence 2 1.01486
RAD21 RAD21 homolog (S. pombe) 1.01387
KIF4A kinesin family member 4A 0.984393
CLASP1 cytoplasmic linker associated protein 1 0.976135
DCTN2 dynactin 2 (p50) 0.97323
CLIP1 CAP-GLY domain containing linker protein 1 0.95831
MPEG1 macrophage expressed 1 0.950665
STRA13 stimulated by retinoic acid 13 0.934544
TPX2 TPX2, microtubule-associated 0.924197
DSN1 DSN1, MIS12 kinetochore complex component 0.919514
TACC3 transforming, acidic coiled-coil containing protein 3 0.916243
RANGAP1 Ran GTPase activating protein 1 0.872266
KNTC1 kinetochore associated 1 0.868586
RANBP2 RAN binding protein 2 0.862149
NSL1 NSL1, MIS12 kinetochore complex component 0.86077
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) 0.860311
HAUS6 HAUS augmin-like complex, subunit 6 0.852502
CCNB1 cyclin B1 0.841023
SKP1 S-phase kinase-associated protein 1 0.831384
MIS18BP1 MIS18 binding protein 1 0.8089
AHCTF1 AT hook containing transcription factor 1 0.789191
MAD2L1P1 MAD2 mitotic arrest deficient-like 1 (yeast) pseudogene 1 0.782784
NUMA1 nuclear mitotic apparatus protein 1 0.776841
SPAG5 sperm associated antigen 5 0.775471
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.772732
AURKC aurora kinase C 0.750904
DIAPH2 diaphanous-related formin 2 0.742318
ZNF207 zinc finger protein 207 0.741416
TRIM17 tripartite motif containing 17 0.727941
KLHL22 kelch-like family member 22 0.691202
BOD1 biorientation of chromosomes in cell division 1 0.684644
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.683771
KIF15 kinesin family member 15 0.681591
TRIP13 thyroid hormone receptor interactor 13 0.680284
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.675065
NUP107 nucleoporin 107kDa 0.6638
CLASP2 cytoplasmic linker associated protein 2 0.65905
TUBA1A tubulin, alpha 1a 0.646145
REC8 REC8 meiotic recombination protein 0.641001
CIB3 calcium and integrin binding family member 3 0.638861
AURKA aurora kinase A 0.636723
NEK2 NIMA-related kinase 2 0.635868
RGPD3 RANBP2-like and GRIP domain containing 3 0.630745
CDC14A cell division cycle 14A 0.629892
PLK2 polo-like kinase 2 0.609932
HIST2H2AC histone cluster 2, H2ac 0.577999
HIST2H2AA4 histone cluster 2, H2aa4 0.577581
HIST2H2AA3 histone cluster 2, H2aa3 0.577581
NIPBL Nipped-B homolog (Drosophila) 0.569248
CHAMP1 chromosome alignment maintaining phosphoprotein 1 0.563017
RAN RAN, member RAS oncogene family 0.558871
CNTLN centlein, centrosomal protein 0.558457
CBX5 chromobox homolog 5 0.546472
FAM98A family with sequence similarity 98, member A 0.536183
CCDC93 coiled-coil domain containing 93 0.536183
CCDC22 coiled-coil domain containing 22 0.536183
SUMO1 small ubiquitin-like modifier 1 0.535361
SEH1L SEH1-like (S. cerevisiae) 0.534951
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 0.532898
PPP1R7 protein phosphatase 1, regulatory subunit 7 0.527979
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene) 0.52716
SMC2 structural maintenance of chromosomes 2 0.524704
CEP126 centrosomal protein 126kDa 0.521023
TTK TTK protein kinase 0.518981
DYNLT3 dynein, light chain, Tctex-type 3 0.505131
ZNF397 zinc finger protein 397 0.501881
NUDCD2 NudC domain containing 2 0.500258
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.49661
NCAPG2 non-SMC condensin II complex, subunit G2 0.489731
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.488923
H2AFY2 H2A histone family, member Y2 0.483676
NUP37 nucleoporin 37kDa 0.478843
SENP6 SUMO1/sentrin specific peptidase 6 0.458404
CDC27 cell division cycle 27 0.454816
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 0.453621
KIF22 kinesin family member 22 0.449245
MAP4 microtubule-associated protein 4 0.444878
