increased transitional stage b cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater number of immature B cells of an intermediate stage between the pre-B cell stage and the mature naive stage; transitional B cells express surface immunoglobulin, and are subject to the process of B cell selection (Mammalian Phenotype Ontology, MP_0008189)
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19 gene mutations causing the increased transitional stage b cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AKAP13 A kinase (PRKA) anchor protein 13
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BMF Bcl2 modifying factor
CD36 CD36 molecule (thrombospondin receptor)
CD79A CD79a molecule, immunoglobulin-associated alpha
DLK1 delta-like 1 homolog (Drosophila)
EPS15 epidermal growth factor receptor pathway substrate 15
FAS Fas cell surface death receptor
FLI1 Fli-1 proto-oncogene, ETS transcription factor
IRF8 interferon regulatory factor 8
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PRKCD protein kinase C, delta
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRAF3IP2 TRAF3 interacting protein 2
VAV1 vav 1 guanine nucleotide exchange factor