ketone body biosynthetic process Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA. (Gene Ontology, GO_0046951)
External Link
Similar Terms
Downloads & Tools


6 genes participating in the ketone body biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ACAT1 acetyl-CoA acetyltransferase 1
BDH1 3-hydroxybutyrate dehydrogenase, type 1
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5