killer Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

308 genes co-occuring with the biological term killer in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10
ADGRG1 adhesion G protein-coupled receptor G1
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRB2 adrenoceptor beta 2, surface
AGA aspartylglucosaminidase
B2M beta-2-microglobulin
B3GAT1 beta-1,3-glucuronyltransferase 1
BAK1 BCL2-antagonist/killer 1
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BECN1 beclin 1, autophagy related
BIK BCL2-interacting killer (apoptosis-inducing)
BIRC7 baculoviral IAP repeat containing 7
BST2 bone marrow stromal cell antigen 2
CALR calreticulin
CAPN3 calpain 3, (p94)
CCL26 chemokine (C-C motif) ligand 26
CCL3 chemokine (C-C motif) ligand 3
CCL4 chemokine (C-C motif) ligand 4
CCL5 chemokine (C-C motif) ligand 5
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR4 chemokine (C-C motif) receptor 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CD160 CD160 molecule
CD1C CD1c molecule
CD1D CD1d molecule
CD2 CD2 molecule
CD200R1 CD200 receptor 1
CD226 CD226 molecule
CD244 CD244 molecule, natural killer cell receptor 2B4
CD247 CD247 molecule
CD27 CD27 molecule
CD274 CD274 molecule
CD276 CD276 molecule
CD300A CD300a molecule
CD300C CD300c molecule
CD33 CD33 molecule
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD48 CD48 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD58 CD58 molecule
CD59 CD59 molecule, complement regulatory protein
CD69 CD69 molecule
CD7 CD7 molecule
CD86 CD86 molecule
CD96 CD96 molecule
CD99 CD99 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CGA glycoprotein hormones, alpha polypeptide
CLEC2D C-type lectin domain family 2, member D
CNTFR ciliary neurotrophic factor receptor
CRH corticotropin releasing hormone
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR5 chemokine (C-X-C motif) receptor 5
CXCR6 chemokine (C-X-C motif) receptor 6
CYR61 cysteine-rich, angiogenic inducer, 61
DEK DEK proto-oncogene
DOCK8 dedicator of cytokinesis 8
EGR1 early growth response 1
EPAS1 endothelial PAS domain protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ESRRB estrogen-related receptor beta
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCRL6 Fc receptor-like 6
FLT3LG fms-related tyrosine kinase 3 ligand
FOSL2 FOS-like antigen 2
FOXA1 forkhead box A1
FOXP3 forkhead box P3
FPR1 formyl peptide receptor 1
FPR2 formyl peptide receptor 2
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GATA2 GATA binding protein 2
GCG glucagon
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GLP1R glucagon-like peptide 1 receptor
GMDS GDP-mannose 4,6-dehydratase
GNLY granulysin
GP6 glycoprotein VI (platelet)
GRP gastrin-releasing peptide
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
GZMK granzyme K (granzyme 3; tryptase II)
GZMM granzyme M (lymphocyte met-ase 1)
HAVCR2 hepatitis A virus cellular receptor 2
HCST hematopoietic cell signal transducer
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-E major histocompatibility complex, class I, E
HLA-G major histocompatibility complex, class I, G
HSF1 heat shock transcription factor 1
HSPA1A heat shock 70kDa protein 1A
HSPA4 heat shock 70kDa protein 4
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
ICAM1 intercellular adhesion molecule 1
ICOS inducible T-cell co-stimulator
IDO1 indoleamine 2,3-dioxygenase 1
IFITM1 interferon induced transmembrane protein 1
IFN1@ interferon, type 1, cluster
IFNA1 interferon, alpha 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNL3 interferon, lambda 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL12RB1 interleukin 12 receptor, beta 1
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL17A interleukin 17A
IL17D interleukin 17D
IL17F interleukin 17F
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IL18RAP interleukin 18 receptor accessory protein
IL2 interleukin 2
IL21 interleukin 21
IL22 interleukin 22
IL27 interleukin 27
IL27RA interleukin 27 receptor, alpha
IL2RG interleukin 2 receptor, gamma
IL32 interleukin 32
IL4 interleukin 4
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
IL7 interleukin 7
ITGA1 integrin, alpha 1
