inner nuclear layer Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The layer of the retina composed of the cell bodies of bipolar cells, horizontal cells, and some of the cell bodies of amacrine cells. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003176)
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Genes

302 proteins co-occuring with the tissue inner nuclear layer in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
VSX2 visual system homeobox 2 1.88529
RCVRN recoverin 1.81634
TH tyrosine hydroxylase 1.81277
RHO rhodopsin 1.67356
CHAT choline O-acetyltransferase 1.63906
OPN4 opsin 4 1.46635
PVALB parvalbumin 1.4575
CALB1 calbindin 1, 28kDa 1.43246
CALB2 calbindin 2 1.4163
VSX1 visual system homeobox 1 1.41583
PAX6 paired box 6 1.38825
CERKL ceramide kinase-like 1.23539
TRPM1 transient receptor potential cation channel, subfamily M, member 1 1.21268
ZNF513 zinc finger protein 513 1.198
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 1.18157
RLBP1 retinaldehyde binding protein 1 1.17181
CRX cone-rod homeobox 1.15717
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.11509
ISL1 ISL LIM homeobox 1 1.11287
DNTT DNA nucleotidylexotransferase 1.1111
ARR3 arrestin 3, retinal (X-arrestin) 1.08722
PCNA proliferating cell nuclear antigen 1.06206
NR2E3 nuclear receptor subfamily 2, group E, member 3 1.05501
MNX1 motor neuron and pancreas homeobox 1 1.05457
GJD2 gap junction protein, delta 2, 36kDa 1.05413
PNMT phenylethanolamine N-methyltransferase 1.04796
RAX retina and anterior neural fold homeobox 1.04445
POU4F1 POU class 4 homeobox 1 1.04313
BDNF brain-derived neurotrophic factor 1.04093
SST somatostatin 1.04005
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 1.00458
NUMBL numb homolog (Drosophila)-like 0.999344
CNTF ciliary neurotrophic factor 0.993249
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 0.988032
TAC1 tachykinin, precursor 1 0.981084
CRY2 cryptochrome circadian clock 2 0.975449
GATAD1 GATA zinc finger domain containing 1 0.971984
NRL neural retina leucine zipper 0.96809
GRM6 glutamate receptor, metabotropic 6 0.95729
RAB11FIP4 RAB11 family interacting protein 4 (class II) 0.929335
FABP12 fatty acid binding protein 12 0.926764
NPY neuropeptide Y 0.925051
CTBP2 C-terminal binding protein 2 0.904127
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.904127
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 0.889253
PROX1 prospero homeobox 1 0.872749
OPN5 opsin 5 0.858837
NGB neuroglobin 0.858416
GLUL glutamate-ammonia ligase 0.849585
CCNDBP1 cyclin D-type binding-protein 1 0.840349
RIT2 Ras-like without CAAX 2 0.823594
ISLR immunoglobulin superfamily containing leucine-rich repeat 0.808968
GRM4 glutamate receptor, metabotropic 4 0.801459
MYO3B myosin IIIB 0.799375
FGF2 fibroblast growth factor 2 (basic) 0.798958
RBP3 retinol binding protein 3, interstitial 0.783141
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.779816
FOS FBJ murine osteosarcoma viral oncogene homolog 0.75495
FIZ1 FLT3-interacting zinc finger 1 0.75371
PNMA2 paraneoplastic Ma antigen 2 0.752884
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.751231
NEUROD4 neuronal differentiation 4 0.745864
NYX nyctalopin 0.745039
TULP3 tubby like protein 3 0.74174
GPR179 G protein-coupled receptor 179 0.73803
RAX2 retina and anterior neural fold homeobox 2 0.735147
PRDM8 PR domain containing 8 0.729385
IMPG2 interphotoreceptor matrix proteoglycan 2 0.711319
RASGEF1B RasGEF domain family, member 1B 0.7105
RABGAP1 RAB GTPase activating protein 1 0.705993
AQP4 aquaporin 4 0.700262
ASMT acetylserotonin O-methyltransferase 0.690042
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.683919
GFAP glial fibrillary acidic protein 0.683103
CDH8 cadherin 8, type 2 0.67984
CAMK4 calcium/calmodulin-dependent protein kinase IV 0.676172
CDH7 cadherin 7, type 2 0.672506
CDH4 cadherin 4, type 1, R-cadherin (retinal) 0.668436
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.665588
NADSYN1 NAD synthetase 1 0.659491
ACAD9 acyl-CoA dehydrogenase family, member 9 0.65746
POU4F2 POU class 4 homeobox 2 0.6534
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 0.65056
CDH20 cadherin 20, type 2 0.65056
GRIA4 glutamate receptor, ionotropic, AMPA 4 0.646505
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.643669
CDH19 cadherin 19, type 2 0.63719
ARL6 ADP-ribosylation factor-like 6 0.626273
CNTFR ciliary neurotrophic factor receptor 0.624658
OPN1LW opsin 1 (cone pigments), long-wave-sensitive 0.6182
OPN1MW2 opsin 1 (cone pigments), medium-wave-sensitive 2 0.61699
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.616586
JUN jun proto-oncogene 0.613361
CABP5 calcium binding protein 5 0.612958
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 0.612555
HFE2 hemochromatosis type 2 (juvenile) 0.609332
OPN1MW opsin 1 (cone pigments), medium-wave-sensitive 0.606916
