increased urinary system tumor incidence Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than the expected number of tumors originating in the urinary system in a given population in a given time period (Mammalian Phenotype Ontology, MP_0010289)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010289
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Genes

13 gene mutations causing the increased urinary system tumor incidence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AHR aryl hydrocarbon receptor
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
DKC1 dyskeratosis congenita 1, dyskerin
FLCN folliculin
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
NF2 neurofibromin 2 (merlin)
PKD1 polycystic kidney disease 1 (autosomal dominant)
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
SPTBN1 spectrin, beta, non-erythrocytic 1
TP53 tumor protein p53
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2