iswi-type complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Any nuclear protein complex that contains an ATPase subunit of the imitation switch (ISWI) family. ISWI ATPases are involved in assembling chromatin and in sliding and spacing nucleosomes to regulate transcription of nuclear RNA polymerases I, II, and III and also DNA replication, recombination and repair. (Gene Ontology, GO_0031010)
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Genes

237 proteins co-occuring with the iswi-type complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 1.76432
BAZ1B bromodomain adjacent to zinc finger domain, 1B 1.39684
WIPF2 WAS/WASL interacting protein family, member 2 1.22984
CHRAC1 chromatin accessibility complex 1 1.05842
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit 1.05337
H3F3A H3 histone, family 3A 1.03029
H3F3B H3 histone, family 3B (H3.3B) 1.03029
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 1.01585
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.993183
FOXA1 forkhead box A1 0.975166
ZNF668 zinc finger protein 668 0.893943
MYBBP1A MYB binding protein (P160) 1a 0.864447
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.862149
BAZ2A bromodomain adjacent to zinc finger domain, 2A 0.86123
CECR2 cat eye syndrome chromosome region, candidate 2 0.852042
EYA1 EYA transcriptional coactivator and phosphatase 1 0.851124
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.807065
MUM1 melanoma associated antigen (mutated) 1 0.797895
ZNF154 zinc finger protein 154 0.788733
WAC WW domain containing adaptor with coiled-coil 0.782784
BPTF bromodomain PHD finger transcription factor 0.747737
ARID3A AT rich interactive domain 3A (BRIGHT-like) 0.736464
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.723026
EYA3 EYA transcriptional coactivator and phosphatase 3 0.684207
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) 0.664232
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.642286
EPM2AIP1 EPM2A (laforin) interacting protein 1 0.633732
SPO11 SPO11 meiotic protein covalently bound to DSB 0.609086
PKNOX1 PBX/knotted 1 homeobox 1 0.603174
IRF4 interferon regulatory factor 4 0.584686
YEATS4 YEATS domain containing 4 0.580086
HDAC9 histone deacetylase 9 0.576747
TTF1 transcription termination factor, RNA polymerase I 0.576329
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.574244
CHD1 chromodomain helicase DNA binding protein 1 0.551012
FOXJ2 forkhead box J2 0.543176
ALX1 ALX homeobox 1 0.52225
PAX5 paired box 5 0.509604
SETD2 SET domain containing 2 0.504318
HIST2H2AC histone cluster 2, H2ac 0.497015
HIST2H2AA3 histone cluster 2, H2aa3 0.497015
HIST2H2AA4 histone cluster 2, H2aa4 0.497015
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 0.4865
VNN1 vanin 1 0.484483
SATB1 SATB homeobox 1 0.484079
RAG2 recombination activating gene 2 0.474822
DNAH8 dynein, axonemal, heavy chain 8 0.472813
SPI1 Spi-1 proto-oncogene 0.471609
H2AFX H2A histone family, member X 0.468001
CPEB1 cytoplasmic polyadenylation element binding protein 1 0.465998
PBRM1 polybromo 1 0.465598
EBF1 early B-cell factor 1 0.462398
KAT2A K(lysine) acetyltransferase 2A 0.45641
LIF leukemia inhibitory factor 0.452029
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae) 0.45004
JCHAIN joining chain of multimeric IgA and IgM 0.448451
CD4 CD4 molecule 0.438937
ING5 inhibitor of growth family, member 5 0.436565
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.434591
RUNX1 runt-related transcription factor 1 0.424745
TRAC T cell receptor alpha constant 0.421212
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 0.419252
FOSL2 FOS-like antigen 2 0.416511
DEK DEK proto-oncogene 0.415337
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 0.409089
HIST2H4A histone cluster 2, H4a 0.405193
HIST2H4B histone cluster 2, H4b 0.405193
HIST1H4C histone cluster 1, H4c 0.405193
HIST1H4B histone cluster 1, H4b 0.405193