RPE65 retinal pigment epithelium-specific protein 65kDa 0.605306
PADI2 peptidyl arginine deiminase, type II 0.601283
CRY1 cryptochrome circadian clock 1 0.599273
NMNAT3 nicotinamide nucleotide adenylyltransferase 3 0.599273
STX1A syntaxin 1A (brain) 0.597666
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.590437
BEST1 bestrophin 1 0.587228
FGF1 fibroblast growth factor 1 (acidic) 0.579617
PCDH18 protocadherin 18 0.578816
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.570021
SLC30A7 solute carrier family 30 (zinc transporter), member 7 0.566428
RRH retinal pigment epithelium-derived rhodopsin homolog 0.563238
SIX3 SIX homeobox 3 0.558457
BARHL2 BarH-like homeobox 2 0.556865
VEGFA vascular endothelial growth factor A 0.556865
CLRN1 clarin 1 0.554478
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1 0.549312
C11ORF40 chromosome 11 open reading frame 40 0.547326
CRYBA1 crystallin, beta A1 0.541377
TSPO translocator protein (18kDa) 0.540585
BSN bassoon presynaptic cytomatrix protein 0.537416
SYP synaptophysin 0.537021
FGFR1 fibroblast growth factor receptor 1 0.53346
ATOH7 atonal homolog 7 (Drosophila) 0.53267
NTF4 neurotrophin 4 0.529508
BHLHE22 basic helix-loop-helix family, member e22 0.52635
PRPF31 pre-mRNA processing factor 31 0.525166
BHLHE23 basic helix-loop-helix family, member e23 0.524377
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 0.523588
NEUROD1 neuronal differentiation 1 0.5228
PTBP3 polypyrimidine tract binding protein 3 0.522011
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 0.519253
AANAT aralkylamine N-acetyltransferase 0.512564
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.510599
WDR92 WD repeat domain 92 0.50471
OLFM1 olfactomedin 1 0.50275
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.500007
LIN7C lin-7 homolog C (C. elegans) 0.49844
EDA ectodysplasin A 0.495701
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.492963
LECT1 leukocyte cell derived chemotaxin 1 0.490619
MYO3A myosin IIIA 0.490229
KIF14 kinesin family member 14 0.485935
RAI14 retinoic acid induced 14 0.478923
GLB1 galactosidase, beta 1 0.478145
FLT1 fms-related tyrosine kinase 1 0.478145
RBPMS RNA binding protein with multiple splicing 0.475034
ACHE acetylcholinesterase (Yt blood group) 0.47348
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 0.471151
NTF3 neurotrophin 3 0.470375
NTS neurotensin 0.468824
RGR retinal G protein coupled receptor 0.465723
GRIK1 glutamate receptor, ionotropic, kainate 1 0.460692
OLIG2 oligodendrocyte lineage transcription factor 2 0.458373
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.454512
GDF5 growth differentiation factor 5 0.454512
GPHN gephyrin 0.451813
CSAD cysteine sulfinic acid decarboxylase 0.449116
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.448731
CPT1C carnitine palmitoyltransferase 1C 0.447961
SIGMAR1 sigma non-opioid intracellular receptor 1 0.446422
TULP1 tubby like protein 1 0.442962
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.440658
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 0.440274
NES nestin 0.43414
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.433374
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.430312
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 0.42993
PRKG1 protein kinase, cGMP-dependent, type I 0.428018
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 0.427636
SLC30A10 solute carrier family 30, member 10 0.426872
PCDH17 protocadherin 17 0.424199
ISL2 ISL LIM homeobox 2 0.424199
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5 0.423054
GUCY2C guanylate cyclase 2C 0.421529
NPR1 natriuretic peptide receptor 1 0.419242
PCDH7 protocadherin 7 0.415053
ABAT 4-aminobutyrate aminotransferase 0.413912
ELAVL3 ELAV like neuron-specific RNA binding protein 3 0.413912
PCDH9 protocadherin 9 0.413151
LHX2 LIM homeobox 2 0.406315
ARTN artemin 0.402144
GFRA2 GDNF family receptor alpha 2 0.401765
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.400628
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 0.400628
CA2 carbonic anhydrase II 0.396087
OTX2 orthodenticle homeobox 2 0.394953
MAP2 microtubule-associated protein 2 0.389289
VIP vasoactive intestinal peptide 0.388912
NPS neuropeptide S 0.388535
PER1 period circadian clock 1 0.387781
TFR2 transferrin receptor 2 0.386273
SDF4 stromal cell derived factor 4 0.382131
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.379499
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) 0.379123
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8 0.378748
BSX brain-specific homeobox 0.377621
TRPV2 transient receptor potential cation channel, subfamily V, member 2 0.375743
CAST calpastatin 0.37087
CDK5 cyclin-dependent kinase 5 0.370496
KDR kinase insert domain receptor 0.368998
SACS sacsin molecular chaperone 0.368998
GRM7 glutamate receptor, metabotropic 7 0.366754
