ionomycin-882 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the ionomycin-882 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACE angiotensin I converting enzyme
ANG angiogenin, ribonuclease, RNase A family, 5
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ATF3 activating transcription factor 3
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
CCL21 chemokine (C-C motif) ligand 21
CD4 CD4 molecule
CD96 CD96 molecule
CFB complement factor B
CGA glycoprotein hormones, alpha polypeptide
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
COL14A1 collagen, type XIV, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL9A3 collagen, type IX, alpha 3
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CSHL1 chorionic somatomammotropin hormone-like 1
CSN2 casein beta
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DICER1 dicer 1, ribonuclease type III
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EPAS1 endothelial PAS domain protein 1
EPB41 erythrocyte membrane protein band 4.1
ETV5 ets variant 5
FKBP14 FK506 binding protein 14, 22 kDa
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GLRX glutaredoxin (thioltransferase)
GRM1 glutamate receptor, metabotropic 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HNMT histamine N-methyltransferase
HOXD13 homeobox D13
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IL36RN interleukin 36 receptor antagonist
INHBE inhibin, beta E
ITGB7 integrin, beta 7
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
LAMA4 laminin, alpha 4
LARP6 La ribonucleoprotein domain family, member 6
LPAR3 lysophosphatidic acid receptor 3
LPAR4 lysophosphatidic acid receptor 4
LZTFL1 leucine zipper transcription factor-like 1
MANF mesencephalic astrocyte-derived neurotrophic factor
MAP1A microtubule-associated protein 1A
MAP1B microtubule-associated protein 1B
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MSI1 musashi RNA-binding protein 1
MYT1L myelin transcription factor 1-like
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPVF neuropeptide VF precursor
NRG2 neuregulin 2
NUPR1 nuclear protein, transcriptional regulator, 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PCDH12 protocadherin 12
PCDHB17P protocadherin beta 17 pseudogene
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PER1 period circadian clock 1
PKD2L2 polycystic kidney disease 2-like 2
PLXNC1 plexin C1
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRO2964 uncharacterized protein PRO2964
PRRX2 paired related homeobox 2
PYY peptide YY
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RBM12B-AS1 RBM12B antisense RNA 1
RCAN1 regulator of calcineurin 1
RCE1 Ras converting CAAX endopeptidase 1
RNASE4 ribonuclease, RNase A family, 4
RSU1 Ras suppressor protein 1
SCEL sciellin
SCUBE3 signal peptide, CUB domain, EGF-like 3
SDF2L1 stromal cell-derived factor 2-like 1
SEC24D SEC24 family member D
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLA Src-like-adaptor
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPATA1 spermatogenesis associated 1
SUGP1 SURP and G patch domain containing 1
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TEF thyrotrophic embryonic factor
TES testin LIM domain protein
TGFA transforming growth factor, alpha
THBD thrombomodulin
TRIM2 tripartite motif containing 2
TRIM31 tripartite motif containing 31
TSPY1 testis specific protein, Y-linked 1
TSPYL2 TSPY-like 2
TUBA3C tubulin, alpha 3c
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZNF365 zinc finger protein 365

decreased expression

Symbol Name
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ADGRL2 adhesion G protein-coupled receptor L2
AKR1C3 aldo-keto reductase family 1, member C3
AMIGO2 adhesion molecule with Ig-like domain 2
ANKRD36B ankyrin repeat domain 36B
ANKRD49 ankyrin repeat domain 49
AP1AR adaptor-related protein complex 1 associated regulatory protein
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATP13A3 ATPase type 13A3
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAG2 BCL2-associated athanogene 2
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C1ORF56 chromosome 1 open reading frame 56
C3ORF52 chromosome 3 open reading frame 52
C5ORF30 chromosome 5 open reading frame 30
C9ORF3 chromosome 9 open reading frame 3
CA2 carbonic anhydrase II
CCNL2 cyclin L2
CDT1 chromatin licensing and DNA replication factor 1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPE centromere protein E, 312kDa
CEP83 centrosomal protein 83kDa
CLK4 CDC-like kinase 4
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CNOT6 CCR4-NOT transcription complex, subunit 6
COCH cochlin
COPS7B COP9 signalosome subunit 7B
COQ6 coenzyme Q6 monooxygenase
CORO1A coronin, actin binding protein, 1A
CYB5R1 cytochrome b5 reductase 1
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
E2F8 E2F transcription factor 8
EXOSC9 exosome component 9
FAM69A family with sequence similarity 69, member A
FANCL Fanconi anemia, complementation group L
FASTKD5 FAST kinase domains 5
FOXC1 forkhead box C1
FUZ fuzzy planar cell polarity protein
FZD3 frizzled class receptor 3
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GLB1L2 galactosidase, beta 1-like 2
GLMN glomulin, FKBP associated protein
GPALPP1 GPALPP motifs containing 1
GPR19 G protein-coupled receptor 19
GTF2I general transcription factor IIi
HCFC2 host cell factor C2
HOXC11 homeobox C11
HP1BP3 heterochromatin protein 1, binding protein 3
HSPA2 heat shock 70kDa protein 2
HSPA4L heat shock 70kDa protein 4-like
IGSF3 immunoglobulin superfamily, member 3
LMNB1 lamin B1
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MSH2 mutS homolog 2
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NAP1L2 nucleosome assembly protein 1-like 2
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NDRG4 NDRG family member 4
NES nestin
OSBPL11 oxysterol binding protein-like 11
PCSK7 proprotein convertase subtilisin/kexin type 7
PLEKHA5 pleckstrin homology domain containing, family A member 5
PP14571 uncharacterized LOC100130449
PRMT7 protein arginine methyltransferase 7
PRR15L proline rich 15-like
PTGES2 prostaglandin E synthase 2
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RBM38 RNA binding motif protein 38
RIT1 Ras-like without CAAX 1
RNF38 ring finger protein 38
RPS10P5 ribosomal protein S10 pseudogene 5
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SALL2 spalt-like transcription factor 2
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC25A40 solute carrier family 25, member 40
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SOAT1 sterol O-acyltransferase 1
STBD1 starch binding domain 1
SUOX sulfite oxidase
SUSD6 sushi domain containing 6
TESK2 testis-specific kinase 2
TP53I3 tumor protein p53 inducible protein 3
TRAF5 TNF receptor-associated factor 5
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
URGCP upregulator of cell proliferation
USP6NL USP6 N-terminal like
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
ZBTB10 zinc finger and BTB domain containing 10
ZNF266 zinc finger protein 266
ZNF443 zinc finger protein 443
ZNF692 zinc finger protein 692