iron Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

214 genes co-occuring with the biological term iron in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ACO1 aconitase 1, soluble
ACO2 aconitase 2, mitochondrial
ACP5 acid phosphatase 5, tartrate resistant
ACVR1 activin A receptor, type I
ADIPOQ adiponectin, C1Q and collagen domain containing
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHSP alpha hemoglobin stabilizing protein
ALAS2 5'-aminolevulinate synthase 2
ALB albumin
ALDOA aldolase A, fructose-bisphosphate
ALKBH3 alkB, alkylation repair homolog 3 (E. coli)
ALKBH7 alkB, alkylation repair homolog 7 (E. coli)
ALOX5 arachidonate 5-lipoxygenase
AP1M2 adaptor-related protein complex 1, mu 2 subunit
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
ATM ATM serine/threonine kinase
ATP13A2 ATPase type 13A2
B2M beta-2-microglobulin
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like
BDH2 3-hydroxybutyrate dehydrogenase, type 2
BGLAP bone gamma-carboxyglutamate (gla) protein
BMP2 bone morphogenetic protein 2
BMP6 bone morphogenetic protein 6
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRCA1 breast cancer 1, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTBD9 BTB (POZ) domain containing 9
C19ORF12 chromosome 19 open reading frame 12
CA1 carbonic anhydrase I
CA2 carbonic anhydrase II
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CALR calreticulin
CBS cystathionine-beta-synthase
CCL2 chemokine (C-C motif) ligand 2
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CETP cholesteryl ester transfer protein, plasma
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIT1 chitinase 1 (chitotriosidase)
CHMP2B charged multivesicular body protein 2B
CIAO1 cytosolic iron-sulfur assembly component 1
CISD1 CDGSH iron sulfur domain 1
COASY CoA synthase
CP ceruloplasmin (ferroxidase)
CUBN cubilin (intrinsic factor-cobalamin receptor)
CXCL8 chemokine (C-X-C motif) ligand 8
CYBA cytochrome b-245, alpha polypeptide
CYBRD1 cytochrome b reductase 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DGUOK deoxyguanosine kinase
DMRT1 doublesex and mab-3 related transcription factor 1
DOHH deoxyhypusine hydroxylase/monooxygenase
EIF3A eukaryotic translation initiation factor 3, subunit A
ELANE elastase, neutrophil expressed
EPAS1 endothelial PAS domain protein 1
EPO erythropoietin
F2 coagulation factor II (thrombin)
FA2H fatty acid 2-hydroxylase
FAM96A family with sequence similarity 96, member A
FAM96B family with sequence similarity 96, member B
FAS Fas cell surface death receptor
FBXL5 F-box and leucine-rich repeat protein 5
FDX1 ferredoxin 1
FECH ferrochelatase
FGF23 fibroblast growth factor 23
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FN1 fibronectin 1
FTH1 ferritin, heavy polypeptide 1
FTL ferritin, light polypeptide
FTMT ferritin mitochondrial
FXN frataxin
FYN FYN proto-oncogene, Src family tyrosine kinase
GAST gastrin
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GDF15 growth differentiation factor 15
GHRL ghrelin/obestatin prepropeptide
GLRX3 glutaredoxin 3
GLRX5 glutaredoxin 5
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
HAMP hepcidin antimicrobial peptide
HBA1 hemoglobin, alpha 1
HBA2 hemoglobin, alpha 2
HBB hemoglobin, beta
HEPH hephaestin
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HFE hemochromatosis
HFE2 hemochromatosis type 2 (juvenile)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-G major histocompatibility complex, class I, G
HMOX1 heme oxygenase 1
HP haptoglobin
HPX hemopexin
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
IDO2 indoleamine 2,3-dioxygenase 2
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL10 interleukin 10
IL1B interleukin 1, beta
IL6 interleukin 6
INS insulin
IREB2 iron-responsive element binding protein 2
ISCU iron-sulfur cluster assembly enzyme
ITCH itchy E3 ubiquitin protein ligase
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK1 Janus kinase 1
JMJD6 jumonji domain containing 6
KDM4C lysine (K)-specific demethylase 4C
LCN2 lipocalin 2
LEAP2 liver expressed antimicrobial peptide 2
LGALS3 lectin, galactoside-binding, soluble, 3
LTF lactotransferrin
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MB myoglobin
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEIS1 Meis homeobox 1
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR210 microRNA 210
MIR485 microRNA 485
MIRLET7D microRNA let-7d
MMP1 matrix metallopeptidase 1
MPO myeloperoxidase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAMPT nicotinamide phosphoribosyltransferase
NCOA4 nuclear receptor coactivator 4
NDFIP1 Nedd4 family interacting protein 1
NDRG1 N-myc downstream regulated 1
NFE2L2 nuclear factor, erythroid 2-like 2
NOS2 nitric oxide synthase 2, inducible
NOX1 NADPH oxidase 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1
OPA1 optic atrophy 1 (autosomal dominant)
PAH phenylalanine hydroxylase
PANK2 pantothenate kinase 2
PCBP1 poly(rC) binding protein 1
PCBP2 poly(rC) binding protein 2
PCSK7 proprotein convertase subtilisin/kexin type 7
PHB prohibitin
PHYH phytanoyl-CoA 2-hydroxylase
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PON1 paraoxonase 1
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRNP prion protein
PROM1 prominin 1
PSENEN presenilin enhancer gamma secretase subunit
RASD2 RASD family, member 2
RBP4 retinol binding protein 4, plasma
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SF3B1 splicing factor 3b, subunit 1, 155kDa
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SMAD7 SMAD family member 7
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SRSF7 serine/arginine-rich splicing factor 7
SSB Sjogren syndrome antigen B (autoantigen La)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STEAP2 STEAP family member 2, metalloreductase
STEAP3 STEAP family member 3, metalloreductase
STIP1 stress-induced phosphoprotein 1
TF transferrin
TFR2 transferrin receptor 2
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TLR4 toll-like receptor 4
TMPRSS6 transmembrane protease, serine 6
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TP53 tumor protein p53
TWSG1 twisted gastrulation BMP signaling modulator 1
UBE2D1 ubiquitin-conjugating enzyme E2D 1
VCAM1 vascular cell adhesion molecule 1
VDAC2 voltage-dependent anion channel 2
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WDR45 WD repeat domain 45
WRN Werner syndrome, RecQ helicase-like