THY1 Thy-1 cell surface antigen 0.362646
PDC phosducin 0.362273
SYNPR synaptoporin 0.361901
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 0.358174
BBS4 Bardet-Biedl syndrome 4 0.356686
PRPH2 peripherin 2 (retinal degeneration, slow) 0.356314
TXN thioredoxin 0.354826
OPA1 optic atrophy 1 (autosomal dominant) 0.354826
PCDH1 protocadherin 1 0.354455
LHX3 LIM homeobox 3 0.352969
MAPK13 mitogen-activated protein kinase 13 0.352598
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.350743
GJB5 gap junction protein, beta 5, 31.1kDa 0.34926
CABP1 calcium binding protein 1 0.347778
EDN2 endothelin 2 0.342602
NGF nerve growth factor (beta polypeptide) 0.341863
SOD2 superoxide dismutase 2, mitochondrial 0.338545
PLCH2 phospholipase C, eta 2 0.337808
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.33744
PCLO piccolo presynaptic cytomatrix protein 0.33744
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 0.336336
CARD17 caspase recruitment domain family, member 17 0.3356
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 0.333763
ASCL1 achaete-scute family bHLH transcription factor 1 0.332294
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1 0.329361
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.322414
GRM2 glutamate receptor, metabotropic 2 0.32205
TXNIP thioredoxin interacting protein 0.32132
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 0.319498
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.312957
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.309335
TBX5 T-box 5 0.308974
SAG S-antigen; retina and pineal gland (arrestin) 0.307167
OCLN occludin 0.306083
IRX6 iroquois homeobox 6 0.305001
ADAM23 ADAM metallopeptidase domain 23 0.30464
MFRP membrane frizzled-related protein 0.30032
EDN1 endothelin 1 0.297806
LIN7A lin-7 homolog A (C. elegans) 0.295655
IGFBP6 insulin-like growth factor binding protein 6 0.295297
CREB1 cAMP responsive element binding protein 1 0.294223
PDE1B phosphodiesterase 1B, calmodulin-dependent 0.291722
RS1 retinoschisin 1 0.290295
PCDH10 protocadherin 10 0.287803
SRPX2 sushi-repeat containing protein, X-linked 2 0.287803
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.287447
AQP6 aquaporin 6, kidney specific 0.286381
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 0.286026
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 0.285316
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.283191
RIPK3 receptor-interacting serine-threonine kinase 3 0.28107
RD3 retinal degeneration 3 0.275794
SYN1 synapsin I 0.275444
TRNAU1AP tRNA selenocysteine 1 associated protein 1 0.275094
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.274394
KLF15 Kruppel-like factor 15 0.272649
BAX BCL2-associated X protein 0.2723
RELN reelin 0.270909
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 0.269867
RND1 Rho family GTPase 1 0.269174
NOS3 nitric oxide synthase 3 (endothelial cell) 0.267102
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.260606
GCG glucagon 0.260267
IL27 interleukin 27 0.25858
PENK proenkephalin 0.256568
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 0.256568
LHX9 LIM homeobox 9 0.254239
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.25259
PLIN2 perilipin 2 0.251606
CERK ceramide kinase 0.251279
CNGA3 cyclic nucleotide gated channel alpha 3 0.249329
NRTN neurturin 0.243605
MGEA5 meningioma expressed antigen 5 (hyaluronidase) 0.241132
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 0.240216
MAPK8 mitogen-activated protein kinase 8 0.239307
KDM6B lysine (K)-specific demethylase 6B 0.238108
SCRT1 scratch family zinc finger 1 0.237513
TSPAN7 tetraspanin 7 0.237216
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.237216
FGFR4 fibroblast growth factor receptor 4 0.235748
SYT2 synaptotagmin II 0.235748
CCND1 cyclin D1 0.235748
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.235748
PTBP2 polypyrimidine tract binding protein 2 0.234016
GJA8 gap junction protein, alpha 8, 50kDa 0.234016
ATF6 activating transcription factor 6 0.232599
AACS acetoacetyl-CoA synthetase 0.230931
CNTN2 contactin 2 (axonal) 0.228497
GJC1 gap junction protein, gamma 1, 45kDa 0.22797
SLC30A8 solute carrier family 30 (zinc transporter), member 8 0.226926
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.22415
FABP9 fatty acid binding protein 9, testis 0.223662
ADAM22 ADAM metallopeptidase domain 22 0.222938
CYR61 cysteine-rich, angiogenic inducer, 61 0.22246
TXN2 thioredoxin 2 0.220604
GRM1 glutamate receptor, metabotropic 1 0.219485
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.216325
SCN3A sodium channel, voltage gated, type III alpha subunit 0.215147
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.213291
PPT1 palmitoyl-protein thioesterase 1 0.212936
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.212586
LHX1 LIM homeobox 1 0.212586