ion Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

285 genes co-occuring with the biological term ion in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADCY7 adenylate cyclase 7
ADORA2A adenosine A2a receptor
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AHCYL1 adenosylhomocysteinase-like 1
ALPP alkaline phosphatase, placental
ANG angiogenin, ribonuclease, RNase A family, 5
ANO2 anoctamin 2, calcium activated chloride channel
ANO6 anoctamin 6
ANTXR2 anthrax toxin receptor 2
ANXA4 annexin A4
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APP amyloid beta (A4) precursor protein
AQP1 aquaporin 1 (Colton blood group)
AQP4 aquaporin 4
AQP5 aquaporin 5
ARF6 ADP-ribosylation factor 6
ARG1 arginase 1
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASIC1 acid sensing (proton gated) ion channel 1
ASIC2 acid sensing (proton gated) ion channel 2
ASIC3 acid sensing (proton gated) ion channel 3
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
B2M beta-2-microglobulin
BCHE butyrylcholinesterase
BEST1 bestrophin 1
BIRC5 baculoviral IAP repeat containing 5
BVES blood vessel epicardial substance
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QC complement component 1, q subcomponent, C chain
CA1 carbonic anhydrase I
CA2 carbonic anhydrase II
CA6 carbonic anhydrase VI
CA9 carbonic anhydrase IX
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CALHM1 calcium homeostasis modulator 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAPN2 calpain 2, (m/II) large subunit
CATSPER1 cation channel, sperm associated 1
CAV1 caveolin 1, caveolae protein, 22kDa
CCR6 chemokine (C-C motif) receptor 6
CCS copper chaperone for superoxide dismutase
CD38 CD38 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK2 cyclin-dependent kinase 2
CDK5 cyclin-dependent kinase 5
CDKN2A cyclin-dependent kinase inhibitor 2A
CERS2 ceramide synthase 2
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLCA1 chloride channel accessory 1
CLCN2 chloride channel, voltage-sensitive 2
CLCN4 chloride channel, voltage-sensitive 4
CLCN5 chloride channel, voltage-sensitive 5
CLDN2 claudin 2
CLDN4 claudin 4
CLIC1 chloride intracellular channel 1
CLIC3 chloride intracellular channel 3
CNGA3 cyclic nucleotide gated channel alpha 3
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COL1A1 collagen, type I, alpha 1
COPS5 COP9 signalosome subunit 5
CORO1A coronin, actin binding protein, 1A
CP ceruloplasmin (ferroxidase)
CRHR1 corticotropin releasing hormone receptor 1
CRHR2 corticotropin releasing hormone receptor 2
CTH cystathionine gamma-lyase
CTNNBIP1 catenin, beta interacting protein 1
CTRC chymotrypsin C (caldecrin)
CXCL12 chemokine (C-X-C motif) ligand 12
DLG1 discs, large homolog 1 (Drosophila)
DLG4 discs, large homolog 4 (Drosophila)
DMC1 DNA meiotic recombinase 1
DNASE1 deoxyribonuclease I
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DYT2 dystonia 2, torsion (autosomal recessive)
DYT7 dystonia 7, torsion (autosomal dominant)
EGFR epidermal growth factor receptor
ENKUR enkurin, TRPC channel interacting protein
EPS8 epidermal growth factor receptor pathway substrate 8
F2RL1 coagulation factor II (thrombin) receptor-like 1
FBXW4 F-box and WD repeat domain containing 4
FECH ferrochelatase
FEN1 flap structure-specific endonuclease 1
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLNA filamin A, alpha
FPR2 formyl peptide receptor 2
FXYD1 FXYD domain containing ion transport regulator 1
FXYD2 FXYD domain containing ion transport regulator 2
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GCH1 GTP cyclohydrolase 1
GJB2 gap junction protein, beta 2, 26kDa
GJD2 gap junction protein, delta 2, 36kDa
GLRA1 glycine receptor, alpha 1
GLRA3 glycine receptor, alpha 3
GLRB glycine receptor, beta
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPR39 G protein-coupled receptor 39
GRIK1 glutamate receptor, ionotropic, kainate 1
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GUCA2A guanylate cyclase activator 2A (guanylin)
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HDAC8 histone deacetylase 8
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HOXD9 homeobox D9
HPX hemopexin
HRG histidine-rich glycoprotein
