integrator complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II. (Gene Ontology, GO_0032039)
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Genes

162 proteins co-occuring with the integrator complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
INTS6 integrator complex subunit 6 1.17568
RPAP2 RNA polymerase II associated protein 2 1.00991
INTS7 integrator complex subunit 7 0.994162
CREBBP CREB binding protein 0.984393
INTS12 integrator complex subunit 12 0.971297
INTS1 integrator complex subunit 1 0.953528
HIPK4 homeodomain interacting protein kinase 4 0.930774
INTS4 integrator complex subunit 4 0.926543
CITED4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 0.863068
MIR192 microRNA 192 0.85388
CPSF3L cleavage and polyadenylation specific factor 3-like 0.83322
INTS3 integrator complex subunit 3 0.808441
INTS5 integrator complex subunit 5 0.802938
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.790564
INIP INTS3 and NABP interacting protein 0.785529
SLC39A3 solute carrier family 39 (zinc transporter), member 3 0.765438
IL19 interleukin 19 0.719015
TRIP4 thyroid hormone receptor interactor 4 0.716791
SESTD1 SEC14 and spectrin domains 1 0.703507
NCOA1 nuclear receptor coactivator 1 0.678978
INTS9 integrator complex subunit 9 0.652159
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.634586
TRPA1 transient receptor potential cation channel, subfamily A, member 1 0.629892
SLC6A16 solute carrier family 6, member 16 0.612895
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 0.602752
RANBP10 RAN binding protein 10 0.59896
WNK3 WNK lysine deficient protein kinase 3 0.593072
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 0.580086
SLC39A1 solute carrier family 39 (zinc transporter), member 1 0.575495
STK16 serine/threonine kinase 16 0.568832
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 0.565923
LHX9 LIM homeobox 9 0.560114
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 0.559285
FOXE3 forkhead box E3 0.558457
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.542764
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 0.535361
OSBP2 oxysterol binding protein 2 0.533309
TRPV2 transient receptor potential cation channel, subfamily V, member 2 0.527979
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 0.523067
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 0.520615
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 0.509197
RGS9BP regulator of G protein signaling 9 binding protein 0.504318
OSBPL8 oxysterol binding protein-like 8 0.503506
GSTK1 glutathione S-transferase kappa 1 0.503099
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 0.502288
GPBAR1 G protein-coupled bile acid receptor 1 0.50107
GJB5 gap junction protein, beta 5, 31.1kDa 0.498636
JAG2 jagged 2 0.498231
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5 0.497826
CCAR2 cell cycle and apoptosis regulator 2 0.497826
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 0.496205
OSBPL3 oxysterol binding protein-like 3 0.495395
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.49499
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.492561
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.490539
IKZF3 IKAROS family zinc finger 3 (Aiolos) 0.490539
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 0.488923
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 0.477636
PCP2 Purkinje cell protein 2 0.477636
HIPK1 homeodomain interacting protein kinase 1 0.471609
NPW neuropeptide W 0.468401
NABP2 nucleic acid binding protein 2 0.460001
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 0.458006
VIP vasoactive intestinal peptide 0.454418
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa 0.45004
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 0.446465
G6PC2 glucose-6-phosphatase, catalytic, 2 0.427891
RANBP9 RAN binding protein 9 0.422389
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 0.421212
MIR21 microRNA 21 0.41886
ADORA2B adenosine A2b receptor 0.415728
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.409479
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 0.406361
G6PC3 glucose 6 phosphatase, catalytic, 3 0.401693
PYCR1 pyrroline-5-carboxylate reductase 1 0.399751
TRAPPC10 trafficking protein particle complex 10 0.389682
HIPK3 homeodomain interacting protein kinase 3 0.389682
TUBG1 tubulin, gamma 1 0.387751
RGS7BP regulator of G-protein signaling 7 binding protein 0.386979
TPSG1 tryptase gamma 1 0.377738
SFTPA2 surfactant protein A2 0.372749
SMAD5 SMAD family member 5 0.372366
TADA3 transcriptional adaptor 3 0.371599
ZFP36 ZFP36 ring finger protein 0.367771
CLCNKB chloride channel, voltage-sensitive Kb 0.362804
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 0.35899
LHX2 LIM homeobox 2 0.355563
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.352142
RBBP9 retinoblastoma binding protein 9 0.349863
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 0.348346
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 0.347967
ANKK1 ankyrin repeat and kinase domain containing 1 0.345314
MAF1 MAF1 homolog (S. cerevisiae) 0.342664
DICER1 dicer 1, ribonuclease type III 0.33511
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 0.333602
FOXO1 forkhead box O1 0.328708
SHD Src homology 2 domain containing transforming protein D 0.324951
CYTH2 cytohesin 2 0.321575
GAS1 growth arrest-specific 1 0.320826
CRH corticotropin releasing hormone 0.318953
NPY neuropeptide Y 0.317456
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.316334
CDX1 caudal type homeobox 1 0.294378
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.289569
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.286245
TRPM3 transient receptor potential cation channel, subfamily M, member 3 0.281085
GNB5 guanine nucleotide binding protein (G protein), beta 5 0.279245
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.274101
WNK4 WNK lysine deficient protein kinase 4 0.271533
BIK BCL2-interacting killer (apoptosis-inducing) 0.2708
TRPM8 transient receptor potential cation channel, subfamily M, member 8 0.262755
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 0.260202
TP53 tumor protein p53 0.256925
TBP TATA box binding protein 0.256197
XPO5 exportin 5 0.255834
CCNH cyclin H 0.255107
DRD2 dopamine receptor D2 0.252927
CCNC cyclin C 0.251839
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.250026
PIF1 PIF1 5'-to-3' DNA helicase 0.24894
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 0.24713
SMAD9 SMAD family member 9 0.246407
LMX1B LIM homeobox transcription factor 1, beta 0.245685
FOS FBJ murine osteosarcoma viral oncogene homolog 0.245685
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.243879
CCR2 chemokine (C-C motif) receptor 2 0.243879
GHRL ghrelin/obestatin prepropeptide 0.232744
VAV1 vav 1 guanine nucleotide exchange factor 0.232744
INS insulin 0.231315
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.230958
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.229888
IL31RA interleukin 31 receptor A 0.229532
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 0.222083
CDC73 cell division cycle 73 0.215412
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.214714
HCRTR2 hypocretin (orexin) receptor 2 0.214366
WAS Wiskott-Aldrich syndrome 0.213322
APOLD1 apolipoprotein L domain containing 1 0.21228
GRPR gastrin-releasing peptide receptor 0.210894
SFTPA1 surfactant protein A1 0.209858
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.208137
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.206766
KAT2B K(lysine) acetyltransferase 2B 0.19733
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.192746
FGF21 fibroblast growth factor 21 0.18702
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 0.181524
SMAD7 SMAD family member 7 0.177724
CARM1 coactivator-associated arginine methyltransferase 1 0.175188
TAZ tafazzin 0.173273
LPO lactoperoxidase 0.172735
RARS arginyl-tRNA synthetase 0.172468
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 0.171937
BCL2L1 BCL2-like 1 0.17141
CDK8 cyclin-dependent kinase 8 0.167366
CLINT1 clathrin interactor 1 0.162546
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 0.16233
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 0.161275
FLNB filamin B, beta 0.160456
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.157943
TAL1 T-cell acute lymphocytic leukemia 1 0.156688
JUN jun proto-oncogene 0.156688
PPARG peroxisome proliferator-activated receptor gamma 0.156513