HIST1H4K histone cluster 1, H4k 0.405193
HIST1H4D histone cluster 1, H4d 0.405193
HIST1H4I histone cluster 1, H4i 0.405193
HIST1H4J histone cluster 1, H4j 0.405193
HIST1H4H histone cluster 1, H4h 0.405193
HIST1H4A histone cluster 1, H4a 0.405193
HIST1H4E histone cluster 1, H4e 0.405193
HIST1H4F histone cluster 1, H4f 0.405193
HIST1H4L histone cluster 1, H4l 0.404804
HIST4H4 histone cluster 4, H4 0.404804
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 0.402081
NPAS2 neuronal PAS domain protein 2 0.401693
CTCF CCCTC-binding factor (zinc finger protein) 0.395485
PRDM9 PR domain containing 9 0.395485
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 0.39471
BMP10 bone morphogenetic protein 10 0.393162
NAP1L1 nucleosome assembly protein 1-like 1 0.389682
GATA3 GATA binding protein 3 0.389682
PRMT5 protein arginine methyltransferase 5 0.388137
ADAM23 ADAM metallopeptidase domain 23 0.387751
ATM ATM serine/threonine kinase 0.382739
TLX1 T-cell leukemia homeobox 1 0.373516
KAT5 K(lysine) acetyltransferase 5 0.369301
AVPR1A arginine vasopressin receptor 1A 0.368919
PAX2 paired box 2 0.368153
HDAC10 histone deacetylase 10 0.365859
IL7R interleukin 7 receptor 0.361277
BATF basic leucine zipper transcription factor, ATF-like 0.357847
MYH1 myosin, heavy chain 1, skeletal muscle, adult 0.355944
USP2 ubiquitin specific peptidase 2 0.354802
PIGM phosphatidylinositol glycan anchor biosynthesis, class M 0.351382
RSF1 remodeling and spacing factor 1 0.348725
MARS methionyl-tRNA synthetase 0.348346
ADAM28 ADAM metallopeptidase domain 28 0.347587
STRA13 stimulated by retinoic acid 13 0.344556
MYOD1 myogenic differentiation 1 0.339639
GATA2 GATA binding protein 2 0.325702
KDM4A lysine (K)-specific demethylase 4A 0.324201
OXA1L oxidase (cytochrome c) assembly 1-like 0.318953
ESR1 estrogen receptor 1 0.315586
CXXC1 CXXC finger protein 1 0.314465
SIRT7 sirtuin 7 0.30924
SFTPA2 surfactant protein A2 0.308122
PTF1A pancreas specific transcription factor, 1a 0.307004
FZD3 frizzled class receptor 3 0.301797
H2AFY H2A histone family, member Y 0.289569
HMGB1 high mobility group box 1 0.28846
KLF9 Kruppel-like factor 9 0.281821
GHRHR growth hormone releasing hormone receptor 0.281085
PSIP1 PC4 and SFRS1 interacting protein 1 0.278877
TBX21 T-box 21 0.276671
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.275569
SIRT1 sirtuin 1 0.275202
APITD1 apoptosis-inducing, TAF9-like domain 1 0.273734
IRAK3 interleukin-1 receptor-associated kinase 3 0.271533
HLTF helicase-like transcription factor 0.270434
MYOG myogenin (myogenic factor 4) 0.265311
IPO13 importin 13 0.263485
CRTC2 CREB regulated transcription coactivator 2 0.262025
HOXB4 homeobox B4 0.252927
GMNN geminin, DNA replication inhibitor 0.247854
HIST1H1D histone cluster 1, H1d 0.24424
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 0.235966
CHD7 chromodomain helicase DNA binding protein 7 0.235607
TET2 tet methylcytosine dioxygenase 2 0.229532
GSAP gamma-secretase activating protein 0.228108
NIT1 nitrilase 1 0.221378
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.217511
NDN necdin, melanoma antigen (MAGE) family member 0.216111
IL22 interleukin 22 0.215063
AICDA activation-induced cytidine deaminase 0.210894
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.205059
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.205059
HDAC1 histone deacetylase 1 0.202684
RAB25 RAB25, member RAS oncogene family 0.202346
FOXP3 forkhead box P3 0.201672
KAT7 K(lysine) acetyltransferase 7 0.195353
SPTB spectrin, beta, erythrocytic 0.194371
WIF1 WNT inhibitory factor 1 0.191135
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.191135
HPSE heparanase 0.190495
NUPR1 nuclear protein, transcriptional regulator, 1 0.18859
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.185777
KLF4 Kruppel-like factor 4 (gut) 0.185469
BCL6 B-cell CLL/lymphoma 6 0.18516
TCF7 transcription factor 7 (T-cell specific, HMG-box) 0.184853
