intestinal obstruction Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

376 genes co-occuring with the disease intestinal obstruction in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.79841
MLN motilin 1.58582
OPRM1 opioid receptor, mu 1 1.55823
APOLD1 apolipoprotein L domain containing 1 1.37817
ALB albumin 1.2944
GHRL ghrelin/obestatin prepropeptide 1.29178
MLNR motilin receptor 1.27214
RET ret proto-oncogene 1.25471
TUBE1 tubulin, epsilon 1 1.25254
EDNRB endothelin receptor type B 1.24515
SST somatostatin 1.21998
EDN3 endothelin 3 1.12151
ISX intestine-specific homeobox 1.08034
CRP C-reactive protein, pentraxin-related 1.02903
ACHE acetylcholinesterase (Yt blood group) 1.01047
PHF20 PHD finger protein 20 0.985164
TYMP thymidine phosphorylase 0.958287
ZNF185 zinc finger protein 185 (LIM domain) 0.944521
GCG glucagon 0.930828
CCK cholecystokinin 0.927519
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.918024
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 0.890898
SOX10 SRY (sex determining region Y)-box 10 0.888848
MPO myeloperoxidase 0.876966
MBOAT4 membrane bound O-acyltransferase domain containing 4 0.864274
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.863865
IGHV1-2 immunoglobulin heavy variable 1-2 0.854859
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.852402
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.851992
THEG theg spermatid protein 0.851173
LAX1 lymphocyte transmembrane adaptor 1 0.826589
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.814283
SRCIN1 SRC kinase signaling inhibitor 1 0.806488
TMEM164 transmembrane protein 164 0.805667
EPB41L5 erythrocyte membrane protein band 4.1 like 5 0.795821
GHSR growth hormone secretagogue receptor 0.792951
SLC26A9 solute carrier family 26 (anion exchanger), member 9 0.78066
ACTG2 actin, gamma 2, smooth muscle, enteric 0.778613
SOCS7 suppressor of cytokine signaling 7 0.762678
CD79A CD79a molecule, immunoglobulin-associated alpha 0.761047
GAST gastrin 0.758193
ALPPL2 alkaline phosphatase, placental-like 2 0.756156
ALPP alkaline phosphatase, placental 0.755749
ALPL alkaline phosphatase, liver/bone/kidney 0.754934
PPY pancreatic polypeptide 0.752898
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.736649
PYY peptide YY 0.730976
CALCA calcitonin-related polypeptide alpha 0.728952
NOS2 nitric oxide synthase 2, inducible 0.725311
NXT2 nuclear transport factor 2-like export factor 2 0.72127
RGAG1 retrotransposon gag domain containing 1 0.71925
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) 0.707961
AVP arginine vasopressin 0.701526
TTR transthyretin 0.699116
TEPP testis, prostate and placenta expressed 0.695103
CD34 CD34 molecule 0.683493
SMTN smoothelin 0.682693
NTS neurotensin 0.681894
NOS1 nitric oxide synthase 1 (neuronal) 0.6791
FOS FBJ murine osteosarcoma viral oncogene homolog 0.676706
TRAPPC6B trafficking protein particle complex 6B 0.671925
LCT lactase 0.66755
GDNF glial cell derived neurotrophic factor 0.665563
TAC1 tachykinin, precursor 1 0.6608
THEMIS thymocyte selection associated 0.654463
STK11 serine/threonine kinase 11 0.653276
F2 coagulation factor II (thrombin) 0.646559
IL6 interleukin 6 0.641433
VIP vasoactive intestinal peptide 0.636708
CHRM3 cholinergic receptor, muscarinic 3 0.630027
APLF aprataxin and PNKP like factor 0.629242
CAMP cathelicidin antimicrobial peptide 0.623751
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 0.621792
L3MBTL3 l(3)mbt-like 3 (Drosophila) 0.617486
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.615921
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 0.614356
STK10 serine/threonine kinase 10 0.60225
CRH corticotropin releasing hormone 0.575383
MFF mitochondrial fission factor 0.573439
LCK LCK proto-oncogene, Src family tyrosine kinase 0.550522
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.550522
PTCH1 patched 1 0.548583
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.548583
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 0.545481
MYLK myosin light chain kinase 0.52729
GUCY2F guanylate cyclase 2F, retinal 0.52343
ENDOU endonuclease, polyU-specific 0.519961
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 0.51842
PPT2 palmitoyl-protein thioesterase 2 0.515725
ENO2 enolase 2 (gamma, neuronal) 0.501527
F3 coagulation factor III (thromboplastin, tissue factor) 0.496175
INS insulin 0.494266
VEGFA vascular endothelial growth factor A 0.489311
