jnk cascade Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description An intracellular protein kinase cascade containing at least a JNK (a MAPK), a JNKK (a MAPKK) and a JUN3K (a MAP3K). The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell. (Gene Ontology, GO_0007254)
External Link http://amigo.geneontology.org/amigo/term/GO:0007254
Similar Terms
Downloads & Tools

Genes

50 genes participating in the jnk cascade biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ADORA2B adenosine A2b receptor
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
DUSP10 dual specificity phosphatase 10
DUSP19 dual specificity phosphatase 19
DUSP28 dual specificity phosphatase 28
DUSP9 dual specificity phosphatase 9
GPS1 G protein pathway suppressor 1
GPS2 G protein pathway suppressor 2
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK4 interleukin-1 receptor-associated kinase 4
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K10 mitogen-activated protein kinase kinase kinase 10
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAPK10 mitogen-activated protein kinase 10
MAPK8 mitogen-activated protein kinase 8
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MAPK9 mitogen-activated protein kinase 9
MINK1 misshapen-like kinase 1
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RB1CC1 RB1-inducible coiled-coil 1
RIPK2 receptor-interacting serine-threonine kinase 2
ROR2 receptor tyrosine kinase-like orphan receptor 2
RPS27A ribosomal protein S27a
SH2D3A SH2 domain containing 3A
SH2D3C SH2 domain containing 3C
STRADB STE20-related kinase adaptor beta
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TNF tumor necrosis factor
TNFRSF19 tumor necrosis factor receptor superfamily, member 19
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIB1 tribbles pseudokinase 1
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C