index Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Similar Terms
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Genes

465 genes co-occuring with the biological term index in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ACAD9 acyl-CoA dehydrogenase family, member 9
ACE angiotensin I converting enzyme
ACSM3 acyl-CoA synthetase medium-chain family member 3
ADA adenosine deaminase
ADD1 adducin 1 (alpha)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRA2A adrenoceptor alpha 2A
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AFP alpha-fetoprotein
AGER advanced glycosylation end product-specific receptor
AGRP agouti related neuropeptide
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AHI1 Abelson helper integration site 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALG11 ALG11, alpha-1,2-mannosyltransferase
AMELX amelogenin, X-linked
AMELY amelogenin, Y-linked
AMH anti-Mullerian hormone
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANKH ANKH inorganic pyrophosphate transport regulator
ANKK1 ankyrin repeat and kinase domain containing 1
ANPEP alanyl (membrane) aminopeptidase
ANXA2 annexin A2
APC adenomatous polyposis coli
APOA1 apolipoprotein A-I
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOC1 apolipoprotein C-I
APOE apolipoprotein E
ARMS2 age-related maculopathy susceptibility 2
ATF6 activating transcription factor 6
ATM ATM serine/threonine kinase
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
AVPR1A arginine vasopressin receptor 1A
B2M beta-2-microglobulin
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL6 B-cell CLL/lymphoma 6
BDNF brain-derived neurotrophic factor
BGLAP bone gamma-carboxyglutamate (gla) protein
BID BH3 interacting domain death agonist
BIRC5 baculoviral IAP repeat containing 5
BMP4 bone morphogenetic protein 4
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRAP BRCA1 associated protein
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
C4A complement component 4A (Rodgers blood group)
C4B complement component 4B (Chido blood group)
C4ORF32 chromosome 4 open reading frame 32
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CALCA calcitonin-related polypeptide alpha
CAPN10 calpain 10
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CAV3 caveolin 3
CCNA2 cyclin A2
CCNB1 cyclin B1
CCND1 cyclin D1
CCNE1 cyclin E1
CCR2 chemokine (C-C motif) receptor 2
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD163 CD163 molecule
CD24 CD24 molecule
CD27 CD27 molecule
CD34 CD34 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD99 CD99 molecule
CDK4 cyclin-dependent kinase 4
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2B-AS1 CDKN2B antisense RNA 1
CDX2 caudal type homeobox 2
CFH complement factor H
CGB5 chorionic gonadotropin, beta polypeptide 5
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIT1 chitinase 1 (chitotriosidase)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CKAP2 cytoskeleton associated protein 2
CKS2 CDC28 protein kinase regulatory subunit 2
CLCN1 chloride channel, voltage-sensitive 1
CLU clusterin
CNOT3 CCR4-NOT transcription complex, subunit 3
CNR1 cannabinoid receptor 1 (brain)
COX2
CREBBP CREB binding protein
CRP C-reactive protein, pentraxin-related
CSF1 colony stimulating factor 1 (macrophage)
CST3 cystatin C
CTSL cathepsin L
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR6 chemokine (C-X-C motif) receptor 6
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A cytochrome P450, family 3, subfamily A
DAPK1 death-associated protein kinase 1
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DGAT1 diacylglycerol O-acyltransferase 1
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
DSG3 desmoglein 3
DSP desmoplakin
E2F1 E2F transcription factor 1
EBAG9 estrogen receptor binding site associated, antigen, 9
EDN1 endothelin 1
EGFR epidermal growth factor receptor
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC2 excision repair cross-complementation group 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EXT1 exostosin glycosyltransferase 1
EXT2 exostosin glycosyltransferase 2
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAAH fatty acid amide hydrolase
FABP2 fatty acid binding protein 2, intestinal
FABP4 fatty acid binding protein 4, adipocyte