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.485885
ELAVL3 ELAV like neuron-specific RNA binding protein 3 0.479047
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 0.479047
LYZ lysozyme 0.478668
PER1 period circadian clock 1 0.474119
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5 0.467306
MGAM maltase-glucoamylase 0.462016
IFITM1 interferon induced transmembrane protein 1 0.455978
F8 coagulation factor VIII, procoagulant component 0.452208
BCHE butyrylcholinesterase 0.450324
TNF tumor necrosis factor 0.447687
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 0.4443
CCL2 chemokine (C-C motif) ligand 2 0.425514
LHFPL5 lipoma HMGIC fusion partner-like 5 0.420266
LCOR ligand dependent nuclear receptor corepressor 0.419517
KRT7 keratin 7, type II 0.419142
SPINK1 serine peptidase inhibitor, Kazal type 1 0.418768
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.416896
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.411657
HES2 hes family bHLH transcription factor 2 0.410535
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.409414
SYP synaptophysin 0.404184
HPN hepsin 0.392629
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.387794
PNLIP pancreatic lipase 0.386308
ICAM1 intercellular adhesion molecule 1 0.386308
DAPK3 death-associated protein kinase 3 0.385565
B2M beta-2-microglobulin 0.379997
TRIM37 tripartite motif containing 37 0.375179
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 0.367779
DAAM2 dishevelled associated activator of morphogenesis 2 0.362239
GGT1 gamma-glutamyltransferase 1 0.359657
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.353395
IL1B interleukin 1, beta 0.350084
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.348614
KLK3 kallikrein-related peptidase 3 0.347511
ZCCHC7 zinc finger, CCHC domain containing 7 0.346042
ABRA actin binding Rho activating protein 0.344207
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.342372
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 0.33944
CLCA1 chloride channel accessory 1 0.337242
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) 0.333218
RPIA ribose 5-phosphate isomerase A 0.332852
CHRM4 cholinergic receptor, muscarinic 4 0.32993
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 0.32774
FAM3C family with sequence similarity 3, member C 0.327375
PRAMEF12 PRAME family member 12 0.32009
IARS isoleucyl-tRNA synthetase 0.318999
CRHR1 corticotropin releasing hormone receptor 1 0.318272
ELSPBP1 epididymal sperm binding protein 1 0.317545
CD4 CD4 molecule 0.312464
HES5 hes family bHLH transcription factor 5 0.312464
GLRA1 glycine receptor, alpha 1 0.307757
MRO maestro 0.30631
FLNA filamin A, alpha 0.30631
MNX1 motor neuron and pancreas homeobox 1 0.305587
PAAF1 proteasomal ATPase-associated factor 1 0.304142
PTDSS1 phosphatidylserine synthase 1 0.298371
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like 0.297651
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 0.295132
KCNIP4 Kv channel interacting protein 4 0.294053
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.292257
NF1 neurofibromin 1 0.291898
HOXB5 homeobox B5 0.289744
PGRMC1 progesterone receptor membrane component 1 0.289027
CDX2 caudal type homeobox 2 0.285802
LARS leucyl-tRNA synthetase 0.284728
PRSS1 protease, serine, 1 (trypsin 1) 0.279724
DMP1 dentin matrix acidic phosphoprotein 1 0.27794
ACSL4 acyl-CoA synthetase long-chain family member 4 0.27794
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 0.277584
FGF10 fibroblast growth factor 10 0.27687
TUBB2A tubulin, beta 2A class IIa 0.273308
TECR trans-2,3-enoyl-CoA reductase 0.272953
AKR1D1 aldo-keto reductase family 1, member D1 0.27153
MYLK3 myosin light chain kinase 3 0.269398
TLR4 toll-like receptor 4 0.268332
CLMP CXADR-like membrane protein 0.264077
AAAS achalasia, adrenocortical insufficiency, alacrimia 0.256652
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 0.256299
NCAM1 neural cell adhesion molecule 1 0.256299
CD68 CD68 molecule 0.253831
FOXQ1 forkhead box Q1 0.253831
CLDN1 claudin 1 0.252422
GPR55 G protein-coupled receptor 55 0.251015
MYD88 myeloid differentiation primary response 88 0.247852
FABP9 fatty acid binding protein 9, testis 0.244696
GAN gigaxonin 0.241895
KRT20 keratin 20, type I 0.241196
CLDN7 claudin 7 0.239799
TUBB tubulin, beta class I 0.238752
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.237009
