increased total body fat amount Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than the normal total amount of connective tissue composed of fat cells within the entire body (Mammalian Phenotype Ontology, MP_0010024)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010024
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Genes

92 gene mutations causing the increased total body fat amount phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRB3 adrenoceptor beta 3
ADRM1 adhesion regulating molecule 1
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALMS1 Alstrom syndrome protein 1
ANGPTL6 angiopoietin-like 6
ASIP agouti signaling protein
B9D1 B9 protein domain 1
BBS1 Bardet-Biedl syndrome 1
BBS4 Bardet-Biedl syndrome 4
BBS5 Bardet-Biedl syndrome 5
BGLAP bone gamma-carboxyglutamate (gla) protein
BRD2 bromodomain containing 2
CARTPT CART prepropeptide
CCDC80 coiled-coil domain containing 80
CCL25 chemokine (C-C motif) ligand 25
CDH23 cadherin-related 23
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEP19 centrosomal protein 19kDa
CPE carboxypeptidase E
CRH corticotropin releasing hormone
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTF1 cardiotrophin 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DKC1 dyskeratosis congenita 1, dyskerin
DMXL2 Dmx-like 2
DPT dermatopontin
DRD3 dopamine receptor D3
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FFAR4 free fatty acid receptor 4
FGF10 fibroblast growth factor 10
FGF21 fibroblast growth factor 21
FTO fat mass and obesity associated
GDF15 growth differentiation factor 15
GHR growth hormone receptor
GHRHR growth hormone releasing hormone receptor
GNAS GNAS complex locus
GPR26 G protein-coupled receptor 26
GUCY2C guanylate cyclase 2C
HRH3 histamine receptor H3
IL1R1 interleukin 1 receptor, type I
IRS2 insulin receptor substrate 2
KMT2B lysine (K)-specific methyltransferase 2B
KPTN kaptin (actin binding protein)
LEP leptin
LEPR leptin receptor
MC3R melanocortin 3 receptor
MC4R melanocortin 4 receptor
MRAP2 melanocortin 2 receptor accessory protein 2
MTA1 metastasis associated 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NCOA3 nuclear receptor coactivator 3
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NMUR2 neuromedin U receptor 2
NPY1R neuropeptide Y receptor Y1
NPY5R neuropeptide Y receptor Y5
NPY6R neuropeptide Y receptor Y6 (pseudogene)
OPRM1 opioid receptor, mu 1
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6
PAM peptidylglycine alpha-amidating monooxygenase
POMC proopiomelanocortin
PPARD peroxisome proliferator-activated receptor delta
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PRDM4 PR domain containing 4
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRLHR prolactin releasing hormone receptor
PROX1 prospero homeobox 1
PYY peptide YY
RGS4 regulator of G-protein signaling 4
RNF10 ring finger protein 10
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPGRIP1L RPGRIP1-like
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SIM1 single-minded family bHLH transcription factor 1
SIRT3 sirtuin 3
SNAP47 synaptosomal-associated protein, 47kDa
SNRPN small nuclear ribonucleoprotein polypeptide N
SPG20 spastic paraplegia 20 (Troyer syndrome)
SYT1 synaptotagmin I
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THRA thyroid hormone receptor, alpha
TLR5 toll-like receptor 5
TOM1L2 target of myb1-like 2 (chicken)
TUB tubby bipartite transcription factor
UBB ubiquitin B
USP38 ubiquitin specific peptidase 38
ZEB1 zinc finger E-box binding homeobox 1