intermediate filament cytoskeleton Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell. (Gene Ontology, GO_0045111)
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Genes

234 proteins localized to the intermediate filament cytoskeleton cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
NES nestin 0.663342
SYNM synemin, intermediate filament protein 0.663342
GPER1 G protein-coupled estrogen receptor 1 0.663342
KRT7 keratin 7, type II 0.663342
KRT5 keratin 5, type II 0.663342
NEFL neurofilament, light polypeptide 0.663342
FLG filaggrin 0.663342
KRT4 keratin 4, type II 0.663342
KRT18 keratin 18, type I 0.663342
VIM vimentin 0.663342
KRT13 keratin 13, type I 0.663342
KRT14 keratin 14, type I 0.663342
KRT6C keratin 6C, type II 0.663342
KRT16 keratin 16, type I 0.663342
KRT20 keratin 20, type I 0.663342
NEFH neurofilament, heavy polypeptide 0.663342
UPP2 uridine phosphorylase 2 0.663342
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 0.663342
KRT71 keratin 71, type II 0.663342
NCKIPSD NCK interacting protein with SH3 domain 0.663342
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 0.663342
KRT76 keratin 76, type II 0.663342
KRT10 keratin 10, type I 0.663342
KRT84 keratin 84, type II 0.663342
KRT82 keratin 82, type II 0.663342
DST dystonin 0.663342
KRT3 keratin 3, type II 0.663342
LMNA lamin A/C 0.663342
TLK2 tousled-like kinase 2 0.663342
NARF nuclear prelamin A recognition factor 0.237908
KRT2 keratin 2, type II 0.237908
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1 0.237908
LMNB1 lamin B1 0.237908
MDN1 MDN1, midasin homolog (yeast) 0.237908
SERGEF secretion regulating guanine nucleotide exchange factor 0.237908
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.237908
KRT8 keratin 8, type II 0.237908
MRPS23 mitochondrial ribosomal protein S23 0.237908
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.237908
CLIP1 CAP-GLY domain containing linker protein 1 0.237908
STAG2 stromal antigen 2 0.237908
SMNDC1 survival motor neuron domain containing 1 0.237908
CETN3 centrin, EF-hand protein, 3 0.237908
SMG7 SMG7 nonsense mediated mRNA decay factor 0.237908
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.237908
BCAS3 breast carcinoma amplified sequence 3 0.237908
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 0.237908
PCDHB4 protocadherin beta 4 0.237908
ZNF175 zinc finger protein 175 0.237908
EXOSC9 exosome component 9 0.237908
NDOR1 NADPH dependent diflavin oxidoreductase 1 0.237908
NSFL1C NSFL1 (p97) cofactor (p47) 0.237908
CTNS cystinosin, lysosomal cystine transporter 0.237908
CLK3 CDC-like kinase 3 0.237908
KRT19 keratin 19, type I 0.237908
C17ORF70 chromosome 17 open reading frame 70 0.237908
NEFM neurofilament, medium polypeptide 0.237908
KRT15 keratin 15, type I 0.237908
KRT17 keratin 17, type I 0.237908
PLEC plectin 0.237908
KRT80 keratin 80, type II 0.237908
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 0.237908
NUP35 nucleoporin 35kDa 0.237908
CCT8 chaperonin containing TCP1, subunit 8 (theta) 0.237908
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa 0.237908
CENPQ centromere protein Q 0.237908
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.237908
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.237908
IP6K2 inositol hexakisphosphate kinase 2 0.237908
USP10 ubiquitin specific peptidase 10 0.237908
GFAP glial fibrillary acidic protein 0.237908
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 0.237908
ADD1 adducin 1 (alpha) 0.237908
HOXA13 homeobox A13 0.237908
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.237908
PKN2 protein kinase N2 0.237908
BFSP1 beaded filament structural protein 1, filensin 0.237908