TAS1R1 taste receptor, type 1, member 1 0.235616
TBPL1 TBP-like 1 0.227642
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 0.226607
SH3GL1 SH3-domain GRB2-like 1 0.216672
FLOT2 flotillin 2 0.216332
SMS spermine synthase 0.214636
IGLV2-8 immunoglobulin lambda variable 2-8 0.213621
HMOX1 heme oxygenase 1 0.210253
PFAS phosphoribosylformylglycinamidine synthase 0.202618
COIL coilin 0.201635
TPM1 tropomyosin 1 (alpha) 0.201308
POMC proopiomelanocortin 0.200331
TFF3 trefoil factor 3 (intestinal) 0.198064
DEFA5 defensin, alpha 5, Paneth cell-specific 0.197099
FAS Fas cell surface death receptor 0.197099
HBA1 hemoglobin, alpha 1 0.196459
IL2 interleukin 2 0.195183
SPAG7 sperm associated antigen 7 0.191719
PTPRC protein tyrosine phosphatase, receptor type, C 0.190168
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 0.187113
RRAS related RAS viral (r-ras) oncogene homolog 0.185313
HSF4 heat shock transcription factor 4 0.18472
UCN urocortin 0.180937
PROS1 protein S (alpha) 0.180652
FN1 fibronectin 1 0.180084
HBA2 hemoglobin, alpha 2 0.17896
SPRY2 sprouty homolog 2 (Drosophila) 0.177029
EGR1 early growth response 1 0.175411
AFP alpha-fetoprotein 0.173832
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.172038
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.171036
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.170299
SMC1A structural maintenance of chromosomes 1A 0.168617
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.166319
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.162306
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.161523
AADACL3 arylacetamide deacetylase-like 3 0.160574
GML glycosylphosphatidylinositol anchored molecule like 0.159838
PER3 period circadian clock 3 0.158605
MAT1A methionine adenosyltransferase I, alpha 0.143722
WDFY2 WD repeat and FYVE domain containing 2 0.141206
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.140024
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.136536
FOXF1 forkhead box F1 0.13647
HSPG2 heparan sulfate proteoglycan 2 0.135907
L1CAM L1 cell adhesion molecule 0.135846
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 0.135464
SCN5A sodium channel, voltage gated, type V alpha subunit 0.132432
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 0.132245
TSPAN8 tetraspanin 8 0.131141
EDA ectodysplasin A 0.130797
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.130144
CFAP74 cilia and flagella associated protein 74 0.129215
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 0.129171
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.128951
LIG3 ligase III, DNA, ATP-dependent 0.126829
CALCRL calcitonin receptor-like 0.125429
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.124233
IGLV3-10 immunoglobulin lambda variable 3-10 0.123744
CNR1 cannabinoid receptor 1 (brain) 0.122064
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 0.121797
TP73 tumor protein p73 0.121599
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.121365
ICT1 immature colon carcinoma transcript 1 0.121365
PPT1 palmitoyl-protein thioesterase 1 0.120771
FMN1 formin 1 0.120678
THEM4 thioesterase superfamily member 4 0.120543
IGLL5 immunoglobulin lambda-like polypeptide 5 0.120332
USF2 upstream transcription factor 2, c-fos interacting 0.119766
DLX5 distal-less homeobox 5 0.119687
MATN1 matrilin 1, cartilage matrix protein 0.119022
ALMS1 Alstrom syndrome protein 1 0.11896
NRP1 neuropilin 1 0.118939
MYOCD myocardin 0.118611
NIPBL Nipped-B homolog (Drosophila) 0.118463
PRODH proline dehydrogenase (oxidase) 1 0.117954
SFTPD surfactant protein D 0.117912
INVS inversin 0.117585
DNM2 dynamin 2 0.117497
GNS glucosamine (N-acetyl)-6-sulfatase 0.117432
SEMG1 semenogelin I 0.11741
ATXN7 ataxin 7 0.117388
CD59 CD59 molecule, complement regulatory protein 0.1173
AGA aspartylglucosaminidase 0.117104
MAP9 microtubule-associated protein 9 0.117013
CSN3 casein kappa 0.116923
CALB2 calbindin 2 0.116674
CRLF1 cytokine receptor-like factor 1 0.115963
PLG plasminogen 0.115706
NOTCH1 notch 1 0.115567
CELA1 chymotrypsin-like elastase family, member 1 0.115352
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.115159
CELA3B chymotrypsin-like elastase family, member 3B 0.114727
DPYSL5 dihydropyrimidinase-like 5 0.114679
THBS2 thrombospondin 2 0.114456
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 0.113479