LGALS4 lectin, galactoside-binding, soluble, 4 0.184547
CIITA class II, major histocompatibility complex, transactivator 0.183328
SOX6 SRY (sex determining region Y)-box 6 0.182122
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 0.180634
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.178011
TP53 tumor protein p53 0.173003
THBS4 thrombospondin 4 0.171937
EP300 E1A binding protein p300 0.168598
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.167366
SIX1 SIX homeobox 1 0.166643
HDAC11 histone deacetylase 11 0.166643
CDX2 caudal type homeobox 2 0.166167
MEIS1 Meis homeobox 1 0.165932
CREB1 cAMP responsive element binding protein 1 0.164089
LMO2 LIM domain only 2 (rhombotin-like 1) 0.162546
SFTPA1 surfactant protein A1 0.160254
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.159856
HIST1H2AD histone cluster 1, H2ad 0.159658
HIST1H2AJ histone cluster 1, H2aj 0.159658
H2AFJ H2A histone family, member J 0.159658
HIST1H2AM histone cluster 1, H2am 0.159462
HIST1H2AH histone cluster 1, H2ah 0.159462
KMT2B lysine (K)-specific methyltransferase 2B 0.159268
HIST1H2AG histone cluster 1, H2ag 0.158882
H2AFY2 H2A histone family, member Y2 0.157943
HIST1H2AB histone cluster 1, H2ab 0.15776
HIST1H2AE histone cluster 1, H2ae 0.15776
HIST1H1B histone cluster 1, H1b 0.157578
H2AFV H2A histone family, member V 0.157578
SOCS3 suppressor of cytokine signaling 3 0.156688
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein 0.127508
FANCI Fanconi anemia, complementation group I 0.126319
CENPA centromere protein A 0.126093
UHRF1 ubiquitin-like with PHD and ring finger domains 1 0.124527
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1 0.124048
WASH7P WAS protein family homolog 7 pseudogene 0.123902
WASH6P WAS protein family homolog 6 pseudogene 0.123806
WASH1 WAS protein family homolog 1 0.123732
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.123626
BRWD1 bromodomain and WD repeat domain containing 1 0.123387
MCPH1 microcephalin 1 0.12331
RBBP4 retinoblastoma binding protein 4 0.122816
RPA2 replication protein A2, 32kDa 0.122492
SLBP stem-loop binding protein 0.121264
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.121264
NFE2 nuclear factor, erythroid 2 0.119603
CDA cytidine deaminase 0.117537
FANCD2 Fanconi anemia, complementation group D2 0.117373
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.116042
UBTF upstream binding transcription factor, RNA polymerase I 0.114853
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.113709
CNTLN centlein, centrosomal protein 0.111318
MGAM maltase-glucoamylase 0.109253
NOTCH1 notch 1 0.109229
WAS Wiskott-Aldrich syndrome 0.109203
MYB v-myb avian myeloblastosis viral oncogene homolog 0.108751
KAT2B K(lysine) acetyltransferase 2B 0.10793
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.107641
H2AFB1 H2A histone family, member B1 0.106839
H2AFB2 H2A histone family, member B2 0.106595
RAD51 RAD51 recombinase 0.10607
ATP11A ATPase, class VI, type 11A 0.103515
RB1 retinoblastoma 1 0.10235
PCNA proliferating cell nuclear antigen 0.102287
CHD4 chromodomain helicase DNA binding protein 4 0.101432
TOP1 topoisomerase (DNA) I 0.096997
PARP1 poly (ADP-ribose) polymerase 1 0.096711
LYZ lysozyme 0.092558
DAD1 defender against cell death 1 0.091497
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.091299
ARG2 arginase 2 0.091219
ARID1A AT rich interactive domain 1A (SWI-like) 0.09114
JUN jun proto-oncogene 0.090981
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.09066
KLF2 Kruppel-like factor 2 0.09066
RAG1 recombination activating gene 1 0.09066
CR2 complement component (3d/Epstein Barr virus) receptor 2 0.090094
METTL13 methyltransferase like 13 0.089811
NFYB nuclear transcription factor Y, beta 0.089811
OTX2 orthodenticle homeobox 2 0.088742
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 0.088159
SP1 Sp1 transcription factor 0.087909