inner cell mass degeneration Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description a retrogressive impairment of function or destruction of the cells of the blastocyst that develop into the body of the embryo (Mammalian Phenotype Ontology, MP_0004965)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004965
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Genes

32 gene mutations causing the inner cell mass degeneration phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AURKA aurora kinase A
BARD1 BRCA1 associated RING domain 1
BIRC5 baculoviral IAP repeat containing 5
BRD4 bromodomain containing 4
BUB3 BUB3 mitotic checkpoint protein
CDC7 cell division cycle 7
CENPA centromere protein A
CHD8 chromodomain helicase DNA binding protein 8
COPS5 COP9 signalosome subunit 5
DMBT1 deleted in malignant brain tumors 1
FEN1 flap structure-specific endonuclease 1
FGFR2 fibroblast growth factor receptor 2
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
LIN9 lin-9 DREAM MuvB core complex component
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MBTPS1 membrane-bound transcription factor peptidase, site 1
MIS18A MIS18 kinetochore protein A
MNAT1 MNAT CDK-activating kinase assembly factor 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NBN nibrin
NDEL1 nudE neurodevelopment protein 1-like 1
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
PPP4C protein phosphatase 4, catalytic subunit
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAE1 ribonucleic acid export 1
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SSB Sjogren syndrome antigen B (autoantigen La)
SSRP1 structure specific recognition protein 1
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
ZNF24 zinc finger protein 24