ischemic stroke Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0002140
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Genes

119 genes associated with the ischemic stroke phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
ZFHX3 zinc finger homeobox 3 1.21853
FMNL2 formin-like 2 1.14684
ARL6IP6 ADP-ribosylation factor-like 6 interacting protein 6 1.11638
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 1.1002
PAPPA2 pappalysin 2 1.1002
PHF20L1 PHD finger protein 20-like 1 1.09003
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 1.08224
SPSB4 splA/ryanodine receptor domain and SOCS box containing 4 1.07729
ABHD2 abhydrolase domain containing 2 1.0674
UBE2Z ubiquitin-conjugating enzyme E2Z 1.06722
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.04365
PTPRD protein tyrosine phosphatase, receptor type, D 1.02868
TG thyroglobulin 1.02775
NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14 1.02593
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit 1.02289
EEF1DP3 eukaryotic translation elongation factor 1 delta pseudogene 3 1.01768
C1ORF177 chromosome 1 open reading frame 177 1.00733
A2ML1 alpha-2-macroglobulin-like 1 0.997692
PDGFRL platelet-derived growth factor receptor-like 0.99698
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.993537
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 0.986868
CELA2A chymotrypsin-like elastase family, member 2A 0.969142
TRAPPC11 trafficking protein particle complex 11 0.969142
SPATA5 spermatogenesis associated 5 0.967782
DLG2 discs, large homolog 2 (Drosophila) 0.964112
RYR2 ryanodine receptor 2 (cardiac) 0.960972
CDH13 cadherin 13 0.945118
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.939122
NCAM1 neural cell adhesion molecule 1 0.929673
TMEM181 transmembrane protein 181 0.924776
TMPRSS15 transmembrane protease, serine 15 0.922853
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 0.914419
DOCK4 dedicator of cytokinesis 4 0.911485
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 0.905507
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 0.903602
CNTNAP2 contactin associated protein-like 2 0.887931
PTPRT protein tyrosine phosphatase, receptor type, T 0.887592
ADCY8 adenylate cyclase 8 (brain) 0.887255
FNDC3B fibronectin type III domain containing 3B 0.883951
TNR tenascin R 0.8703
LUZP2 leucine zipper protein 2 0.8703
TMEM71 transmembrane protein 71 0.869471
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.86797
UMODL1 uromodulin-like 1 0.866894
CCDC3 coiled-coil domain containing 3 0.865569
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.865306
PRMT8 protein arginine methyltransferase 8 0.861653
TPTE2P1 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 1 0.86025
ADAM17 ADAM metallopeptidase domain 17 0.859619
KIAA0020 KIAA0020 0.858372
ZNF366 zinc finger protein 366 0.858124
SGK1 serum/glucocorticoid regulated kinase 1 0.857632
SLC5A9 solute carrier family 5 (sodium/sugar cotransporter), member 9 0.85426
BTLA B and T lymphocyte associated 0.850449
ANO3 anoctamin 3 0.847343
NIN ninein (GSK3B interacting protein) 0.847343
LINC00474 long intergenic non-protein coding RNA 474 0.845298
NLRP9 NLR family, pyrin domain containing 9 0.827192
RGS13 regulator of G-protein signaling 13 0.825497
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.815267
PPAPDC1A phosphatidic acid phosphatase type 2 domain containing 1A 0.795881
PPT2 palmitoyl-protein thioesterase 2 0.789144
DGCR2 DiGeorge syndrome critical region gene 2 0.784773
PZP pregnancy-zone protein 0.776638
MCC mutated in colorectal cancers 0.77499
HHAT hedgehog acyltransferase 0.766212
ANO6 anoctamin 6 0.761395
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.751857
OTOG otogelin 0.748581
GLIS1 GLIS family zinc finger 1 0.727711
BCL2L2 BCL2-like 2 0.725675
CSMD3 CUB and Sushi multiple domains 3 0.718688
UBA2 ubiquitin-like modifier activating enzyme 2 0.714303
SULF1 sulfatase 1 0.710801
RBM20 RNA binding motif protein 20 0.708638
BCAN brevican 0.704969
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.690274
GRID1 glutamate receptor, ionotropic, delta 1 0.673945
ARHGAP44 Rho GTPase activating protein 44 0.670488
HEPACAM2 HEPACAM family member 2 0.669642
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.667971
UBA6 ubiquitin-like modifier activating enzyme 6 0.655029
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.650987
GRM7 glutamate receptor, metabotropic 7 0.64937
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 0.636409
STK32B serine/threonine kinase 32B 0.636183
IRF8 interferon regulatory factor 8 0.632852
THRB thyroid hormone receptor, beta 0.630475
TMEM165 transmembrane protein 165 0.625067
PIGR polymeric immunoglobulin receptor 0.619932
MBL2 mannose-binding lectin (protein C) 2, soluble 0.616311
PRR5L proline rich 5 like 0.61421
SOX5 SRY (sex determining region Y)-box 5 0.613082
CHSY3 chondroitin sulfate synthase 3 0.612337
C10ORF35 chromosome 10 open reading frame 35 0.608689
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.605341
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 0.604478
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 0.602943
PKNOX1 PBX/knotted 1 homeobox 1 0.602268
CCDC132 coiled-coil domain containing 132 0.599776
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.599449
JAKMIP2 janus kinase and microtubule interacting protein 2 0.596707
HUNK hormonally up-regulated Neu-associated kinase 0.594972
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 0.592349
CASC15 cancer susceptibility candidate 15 (non-protein coding) 0.585631
SPEG SPEG complex locus 0.585631
CETP cholesteryl ester transfer protein, plasma 0.582099
ARHGAP6 Rho GTPase activating protein 6 0.58198
DRD2 dopamine receptor D2 0.579049
ARHGAP24 Rho GTPase activating protein 24 0.57745
ADGRB3 adhesion G protein-coupled receptor B3 0.577224
BFSP1 beaded filament structural protein 1, filensin 0.573253
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.572823
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.544615
LLGL2 lethal giant larvae homolog 2 (Drosophila) 0.481126
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.471832
SPTB spectrin, beta, erythrocytic 0.446809
KCNK17 potassium channel, two pore domain subfamily K, member 17 0.446809
KCNIP4 Kv channel interacting protein 4 0.445816