intestinal polyp Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description A discrete abnormal tissue mass that protrudes into the lumen of the intestine and is attached to the intestinal wall either by a stalk, pedunculus, or a broad base. (Human Phenotype Ontology, HP_0005266)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0005266
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Genes

37 genes associated with the intestinal polyp phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
ACVRL1 activin A receptor type II-like 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
APC adenomatous polyposis coli
AXIN2 axin 2
BMPR1A bone morphogenetic protein receptor, type IA
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
CEP57 centrosomal protein 57kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
ECE1 endothelin converting enzyme 1
EDN3 endothelin 3
EDNRB endothelin receptor type B
ENG endoglin
GDF2 growth differentiation factor 2
GDNF glial cell derived neurotrophic factor
GNAS GNAS complex locus
GREM1 gremlin 1, DAN family BMP antagonist
KLLN killin, p53-regulated DNA replication inhibitor
L1CAM L1 cell adhesion molecule
MLH1 mutL homolog 1
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MUTYH mutY homolog
NRTN neurturin
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PTCH1 patched 1
PTCH2 patched 2
PTEN phosphatase and tensin homolog
RET ret proto-oncogene
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SMAD4 SMAD family member 4
STK11 serine/threonine kinase 11
SUFU suppressor of fused homolog (Drosophila)