intrinsic component of endoplasmic reticulum membrane Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The component of the endoplasmic reticulum membrane consisting of gene products and protein complexes that have some covalently attached part (e.g. peptide sequence or GPI anchor), which spans or is embedded in one or both leaflets of the membrane. (Gene Ontology, GO_0031227)
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Genes

116 proteins localized to the intrinsic component of endoplasmic reticulum membrane cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
GPAA1 glycosylphosphatidylinositol anchor attachment 1 0.663342
EMC9 ER membrane protein complex subunit 9 0.663342
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.663342
CREB3 cAMP responsive element binding protein 3 0.663342
CLN3 ceroid-lipofuscinosis, neuronal 3 0.663342
ASPH aspartate beta-hydroxylase 0.663342
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase 0.663342
DCSTAMP dendrocyte expressed seven transmembrane protein 0.663342
EMC7 ER membrane protein complex subunit 7 0.663342
ERN1 endoplasmic reticulum to nucleus signaling 1 0.663342
EMC10 ER membrane protein complex subunit 10 0.663342
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.663342
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 0.663342
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 0.663342
RTN4 reticulon 4 0.663342
RTN2 reticulon 2 0.663342
EMC8 ER membrane protein complex subunit 8 0.663342
EMC3 ER membrane protein complex subunit 3 0.663342
INSIG1 insulin induced gene 1 0.663342
G6PC glucose-6-phosphatase, catalytic subunit 0.663342
SREBF2 sterol regulatory element binding transcription factor 2 0.663342
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.663342
SPPL2B signal peptide peptidase like 2B 0.663342
SPPL2C signal peptide peptidase like 2C 0.663342
SPPL2A signal peptide peptidase like 2A 0.663342
DERL3 derlin 3 0.663342
DERL2 derlin 2 0.663342
DERL1 derlin 1 0.663342
EMC4 ER membrane protein complex subunit 4 0.663342
EMC6 ER membrane protein complex subunit 6 0.663342
PGAP3 post-GPI attachment to proteins 3 0.663342
EMC1 ER membrane protein complex subunit 1 0.663342
EMC2 ER membrane protein complex subunit 2 0.663342
ANKLE2 ankyrin repeat and LEM domain containing 2 0.663342
SPPL3 signal peptide peptidase like 3 0.663342
SAMD8 sterile alpha motif domain containing 8 0.663342
VIMP VCP-interacting membrane selenoprotein 0.663342
MMGT1 membrane magnesium transporter 1 0.663342
ELOVL4 ELOVL fatty acid elongase 4 0.663342
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 0.663342
DOLK dolichol kinase 0.663342
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.663342
ESYT2 extended synaptotagmin-like protein 2 0.663342
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.663342
RTN1 reticulon 1 0.663342
UBXN8 UBX domain protein 8 0.663342
INSIG2 insulin induced gene 2 0.663342
STIM1 stromal interaction molecule 1 0.663342
SGPL1 sphingosine-1-phosphate lyase 1 0.663342
TAPBP TAP binding protein (tapasin) 0.663342
ACER3 alkaline ceramidase 3 0.663342
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) 0.663342
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 0.663342
TECR trans-2,3-enoyl-CoA reductase 0.663342
SARAF store-operated calcium entry-associated regulatory factor 0.663342
ESYT3 extended synaptotagmin-like protein 3 0.663342
PIGK phosphatidylinositol glycan anchor biosynthesis, class K 0.663342
ESYT1 extended synaptotagmin-like protein 1 0.663342
PIGS phosphatidylinositol glycan anchor biosynthesis, class S 0.663342
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 0.663342
ELOVL1 ELOVL fatty acid elongase 1 0.663342
HM13 histocompatibility (minor) 13 0.663342
PIGU phosphatidylinositol glycan anchor biosynthesis, class U 0.663342
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.237908
HLA-DRA major histocompatibility complex, class II, DR alpha 0.237908
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1 0.237908
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.237908
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.237908
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 0.237908
DOLPP1 dolichyldiphosphatase 1 0.237908
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 0.237908
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 0.237908
WFS1 Wolfram syndrome 1 (wolframin) 0.237908
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.237908
RHBDD1 rhomboid domain containing 1 0.237908
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 0.237908
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.237908
EXT1 exostosin glycosyltransferase 1 0.237908
CALR calreticulin 0.237908
HLA-F major histocompatibility complex, class I, F 0.237908
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.237908
HLA-G major histocompatibility complex, class I, G 0.237908
HLA-A major histocompatibility complex, class I, A 0.237908
HLA-B major histocompatibility complex, class I, B 0.237908
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 0.237908
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.237908
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.237908
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.237908
HLA-C major histocompatibility complex, class I, C 0.237908
HLA-DRB3 major histocompatibility complex, class II, DR beta 3 0.237908
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.237908
FITM2 fat storage-inducing transmembrane protein 2 0.237908
CANX calnexin 0.237908
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.237908
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.237908
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.237908
BCAP31 B-cell receptor-associated protein 31 0.237908
MBOAT4 membrane bound O-acyltransferase domain containing 4 0.237908
HLA-E major histocompatibility complex, class I, E 0.237908
DGAT2 diacylglycerol O-acyltransferase 2 0.098109
ELOVL6 ELOVL fatty acid elongase 6 0.03318
RNF180 ring finger protein 180 0.03318
UPK2 uroplakin 2 0.03318
EXTL3 exostosin-like glycosyltransferase 3 0.03318
RRBP1 ribosome binding protein 1 0.03318
PORCN porcupine homolog (Drosophila) 0.03318
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.03318
EXTL1 exostosin-like glycosyltransferase 1 0.03318
LRMP lymphoid-restricted membrane protein 0.03318
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) 0.03318
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 0.03318
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 0.03318
EXTL2 exostosin-like glycosyltransferase 2 0.03318
FITM1 fat storage-inducing transmembrane protein 1 0.03318
EXT2 exostosin glycosyltransferase 2 0.03318
FKBP8 FK506 binding protein 8, 38kDa 0.03318