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR2DS3 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KISS1 KiSS-1 metastasis-suppressor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KLRC2 killer cell lectin-like receptor subfamily C, member 2
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LAT linker for activation of T cells
LAT2 linker for activation of T cells family, member 2
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LEF1 lymphoid enhancer-binding factor 1
LEP leptin
LEPR leptin receptor
LGALS9 lectin, galactoside-binding, soluble, 9
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LPL lipoprotein lipase
LST1 leukocyte specific transcript 1
LTA lymphotoxin alpha
LYST lysosomal trafficking regulator
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MCM4 minichromosome maintenance complex component 4
MDK midkine (neurite growth-promoting factor 2)
MICA MHC class I polypeptide-related sequence A
MICB MHC class I polypeptide-related sequence B
MIR125B1 microRNA 125b-1
MIR125B2 microRNA 125b-2
MIR17 microRNA 17
MIR181A2 microRNA 181a-2
MIR183 microRNA 183
MIR20A microRNA 20a
MIR30E microRNA 30e
MIR378A microRNA 378a
MKI67 marker of proliferation Ki-67
MKNK1 MAP kinase interacting serine/threonine kinase 1
MME membrane metallo-endopeptidase
MMP2 matrix metallopeptidase 2
MRC1 mannose receptor, C type 1
MUC1 mucin 1, cell surface associated
MUC16 mucin 16, cell surface associated
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NCAM1 neural cell adhesion molecule 1
NCR1 natural cytotoxicity triggering receptor 1
NCR2 natural cytotoxicity triggering receptor 2
NCR3 natural cytotoxicity triggering receptor 3
NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1
NCS1 neuronal calcium sensor 1
NT5C1A 5'-nucleotidase, cytosolic IA
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PDCD2 programmed cell death 2
PDCD2L programmed cell death 2-like
PF4 platelet factor 4
PIBF1 progesterone immunomodulatory binding factor 1
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLAU plasminogen activator, urokinase
PLCG1 phospholipase C, gamma 1
PPARG peroxisome proliferator-activated receptor gamma
PRDM1 PR domain containing 1, with ZNF domain
PRF1 perforin 1 (pore forming protein)
PRKCD protein kinase C, delta
PRKCZ protein kinase C, zeta
PROCR protein C receptor, endothelial
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PVR poliovirus receptor
RAE1 ribonucleic acid export 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RNF216 ring finger protein 216
RUNX3 runt-related transcription factor 3
SDC1 syndecan 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SFTPA1 surfactant protein A1
SH2D1A SH2 domain containing 1A
SH2D1B SH2 domain containing 1B
SH3BP2 SH3-domain binding protein 2
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLAMF1 signaling lymphocytic activation molecule family member 1
SLAMF6 SLAM family member 6
SLAMF7 SLAM family member 7
SMAD3 SMAD family member 3
SOCS3 suppressor of cytokine signaling 3
SP1 Sp1 transcription factor
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STMN1 stathmin 1
STX11 syntaxin 11
STXBP2 syntaxin binding protein 2
TBX21 T-box 21
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TERF2 telomeric repeat binding factor 2
TGFB1 transforming growth factor, beta 1
TIMP2 TIMP metallopeptidase inhibitor 2
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNR tenascin R
TOX thymocyte selection-associated high mobility group box
TP53 tumor protein p53
TRA T cell receptor alpha locus
TRAV24 T cell receptor alpha variable 24
TRB T cell receptor beta locus
TRG T cell receptor gamma locus
TXNIP thioredoxin interacting protein
TXNRD1 thioredoxin reductase 1
TYROBP TYRO protein tyrosine kinase binding protein
ULBP1 UL16 binding protein 1
ULBP2 UL16 binding protein 2
ULBP3 UL16 binding protein 3
UNC13D unc-13 homolog D (C. elegans)
VEGFC vascular endothelial growth factor C
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIP vasoactive intestinal peptide
VTCN1 V-set domain containing T cell activation inhibitor 1
WAS Wiskott-Aldrich syndrome
WIPF1 WAS/WASL interacting protein family, member 1
ZBTB16 zinc finger and BTB domain containing 16