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBXO32 F-box protein 32
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FFAR3 free fatty acid receptor 3
FFAR4 free fatty acid receptor 4
FGF21 fibroblast growth factor 21
FGF23 fibroblast growth factor 23
FGL2 fibrinogen-like 2
FHL1 four and a half LIM domains 1
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLT1 fms-related tyrosine kinase 1
FMR1 fragile X mental retardation 1
FNDC5 fibronectin type III domain containing 5
FOSL1 FOS-like antigen 1
FOXA2 forkhead box A2
FOXP3 forkhead box P3
FSCN1 fascin actin-bundling protein 1
FTO fat mass and obesity associated
FUS FUS RNA binding protein
FXN frataxin
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GCH1 GTP cyclohydrolase 1
GCK glucokinase (hexokinase 4)
GCKR glucokinase (hexokinase 4) regulator
GDNF glial cell derived neurotrophic factor
GGT1 gamma-glutamyltransferase 1
GGT2 gamma-glutamyltransferase 2
GH1 growth hormone 1
GH2 growth hormone 2
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GIPR gastric inhibitory polypeptide receptor
GJB2 gap junction protein, beta 2, 26kDa
GJB6 gap junction protein, beta 6, 30kDa
GLRA1 glycine receptor, alpha 1
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HBA1 hemoglobin, alpha 1
HBG2 hemoglobin, gamma G
HCRT hypocretin (orexin) neuropeptide precursor
HESX1 HESX homeobox 1
HHEX hematopoietically expressed homeobox
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIPK2 homeodomain interacting protein kinase 2
HIST3H3 histone cluster 3, H3
HLA-B major histocompatibility complex, class I, B
HMGA1 high mobility group AT-hook 1
HMMR hyaluronan-mediated motility receptor (RHAMM)
HNF1A HNF1 homeobox A
HOXB13 homeobox B13
HP haptoglobin
HR hair growth associated
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSPA4 heat shock 70kDa protein 4
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IDE insulin-degrading enzyme
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGFBP3 insulin-like growth factor binding protein 3
IL12B interleukin 12B
IL16 interleukin 16
IL17A interleukin 17A
IL17RB interleukin 17 receptor B
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RL1 interleukin 1 receptor-like 1
IL1RN interleukin 1 receptor antagonist
IL23A interleukin 23, alpha subunit p19
IL33 interleukin 33
IL5 interleukin 5
IL6 interleukin 6
IL6R interleukin 6 receptor
INS insulin
INSIG2 insulin induced gene 2
IRS4 insulin receptor substrate 4
ITGAV integrin, alpha V
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITLN1 intelectin 1 (galactofuranose binding)
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLK3 kallikrein-related peptidase 3
KRT19 keratin 19, type I
LBR lamin B receptor
LDHA lactate dehydrogenase A
LDHB lactate dehydrogenase B
LEP leptin
LEPQTL1 Leptin, serum levels of
LEPR leptin receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LIPC lipase, hepatic
LPL lipoprotein lipase
LRP1 low density lipoprotein receptor-related protein 1
LRP1B low density lipoprotein receptor-related protein 1B
MAOA monoamine oxidase A
MBP myelin basic protein
MC3R melanocortin 3 receptor
MC4R melanocortin 4 receptor
MCM2 minichromosome maintenance complex component 2
MCM6 minichromosome maintenance complex component 6
MEN1 multiple endocrine neoplasia I
MGP matrix Gla protein
MIR122 microRNA 122
MIR125B1 microRNA 125b-1
MIR221 microRNA 221
MIR325 microRNA 325
MIRLET7I microRNA let-7i
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MNX1 motor neuron and pancreas homeobox 1
MPO myeloperoxidase
MPZ myelin protein zero
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MSTN myostatin
MTCH2 mitochondrial carrier 2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC16 mucin 16, cell surface associated
MUC7 mucin 7, secreted
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAMPT nicotinamide phosphoribosyltransferase
NANOG Nanog homeobox
NCOA3 nuclear receptor coactivator 3
NEUROG3 neurogenin 3
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH3 notch 3
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NPY neuropeptide Y
NPY2R neuropeptide Y receptor Y2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRXN3 neurexin 3
NTN1 netrin 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUCB2 nucleobindin 2