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.113428
NONO non-POU domain containing, octamer-binding 0.112627
XDH xanthine dehydrogenase 0.111723
FDPS farnesyl diphosphate synthase 0.111208
NBPF10 neuroblastoma breakpoint family, member 10 0.111181
OR10R2 olfactory receptor, family 10, subfamily R, member 2 0.110905
TFAM transcription factor A, mitochondrial 0.110459
TACR1 tachykinin receptor 1 0.109953
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 0.109953
EPHB4 EPH receptor B4 0.109953
PITX2 paired-like homeodomain 2 0.109723
SALL4 spalt-like transcription factor 4 0.109493
ALK anaplastic lymphoma receptor tyrosine kinase 0.109435
EFNB2 ephrin-B2 0.108559
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 0.108441
FOXO4 forkhead box O4 0.107997
BMPR1A bone morphogenetic protein receptor, type IA 0.107784
UBE2K ubiquitin-conjugating enzyme E2K 0.107784
IL6R interleukin 6 receptor 0.107693
TPM3 tropomyosin 3 0.107663
LATS1 large tumor suppressor kinase 1 0.106123
ANO1 anoctamin 1, calcium activated chloride channel 0.104686
TNNI3 troponin I type 3 (cardiac) 0.104259
PGM1 phosphoglucomutase 1 0.103602
NCOA1 nuclear receptor coactivator 1 0.103198
PRSS3 protease, serine, 3 0.103097
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.102216
LRP2 low density lipoprotein receptor-related protein 2 0.101561
GPANK1 G patch domain and ankyrin repeats 1 0.101251
POLG polymerase (DNA directed), gamma 0.101074
PDGFB platelet-derived growth factor beta polypeptide 0.101039
TICAM2 toll-like receptor adaptor molecule 2 0.101003
MB myoglobin 0.10058
HLA-DMA major histocompatibility complex, class II, DM alpha 0.10058
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.10051
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.100122
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.100087
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.099546
HTRA1 HtrA serine peptidase 1 0.099293
ANOS1 anosmin 1 0.099113
DAXX death-domain associated protein 0.099041
ADAM17 ADAM metallopeptidase domain 17 0.098346
HP haptoglobin 0.098272
CMKLR1 chemerin chemokine-like receptor 1 0.098124
THY1 Thy-1 cell surface antigen 0.097903
KDR kinase insert domain receptor 0.097829
HPR haptoglobin-related protein 0.097682
RERE arginine-glutamic acid dipeptide (RE) repeats 0.097571
CLDN5 claudin 5 0.097045
ENO1 enolase 1, (alpha) 0.097008
PRRC2A proline-rich coiled-coil 2A 0.096367
MUTYH mutY homolog 0.09591
PTEN phosphatase and tensin homolog 0.095833
CD22 CD22 molecule 0.095564
MYH11 myosin, heavy chain 11, smooth muscle 0.095295
C1S complement component 1, s subcomponent 0.095103
TNNT2 troponin T type 2 (cardiac) 0.095103
SULF1 sulfatase 1 0.094911
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 0.094167
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.093971
SLC22A18 solute carrier family 22, member 18 0.093062
SCG2 secretogranin II 0.093022
CBS cystathionine-beta-synthase 0.092862
CS citrate synthase 0.092622
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.092622
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.092263
CDAN1 codanin 1 0.092183
GAL galanin/GMAP prepropeptide 0.09186
NPS neuropeptide S 0.09129
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 0.090965
HPGDS hematopoietic prostaglandin D synthase 0.090803
IFNL1 interferon, lambda 1 0.090516
ANK1 ankyrin 1, erythrocytic 0.090392
CXCL12 chemokine (C-X-C motif) ligand 12 0.090102
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.089895
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.089854
CLPS colipase, pancreatic 0.089813
AQP4 aquaporin 4 0.089565
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 0.089358
CTRL chymotrypsin-like 0.089234
ZNF135 zinc finger protein 135 0.089192
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.08894
FLT1 fms-related tyrosine kinase 1 0.08894
GAA glucosidase, alpha; acid 0.08852
ASRGL1 asparaginase like 1 0.088478
CRHR2 corticotropin releasing hormone receptor 2 0.088436
CSN1S1 casein alpha s1 0.088352
DIABLO diablo, IAP-binding mitochondrial protein 0.088268
NPTXR neuronal pentraxin receptor 0.088226
CDH5 cadherin 5, type 2 (vascular endothelium) 0.086783
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.086697
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 0.086484
FOXM1 forkhead box M1 0.086011
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.085535
MKKS McKusick-Kaufman syndrome 0.085535