PCSK7 proprotein convertase subtilisin/kexin type 7 0.444085
TP53 tumor protein p53 0.443689
SMC3 structural maintenance of chromosomes 3 0.4425
TPR translocated promoter region, nuclear basket protein 0.43617
HIST1H2AM histone cluster 1, H2am 0.431041
HIST1H2AJ histone cluster 1, H2aj 0.431041
HIST1H2AH histone cluster 1, H2ah 0.431041
H2AFJ H2A histone family, member J 0.431041
HIST1H2AD histone cluster 1, H2ad 0.431041
HIST1H2AG histone cluster 1, H2ag 0.429465
APC adenomatous polyposis coli 0.428678
APTX aprataxin 0.428416
HIST1H2AB histone cluster 1, H2ab 0.427104
HIST1H2AE histone cluster 1, H2ae 0.427104
H2AFV H2A histone family, member V 0.427104
H2AFB1 H2A histone family, member B1 0.42396
H2AFB2 H2A histone family, member B2 0.420428
H2AFY H2A histone family, member Y 0.416902
PARK2 parkin RBR E3 ubiquitin protein ligase 0.414946
DDX11L8 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 like 8 0.410649
CHEK1 checkpoint kinase 1 0.409089
GTSF1 gametocyte specific factor 1 0.401693
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.397035
NUP43 nucleoporin 43kDa 0.393549
CEP72 centrosomal protein 72kDa 0.390841
CEP57 centrosomal protein 57kDa 0.390068
SUMO2 small ubiquitin-like modifier 2 0.388137
PCNT pericentrin 0.385051
DBF4 DBF4 zinc finger 0.377738
SPATC1 spermatogenesis and centriole associated 1 0.373516
CETN1 centrin, EF-hand protein, 1 0.37045
NUP133 nucleoporin 133kDa 0.368919
CDC5L cell division cycle 5-like 0.367771
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.366241
TRIM36 tripartite motif containing 36 0.364713
CLUAP1 clusterin associated protein 1 0.36204
MAP7D3 MAP7 domain containing 3 0.35899
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.357086
NUDCD3 NudC domain containing 3 0.351382
CSNK1D casein kinase 1, delta 0.348725
NCAPG non-SMC condensin I complex, subunit G 0.348725
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.342664
RGPD1 RANBP2-like and GRIP domain containing 1 0.337373
KLHL13 kelch-like family member 13 0.33511
KLHL9 kelch-like family member 9 0.330213
KIF23 kinesin family member 23 0.328332
SYCP3 synaptonemal complex protein 3 0.326453
MCRS1 microspherule protein 1 0.324951
XPO1 exportin 1 0.320077
ATM ATM serine/threonine kinase 0.316708
DNAH12 dynein, axonemal, heavy chain 12 0.313344
DNAH14 dynein, axonemal, heavy chain 14 0.313344
MAP2 microtubule-associated protein 2 0.307377
SUMO3 small ubiquitin-like modifier 3 0.304771
TEX14 testis expressed 14 0.302912
FAM83D family with sequence similarity 83, member D 0.300311
CDC7 cell division cycle 7 0.298826
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.296972
MAPT microtubule-associated protein tau 0.295489
DNAH5 dynein, axonemal, heavy chain 5 0.287721
SMC6 structural maintenance of chromosomes 6 0.27998
HAUS8 HAUS augmin-like complex, subunit 8 0.279612
CETN2 centrin, EF-hand protein, 2 0.279245
ANAPC13 anaphase promoting complex subunit 13 0.277038
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 0.268969
WAPAL wings apart-like homolog (Drosophila) 0.268603
C14ORF166 chromosome 14 open reading frame 166 0.266774
STX18 syntaxin 18 0.266774
KIF18B kinesin family member 18B 0.264946
MISP mitotic spindle positioning 0.264215
NUP98 nucleoporin 98kDa 0.26385
SMC1A structural maintenance of chromosomes 1A 0.26312
CDC16 cell division cycle 16 0.26239
PEBP1 phosphatidylethanolamine binding protein 1 0.259473
NUP188 nucleoporin 188kDa 0.253291
RABGAP1 RAB GTPase activating protein 1 0.250751
H2AFX H2A histone family, member X 0.249302
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.248216
NIN ninein (GSK3B interacting protein) 0.247854