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
OCA2 oculocutaneous albinism II
OLIG1 oligodendrocyte transcription factor 1
OLIG2 oligodendrocyte lineage transcription factor 2
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PAH phenylalanine hydroxylase
PANK2 pantothenate kinase 2
PAX2 paired box 2
PCDH12 protocadherin 12
PCSK1 proprotein convertase subtilisin/kexin type 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDYN prodynorphin
PEPD peptidase D
PGF placental growth factor
PGR progesterone receptor
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKP1 plakophilin 1
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAGL1 pleiomorphic adenoma gene-like 1
PMCH pro-melanin-concentrating hormone
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PNPLA2 patatin-like phospholipase domain containing 2
PNPLA3 patatin-like phospholipase domain containing 3
PNPLA6 patatin-like phospholipase domain containing 6
PON1 paraoxonase 1
POU5F1 POU class 5 homeobox 1
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRDM16 PR domain containing 16
PRL prolactin
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROM1 prominin 1
PTGES2 prostaglandin E synthase 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTPRR protein tyrosine phosphatase, receptor type, R
PTTG1 pituitary tumor-transforming 1
QPCTL glutaminyl-peptide cyclotransferase-like
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RBP4 retinol binding protein 4, plasma
RETN resistin
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RNLS renalase, FAD-dependent amine oxidase
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPL21P7 ribosomal protein L21 pseudogene 7
RYR1 ryanodine receptor 1 (skeletal)
S100A1 S100 calcium binding protein A1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
SACS sacsin molecular chaperone
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB2A2 secretoglobin, family 2A, member 2
SCLT1 sodium channel and clathrin linker 1
SDC1 syndecan 1
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP5 secreted frizzled-related protein 5
SHBG sex hormone-binding globulin
SHH sonic hedgehog
SIM1 single-minded family bHLH transcription factor 1
SIRT1 sirtuin 1
SIX3 SIX homeobox 3
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC45A2 solute carrier family 45, member 2
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SNCB synuclein, beta
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SORBS1 sorbin and SH3 domain containing 1
SOX1 SRY (sex determining region Y)-box 1
SPP1 secreted phosphoprotein 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D22A TBC1 domain family, member 22A
TBC1D32 TBC1 domain family, member 32
TCF4 transcription factor 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TEK TEK tyrosine kinase, endothelial
TERT telomerase reverse transcriptase
TET2 tet methylcytosine dioxygenase 2
TF transferrin
TGFB1 transforming growth factor, beta 1
TGM1 transglutaminase 1
THADA thyroid adenoma associated
THPO thrombopoietin
THRB thyroid hormone receptor, beta
TIMP2 TIMP metallopeptidase inhibitor 2
TK1 thymidine kinase 1, soluble
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TLX3 T-cell leukemia homeobox 3
TMEM18 transmembrane protein 18
TMPRSS2 transmembrane protease, serine 2
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP2B topoisomerase (DNA) II beta 180kDa
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TPSAB1 tryptase alpha/beta 1
TREM1 triggering receptor expressed on myeloid cells 1
TRIB2 tribbles pseudokinase 2
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase
TSC2 tuberous sclerosis 2
TTR transthyretin
TYMP thymidine phosphorylase
TYR tyrosinase
UBE2C ubiquitin-conjugating enzyme E2C
UBE2N ubiquitin-conjugating enzyme E2N
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UGT8 UDP glycosyltransferase 8
VASP vasodilator-stimulated phosphoprotein
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
VWF von Willebrand factor
WFDC2 WAP four-disulfide core domain 2
WISP1 WNT1 inducible signaling pathway protein 1
WNT3 wingless-type MMTV integration site family, member 3
WRN Werner syndrome, RecQ helicase-like
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZIC2 Zic family member 2