BFSP2 beaded filament structural protein 2, phakinin 0.237908
CHD3 chromodomain helicase DNA binding protein 3 0.237908
EIF1AD eukaryotic translation initiation factor 1A domain containing 0.237908
TACC1 transforming, acidic coiled-coil containing protein 1 0.237908
INA internexin neuronal intermediate filament protein, alpha 0.237908
DES desmin 0.237908
TCHP trichoplein, keratin filament binding 0.237908
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.237908
PRPH peripherin 0.237908
PKP1 plakophilin 1 0.237908
PNN pinin, desmosome associated protein 0.237908
KRT31 keratin 31, type I 0.237908
KRT24 keratin 24, type I 0.237908
SYNE2 spectrin repeat containing, nuclear envelope 2 0.237908
SYNE1 spectrin repeat containing, nuclear envelope 1 0.237908
ERCC5 excision repair cross-complementation group 5 0.237908
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 0.237908
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 0.237908
STXBP4 syntaxin binding protein 4 0.237908
LDLRAP1 low density lipoprotein receptor adaptor protein 1 0.098109
KRTAP13-4 keratin associated protein 13-4 0.098109
KRTAP13-1 keratin associated protein 13-1 0.098109
KRTAP20-1 keratin associated protein 20-1 0.098109
KRTAP13-2 keratin associated protein 13-2 0.098109
KRTAP13-3 keratin associated protein 13-3 0.098109
KRT28 keratin 28, type I 0.098109
KRTAP27-1 keratin associated protein 27-1 0.098109
PKP2 plakophilin 2 0.098109
KRT23 keratin 23, type I 0.098109
KRTAP21-1 keratin associated protein 21-1 0.098109
KRTAP20-2 keratin associated protein 20-2 0.098109
KRT27 keratin 27, type I 0.098109
KRT26 keratin 26, type I 0.098109
KRT25 keratin 25, type I 0.098109
KRTAP26-1 keratin associated protein 26-1 0.098109
IFFO1 intermediate filament family orphan 1 0.098109
KRTAP6-2 keratin associated protein 6-2 0.098109
KRTAP17-1 keratin associated protein 17-1 0.098109
KRTAP23-1 keratin associated protein 23-1 0.098109
KRT222 keratin 222, type II 0.098109
KRT38 keratin 38, type I 0.098109
KRTAP20-3 keratin associated protein 20-3 0.098109
KRTAP20-4 keratin associated protein 20-4 0.098109
SYNC syncoilin, intermediate filament protein 0.098109
KRTAP6-1 keratin associated protein 6-1 0.098109
KRTAP15-1 keratin associated protein 15-1 0.098109
KRT39 keratin 39, type I 0.098109
KRT32 keratin 32, type I 0.098109
KRT35 keratin 35, type I 0.098109
KRT34 keratin 34, type I 0.098109
KRT37 keratin 37, type I 0.098109
KRT36 keratin 36, type I 0.098109
KRT33B keratin 33B, type I 0.098109
KRT33A keratin 33A, type I 0.098109
LMNTD1 lamin tail domain containing 1 0.098109
KRTAP22-2 keratin associated protein 22-2 0.098109
KRTAP22-1 keratin associated protein 22-1 0.098109
KRTAP19-3 keratin associated protein 19-3 0.098109
KRTAP8-1 keratin associated protein 8-1 0.098109
KRTAP19-4 keratin associated protein 19-4 0.098109
KRTAP21-3 keratin associated protein 21-3 0.098109
KRT40 keratin 40, type I 0.098109
KRTAP25-1 keratin associated protein 25-1 0.098109
KRT12 keratin 12, type I 0.098109
KRTAP19-2 keratin associated protein 19-2 0.098109
KRTAP6-3 keratin associated protein 6-3 0.098109
KRTAP21-2 keratin associated protein 21-2 0.098109
KRTAP19-1 keratin associated protein 19-1 0.098109
KRT9 keratin 9, type I 0.098109
KRTAP19-8 keratin associated protein 19-8 0.098109
KRTAP19-6 keratin associated protein 19-6 0.098109
KRTAP19-7 keratin associated protein 19-7 0.098109
KRTAP19-5 keratin associated protein 19-5 0.098109
MYO5A myosin VA (heavy chain 12, myoxin) 0.03318
GJA1 gap junction protein, alpha 1, 43kDa 0.03318
KRT83 keratin 83, type II 0.03318
KRT85 keratin 85, type II 0.03318
KRT86 keratin 86, type II 0.03318