HTN3 histatin 3
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HVCN1 hydrogen voltage gated channel 1
IAPP islet amyloid polypeptide
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IFNG interferon, gamma
IGFBP1 insulin-like growth factor binding protein 1
IL6 interleukin 6
INS insulin
ITGA1 integrin, alpha 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB7 integrin, beta 7
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCNK4 potassium channel, two pore domain subfamily K, member 4
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KCNT2 potassium channel, sodium activated subfamily T, member 2
KIF5B kinesin family member 5B
KL klotho
KLHL3 kelch-like family member 3
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LIN7B lin-7 homolog B (C. elegans)
MBP myelin basic protein
MCOLN1 mucolipin 1
MCOLN3 mucolipin 3
MMP8 matrix metallopeptidase 8
MT1E metallothionein 1E
MT2A metallothionein 2A
MYOCD myocardin
NDRG2 NDRG family member 2
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NGF nerve growth factor (beta polypeptide)
NLRC5 NLR family, CARD domain containing 5
NLRP3 NLR family, pyrin domain containing 3
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPY2R neuropeptide Y receptor Y2
OPN4 opsin 4
OPRD1 opioid receptor, delta 1
ORAI1 ORAI calcium release-activated calcium modulator 1
ORAI3 ORAI calcium release-activated calcium modulator 3
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PARP1 poly (ADP-ribose) polymerase 1
PCNA proliferating cell nuclear antigen
PIEZO2 piezo-type mechanosensitive ion channel component 2
PITX2 paired-like homeodomain 2
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene)
PKD1L3 polycystic kidney disease 1-like 3
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLN phospholamban
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PON1 paraoxonase 1
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PRKCA protein kinase C, alpha
PRKCZ protein kinase C, zeta
PRNP prion protein
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSPH phosphoserine phosphatase
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTK2B protein tyrosine kinase 2 beta
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RGS14 regulator of G-protein signaling 14
RNASEH1 ribonuclease H1
RTN1 reticulon 1
RYR1 ryanodine receptor 1 (skeletal)
RYR2 ryanodine receptor 2 (cardiac)
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN2A sodium channel, voltage gated, type II alpha subunit
SCN4A sodium channel, voltage gated, type IV alpha subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SIGMAR1 sigma non-opioid intracellular receptor 1
SIRT2 sirtuin 2
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC26A9 solute carrier family 26 (anion exchanger), member 9
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SRF serum response factor (c-fos serum response element-binding transcription factor)
STIM1 stromal interaction molecule 1
STOM stomatin
STOML1 stomatin (EPB72)-like 1
STOML2 stomatin (EPB72)-like 2
STRA6 stimulated by retinoic acid 6
TAC3 tachykinin 3
TF transferrin
TFRC transferrin receptor
THAP1 THAP domain containing, apoptosis associated protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLX2 T-cell leukemia homeobox 2
TNNC1 troponin C type 1 (slow)
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP2B topoisomerase (DNA) II beta 180kDa
TOR1A torsin family 1, member A (torsin A)
TP53BP1 tumor protein p53 binding protein 1
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPC7 transient receptor potential cation channel, subfamily C, member 7
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPM5 transient receptor potential cation channel, subfamily M, member 5
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSC22D3 TSC22 domain family, member 3
TYR tyrosinase
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UMOD uromodulin
VDAC1 voltage-dependent anion channel 1
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WNK1 WNK lysine deficient protein kinase 1
WNK3 WNK lysine deficient protein kinase 3
WNK4 WNK lysine deficient protein kinase 4
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZFP36 ZFP36 ring finger protein