intrinsic asthma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An asthma that is triggered by factors not related to allergies such as anxiety, stress, exercise, cold air, dry air, hyperventilation, smoke, viruses, chemical irritants, autonomic imbalance, hormonal deficiencies and psychogenic influences. It is characterized by airway obstruction and inflammation that is at least partially reversible with medication. The symptoms include coughing, wheezing, shortness of breath or rapid breathing, and chest tightness. (Human Disease Ontology, DOID_9360)
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Genes

28 genes co-occuring with the disease intrinsic asthma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ADAM2 ADAM metallopeptidase domain 2 0.965825
RNASE3 ribonuclease, RNase A family, 3 0.654858
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 0.60342
GPX5 glutathione peroxidase 5 0.571495
GPX4 glutathione peroxidase 4 0.568386
GPX1 glutathione peroxidase 1 0.552463
CD4 CD4 molecule 0.523045
CCL8 chemokine (C-C motif) ligand 8 0.517649
IGHV3-9 immunoglobulin heavy variable 3-9 0.500379
CD68 CD68 molecule 0.486266
IL4 interleukin 4 0.471846
PRF1 perforin 1 (pore forming protein) 0.449571
NCAM1 neural cell adhesion molecule 1 0.441666
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 0.427015
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.390025
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.37555
KRT18 keratin 18, type I 0.285802
GIF gastric intrinsic factor (vitamin B synthesis) 0.264077
CMA1 chymase 1, mast cell 0.247852
HLA-A major histocompatibility complex, class I, A 0.235616
DPT dermatopontin 0.233878
CCL13 chemokine (C-C motif) ligand 13 0.230063
IL10 interleukin 10 0.226952
IL13 interleukin 13 0.219398
NGFR nerve growth factor receptor 0.20229
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 0.182375
CCL2 chemokine (C-C motif) ligand 2 0.177029
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.173057