isoxicam-7028 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the isoxicam-7028 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ADCY9 adenylate cyclase 9
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
ARL1 ADP-ribosylation factor-like 1
ARL4C ADP-ribosylation factor-like 4C
ARMCX4 armadillo repeat containing, X-linked 4
ARRB1 arrestin, beta 1
BMP2K BMP2 inducible kinase
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CAPZB capping protein (actin filament) muscle Z-line, beta
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC186 coiled-coil domain containing 186
CD302 CD302 molecule
CD83 CD83 molecule
CEP72 centrosomal protein 72kDa
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CUL9 cullin 9
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DNAL4 dynein, axonemal, light chain 4
DPYSL4 dihydropyrimidinase-like 4
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ELOVL5 ELOVL fatty acid elongase 5
ERN2 endoplasmic reticulum to nucleus signaling 2
EXO5 exonuclease 5
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FDPS farnesyl diphosphate synthase
FRMD4A FERM domain containing 4A
FZD7 frizzled class receptor 7
GADD45B growth arrest and DNA-damage-inducible, beta
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GTPBP4 GTP binding protein 4
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HHEX hematopoietically expressed homeobox
HIST1H2AM histone cluster 1, H2am
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL17RC interleukin 17 receptor C
IQCG IQ motif containing G
IRF5 interferon regulatory factor 5
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIAA0930 KIAA0930
KITLG KIT ligand
KRIT1 KRIT1, ankyrin repeat containing
L2HGDH L-2-hydroxyglutarate dehydrogenase
LINC00115 long intergenic non-protein coding RNA 115
LRRC23 leucine rich repeat containing 23
LRRC41 leucine rich repeat containing 41
LTC4S leukotriene C4 synthase
LUZP1 leucine zipper protein 1
LY6D lymphocyte antigen 6 complex, locus D
LZTR1 leucine-zipper-like transcription regulator 1
MAP1A microtubule-associated protein 1A
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MEGF9 multiple EGF-like-domains 9
MFSD11 major facilitator superfamily domain containing 11
NASP nuclear autoantigenic sperm protein (histone-binding)
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NF2 neurofibromin 2 (merlin)
NIPAL2 NIPA-like domain containing 2
OASL 2'-5'-oligoadenylate synthetase-like
PAPPA2 pappalysin 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PKNOX1 PBX/knotted 1 homeobox 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAB35 RAB35, member RAS oncogene family
RAD50 RAD50 homolog (S. cerevisiae)
RANGAP1 Ran GTPase activating protein 1
RNF2 ring finger protein 2
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS2 ribosomal protein S2
SCAI suppressor of cancer cell invasion
SELL selectin L
SETD1A SET domain containing 1A
SIDT2 SID1 transmembrane family, member 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC38A7 solute carrier family 38, member 7
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
ST7 suppression of tumorigenicity 7
STK4 serine/threonine kinase 4
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBCD tubulin folding cofactor D
TCHH trichohyalin
TRABD TraB domain containing
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VDAC3 voltage-dependent anion channel 3
YIPF2 Yip1 domain family, member 2
ZNF324 zinc finger protein 324
ZNF552 zinc finger protein 552

decreased expression

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABHD14A abhydrolase domain containing 14A
ABHD17B abhydrolase domain containing 17B
ADCK3 aarF domain containing kinase 3
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGAP11A Rho GTPase activating protein 11A
ARMC6 armadillo repeat containing 6
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
C11ORF95 chromosome 11 open reading frame 95
C14ORF132 chromosome 14 open reading frame 132
C16ORF59 chromosome 16 open reading frame 59
C3ORF52 chromosome 3 open reading frame 52
C5ORF45 chromosome 5 open reading frame 45
C9ORF40 chromosome 9 open reading frame 40
CA11 carbonic anhydrase XI
CALCOCO1 calcium binding and coiled-coil domain 1
CCNE1 cyclin E1
CCNT1 cyclin T1
CDC25A cell division cycle 25A
CDR2L cerebellar degeneration-related protein 2-like
CEP85 centrosomal protein 85kDa
CLSPN claspin
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COL9A2 collagen, type IX, alpha 2
CTAGE9 CTAGE family, member 9
CTBS chitobiase, di-N-acetyl-
CXORF56 chromosome X open reading frame 56
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFNA3 ephrin-A3
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EVL Enah/Vasp-like
FAM193B family with sequence similarity 193, member B
FANCE Fanconi anemia, complementation group E
FURIN furin (paired basic amino acid cleaving enzyme)
GAS8 growth arrest-specific 8
GATA6 GATA binding protein 6
GLCE glucuronic acid epimerase
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BI histone cluster 1, H2bi
HPS6 Hermansky-Pudlak syndrome 6
IFT140 intraflagellar transport 140
IFT22 intraflagellar transport 22
INCENP inner centromere protein antigens 135/155kDa
IQSEC2 IQ motif and Sec7 domain 2
IRAK4 interleukin-1 receptor-associated kinase 4
IRF7 interferon regulatory factor 7
IRF9 interferon regulatory factor 9
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KRI1 KRI1 homolog (S. cerevisiae)
LIN7B lin-7 homolog B (C. elegans)
LINS lines homolog (Drosophila)
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRC61 leucine rich repeat containing 61
MBTD1 mbt domain containing 1
MFAP2 microfibrillar-associated protein 2
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MT1E metallothionein 1E
MTG1 mitochondrial ribosome-associated GTPase 1
NARFL nuclear prelamin A recognition factor-like
NDRG1 N-myc downstream regulated 1
NKAIN1 Na+/K+ transporting ATPase interacting 1
NUP62CL nucleoporin 62kDa C-terminal like
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PARD6A par-6 family cell polarity regulator alpha
PCDHA6 protocadherin alpha 6
PGM1 phosphoglucomutase 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRMT7 protein arginine methyltransferase 7
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
RBL1 retinoblastoma-like 1
REEP4 receptor accessory protein 4
RFX7 regulatory factor X, 7
RNF216 ring finger protein 216
SCAP SREBF chaperone
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SMA4 glucuronidase, beta pseudogene
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNIP1 Smad nuclear interacting protein 1
SOX3 SRY (sex determining region Y)-box 3
STX5 syntaxin 5
SYT17 synaptotagmin XVII
THRAP3 thyroid hormone receptor associated protein 3
TMEM2 transmembrane protein 2
TNRC6B trinucleotide repeat containing 6B
TPCN1 two pore segment channel 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAPPC12 trafficking protein particle complex 12
TTLL1 tubulin tyrosine ligase-like family member 1
XYLT2 xylosyltransferase II
YIPF3 Yip1 domain family, member 3
ZFAND3 zinc finger, AN1-type domain 3
ZNF586 zinc finger protein 586
ZNF611 zinc finger protein 611
ZNF668 zinc finger protein 668