kawain-7369 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the kawain-7369 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRL1 adhesion G protein-coupled receptor L1
ANGPT4 angiopoietin 4
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ASTN2 astrotactin 2
ATAD5 ATPase family, AAA domain containing 5
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
BRCA1 breast cancer 1, early onset
C1ORF21 chromosome 1 open reading frame 21
C9ORF40 chromosome 9 open reading frame 40
CASP1 caspase 1, apoptosis-related cysteine peptidase
CLDN17 claudin 17
CREB3L1 cAMP responsive element binding protein 3-like 1
DCTN1 dynactin 1
DENND2D DENN/MADD domain containing 2D
DLX2 distal-less homeobox 2
DOCK5 dedicator of cytokinesis 5
DOK4 docking protein 4
EED embryonic ectoderm development
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EML3 echinoderm microtubule associated protein like 3
ERAP1 endoplasmic reticulum aminopeptidase 1
ESRRG estrogen-related receptor gamma
ETV1 ets variant 1
FAM120C family with sequence similarity 120C
FBXO21 F-box protein 21
FGFR1 fibroblast growth factor receptor 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GCGR glucagon receptor
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GPATCH2L G patch domain containing 2-like
GPR161 G protein-coupled receptor 161
HOXC4 homeobox C4
IFI44 interferon-induced protein 44
IL17RA interleukin 17 receptor A
KCTD14 potassium channel tetramerization domain containing 14
KIAA0391 KIAA0391
KIAA1644 KIAA1644
KLHL29 kelch-like family member 29
KLHL4 kelch-like family member 4
MDFIC MyoD family inhibitor domain containing
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MMP9 matrix metallopeptidase 9
MRPL57 mitochondrial ribosomal protein L57
NAAA N-acylethanolamine acid amidase
NDP Norrie disease (pseudoglioma)
NPPB natriuretic peptide B
OASL 2'-5'-oligoadenylate synthetase-like
OLFML2B olfactomedin-like 2B
ORC5 origin recognition complex, subunit 5
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PAX2 paired box 2
PCDHGB5 protocadherin gamma subfamily B, 5
PDGFA platelet-derived growth factor alpha polypeptide
PDLIM5 PDZ and LIM domain 5
PGLYRP4 peptidoglycan recognition protein 4
PGPEP1 pyroglutamyl-peptidase I
PLA2G15 phospholipase A2, group XV
PLXNA3 plexin A3
PMP2 peripheral myelin protein 2
PTPRR protein tyrosine phosphatase, receptor type, R
PVT1 Pvt1 oncogene (non-protein coding)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RIN3 Ras and Rab interactor 3
RRBP1 ribosome binding protein 1
SEC14L2 SEC14-like 2 (S. cerevisiae)
SETD1B SET domain containing 1B
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SOX13 SRY (sex determining region Y)-box 13
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SRSF5 serine/arginine-rich splicing factor 5
ST7L suppression of tumorigenicity 7 like
SUGP1 SURP and G patch domain containing 1
TAGLN3 transgelin 3
TAOK2 TAO kinase 2
TAOK3 TAO kinase 3
TAPBP TAP binding protein (tapasin)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
THRB thyroid hormone receptor, beta
TINAGL1 tubulointerstitial nephritis antigen-like 1
TJAP1 tight junction associated protein 1 (peripheral)
TMCC1 transmembrane and coiled-coil domain family 1
TNS1 tensin 1
TREX1 three prime repair exonuclease 1
WDR25 WD repeat domain 25
WWOX WW domain containing oxidoreductase
WWP2 WW domain containing E3 ubiquitin protein ligase 2
YTHDC1 YTH domain containing 1
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF197 zinc finger protein 197
ZNF222 zinc finger protein 222
ZNF276 zinc finger protein 276
ZNF442 zinc finger protein 442
