increased testis tumor incidence Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than the expected number of abnormal rapidly proliferating cells in the testis, usually in the form of a distinct mass, occurring in a specific population in a given time period (Mammalian Phenotype Ontology, MP_0006262)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0006262
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Genes

15 gene mutations causing the increased testis tumor incidence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AMHR2 anti-Mullerian hormone receptor, type II
AR androgen receptor
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
DND1 DND microRNA-mediated repression inhibitor 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
INHA inhibin, alpha
KITLG KIT ligand
MEN1 multiple endocrine neoplasia I
NBN nibrin
NR0B1 nuclear receptor subfamily 0, group B, member 1
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
SF1 splicing factor 1
SPTBN1 spectrin, beta, non-erythrocytic 1
TP53 tumor protein p53