KRT78 keratin 78, type II 0.03318
KRTAP10-10 keratin associated protein 10-10 0.03318
KRTAP10-11 keratin associated protein 10-11 0.03318
KRTAP10-12 keratin associated protein 10-12 0.03318
KRT81 keratin 81, type II 0.03318
EIF6 eukaryotic translation initiation factor 6 0.03318
MNS1 meiosis-specific nuclear structural 1 0.03318
KRTAP4-11 keratin associated protein 4-11 0.03318
KRTAP4-12 keratin associated protein 4-12 0.03318
KRTAP10-9 keratin associated protein 10-9 0.03318
CASP14 caspase 14, apoptosis-related cysteine peptidase 0.03318
KRT79 keratin 79, type II 0.03318
KRTAP2-2 keratin associated protein 2-2 0.03318
NRP1 neuropilin 1 0.03318
DSP desmoplakin 0.03318
KRT6B keratin 6B, type II 0.03318
KRT6A keratin 6A, type II 0.03318
KRTAP24-1 keratin associated protein 24-1 0.03318
KRTAP2-3 keratin associated protein 2-3 0.03318
KRTAP5-10 keratin associated protein 5-10 0.03318
KRTAP5-11 keratin associated protein 5-11 0.03318
KRT1 keratin 1, type II 0.03318
LMNB2 lamin B2 0.03318
JUP junction plakoglobin 0.03318
KRTAP10-8 keratin associated protein 10-8 0.03318
KRTAP10-5 keratin associated protein 10-5 0.03318
KRTAP10-4 keratin associated protein 10-4 0.03318
IFFO2 intermediate filament family orphan 2 0.03318
KRTAP10-1 keratin associated protein 10-1 0.03318
KRTAP10-2 keratin associated protein 10-2 0.03318
KRTAP2-1 keratin associated protein 2-1 0.03318
KRTAP11-1 keratin associated protein 11-1 0.03318
KRTAP1-1 keratin associated protein 1-1 0.03318
KRTAP1-3 keratin associated protein 1-3 0.03318
KRTAP1-4 keratin associated protein 1-4 0.03318
KRTAP1-5 keratin associated protein 1-5 0.03318
NDEL1 nudE neurodevelopment protein 1-like 1 0.03318
KRTAP29-1 keratin associated protein 29-1 0.03318
KRTAP3-2 keratin associated protein 3-2 0.03318
KRTAP3-3 keratin associated protein 3-3 0.03318
KRTAP3-1 keratin associated protein 3-1 0.03318
KRTAP10-7 keratin associated protein 10-7 0.03318
KRTAP10-6 keratin associated protein 10-6 0.03318
KRTAP10-3 keratin associated protein 10-3 0.03318
PADI6 peptidyl arginine deiminase, type VI 0.03318
KRTAP9-8 keratin associated protein 9-8 0.03318
KRTAP9-9 keratin associated protein 9-9 0.03318
KRTAP12-4 keratin associated protein 12-4 0.03318
KRTAP5-4 keratin associated protein 5-4 0.03318
KRTAP5-5 keratin associated protein 5-5 0.03318
KRTAP5-6 keratin associated protein 5-6 0.03318
KRTAP5-7 keratin associated protein 5-7 0.03318
KRTAP5-1 keratin associated protein 5-1 0.03318
KRTAP5-2 keratin associated protein 5-2 0.03318
KRTAP5-3 keratin associated protein 5-3 0.03318
KRTAP5-8 keratin associated protein 5-8 0.03318
KRTAP16-1 keratin associated protein 16-1 0.03318
KRT75 keratin 75, type II 0.03318
KRT74 keratin 74, type II 0.03318
KRT77 keratin 77, type II 0.03318
KRT73 keratin 73, type II 0.03318
KRTAP12-2 keratin associated protein 12-2 0.03318
KRTAP12-3 keratin associated protein 12-3 0.03318
KRTAP12-1 keratin associated protein 12-1 0.03318
KRTAP9-1 keratin associated protein 9-1 0.03318
KRTAP9-2 keratin associated protein 9-2 0.03318
KRTAP9-3 keratin associated protein 9-3 0.03318
KRTAP9-4 keratin associated protein 9-4 0.03318
KRTAP9-6 keratin associated protein 9-6 0.03318
KRTAP9-7 keratin associated protein 9-7 0.03318
KRTAP4-8 keratin associated protein 4-8 0.03318
KRTAP4-1 keratin associated protein 4-1 0.03318
KRTAP4-3 keratin associated protein 4-3 0.03318
KRTAP4-2 keratin associated protein 4-2 0.03318
KRTAP4-5 keratin associated protein 4-5 0.03318
KRTAP4-4 keratin associated protein 4-4 0.03318
KRTAP4-7 keratin associated protein 4-7 0.03318
KRTAP4-6 keratin associated protein 4-6 0.03318
KRT72 keratin 72, type II 0.03318