AJUBA ajuba LIM protein 0.243879
TUBGCP3 tubulin, gamma complex associated protein 3 0.241356
GPR162 G protein-coupled receptor 162 0.239197
UBE2G1 ubiquitin-conjugating enzyme E2G 1 0.235249
STAG3 stromal antigen 3 0.234533
USP44 ubiquitin specific peptidase 44 0.233459
RBMY1F RNA binding motif protein, Y-linked, family 1, member F 0.232744
DNAH9 dynein, axonemal, heavy chain 9 0.232744
CUL3 cullin 3 0.228464
CDC23 cell division cycle 23 0.227041
GPC2 glypican 2 0.22279
MCC mutated in colorectal cancers 0.222083
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.219265
PLK3 polo-like kinase 3 0.215761
RBMXL1 RNA binding motif protein, X-linked-like 1 0.212627
HIST1H4F histone cluster 1, H4f 0.209858
HIST1H4J histone cluster 1, H4j 0.209858
HIST1H4E histone cluster 1, H4e 0.209858
HIST1H4I histone cluster 1, H4i 0.209858
HIST1H4A histone cluster 1, H4a 0.209858
HIST1H4D histone cluster 1, H4d 0.209858
HIST1H4H histone cluster 1, H4h 0.209858
HIST1H4K histone cluster 1, H4k 0.209858
HIST2H4B histone cluster 2, H4b 0.209858
HIST2H4A histone cluster 2, H4a 0.209858
HIST1H4B histone cluster 1, H4b 0.209858
HIST1H4C histone cluster 1, H4c 0.209858
HIST4H4 histone cluster 4, H4 0.209513
HIST1H4L histone cluster 1, H4l 0.209513
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.208137
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.203361
NUDC nudC nuclear distribution protein 0.201672
SENP1 SUMO1/sentrin specific peptidase 1 0.201672
PBRM1 polybromo 1 0.201335
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.200328
ENSA endosulfine alpha 0.199993
BRCA1 breast cancer 1, early onset 0.199659
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.198325
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.194045
FIGN fidgetin 0.191456
RAE1 ribonucleic acid export 1 0.189539
RMDN3 regulator of microtubule dynamics 3 0.189539
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.188274
METTL13 methyltransferase like 13 0.188274
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.187333
RBMY1J RNA binding motif protein, Y-linked, family 1, member J 0.18702
SEPT5 septin 5 0.186397
MAPK6 mitogen-activated protein kinase 6 0.184547
PRC1 protein regulator of cytokinesis 1 0.183025
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.183025
CECR2 cat eye syndrome chromosome region, candidate 2 0.182723
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.180634
KIZ kizuna centrosomal protein 0.180339
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.179167
BEGAIN brain-enriched guanylate kinase-associated 0.176587
STAC SH3 and cysteine rich domain 0.174635
IK IK cytokine, down-regulator of HLA II 0.174361
IFT81 intraflagellar transport 81 0.171673
CDC34 cell division cycle 34 0.17141
RBMX RNA binding motif protein, X-linked 0.17141
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.168598
OSBPL8 oxysterol binding protein-like 8 0.166884
PFKL phosphofructokinase, liver 0.165932
UBE2G2 ubiquitin-conjugating enzyme E2G 2 0.165697
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 0.165231
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.161484
IL20RB interleukin 20 receptor beta 0.160053
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.158882
NDEL1 nudE neurodevelopment protein 1-like 1 0.158692
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae) 0.158315
NCAPD2 non-SMC condensin I complex, subunit D2 0.157039
TOP1 topoisomerase (DNA) I 0.156863
RACGAP1 Rac GTPase activating protein 1 0.156513
HIPK3 homeodomain interacting protein kinase 3 0.141722
MAML1 mastermind-like 1 (Drosophila) 0.140588
LARGE like-glycosyltransferase 0.140012
PLK4 polo-like kinase 4 0.132448