ZNF529 zinc finger protein 529
ZNF768 zinc finger protein 768
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADGRF1 adhesion G protein-coupled receptor F1
AHDC1 AT hook, DNA binding motif, containing 1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANKRD40 ankyrin repeat domain 40
BAG4 BCL2-associated athanogene 4
BDNF brain-derived neurotrophic factor
BSPRY B-box and SPRY domain containing
C19ORF40 chromosome 19 open reading frame 40
C1ORF159 chromosome 1 open reading frame 159
C1QTNF1 C1q and tumor necrosis factor related protein 1
CAPN5 calpain 5
CARD8 caspase recruitment domain family, member 8
CBY1 chibby homolog 1 (Drosophila)
CDH7 cadherin 7, type 2
CDON cell adhesion associated, oncogene regulated
CLDN14 claudin 14
CLDN15 claudin 15
CLEC10A C-type lectin domain family 10, member A
CLSPN claspin
CPED1 cadherin-like and PC-esterase domain containing 1
CRYBA2 crystallin, beta A2
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DSPP dentin sialophosphoprotein
EDC4 enhancer of mRNA decapping 4
ELSPBP1 epididymal sperm binding protein 1
EN2 engrailed homeobox 2
EPHA4 EPH receptor A4
EPPK1 epiplakin 1
FAIM Fas apoptotic inhibitory molecule
FBXL15 F-box and leucine-rich repeat protein 15
FGD6 FYVE, RhoGEF and PH domain containing 6
FHOD1 formin homology 2 domain containing 1
GAMT guanidinoacetate N-methyltransferase
GATA6 GATA binding protein 6
GPRASP1 G protein-coupled receptor associated sorting protein 1
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AM histone cluster 1, H2am
HOXB9 homeobox B9
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
KRT34 keratin 34, type I
LINS lines homolog (Drosophila)
LRRC61 leucine rich repeat containing 61
MANBA mannosidase, beta A, lysosomal
MB myoglobin
MLYCD malonyl-CoA decarboxylase
MT1M metallothionein 1M
MYL5 myosin, light chain 5, regulatory
MYLK myosin light chain kinase
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NOTCH1 notch 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NT5DC3 5'-nucleotidase domain containing 3
PARP16 poly (ADP-ribose) polymerase family, member 16
PHKG2 phosphorylase kinase, gamma 2 (testis)
PLEKHA6 pleckstrin homology domain containing, family A member 6
PRKX protein kinase, X-linked
PTDSS2 phosphatidylserine synthase 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RAB20 RAB20, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RPP25 ribonuclease P/MRP 25kDa subunit
RUNX1-IT1 RUNX1 intronic transcript 1
SCEL sciellin
SECTM1 secreted and transmembrane 1
SERTAD3 SERTA domain containing 3
SLC12A8 solute carrier family 12, member 8
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNTA1 syntrophin, alpha 1
SOX12 SRY (sex determining region Y)-box 12
SPEG SPEG complex locus
SRD5A3 steroid 5 alpha-reductase 3
STARD5 StAR-related lipid transfer (START) domain containing 5
TMC5 transmembrane channel-like 5
TMEM156 transmembrane protein 156
TMEM177 transmembrane protein 177
TMEM183A transmembrane protein 183A
TMEM212 transmembrane protein 212
TMEM53 transmembrane protein 53
TMEM8B transmembrane protein 8B
TSC22D4 TSC22 domain family, member 4
UNC119 unc-119 homolog (C. elegans)
URGCP upregulator of cell proliferation
USP27X ubiquitin specific peptidase 27, X-linked
VEZT vezatin, adherens junctions transmembrane protein
WWC2 WW and C2 domain containing 2
ZFAND3 zinc finger, AN1-type domain 3
ZMAT5 zinc finger, matrin-type 5
ZNF385D zinc finger protein 385D
ZNF480 zinc finger protein 480
ZNF571 zinc finger protein 571
ZNF629 zinc finger protein 629
ZNF668 zinc finger protein 668
ZNF862 zinc finger protein 862