increased teratoma incidence Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description higher than normal incidence of generally benign germ cell-derived tumors of male or female containing derivatives from all three germ layers with differentiation in the malignant form being poor; malignant tumors are highly metatstatic (Mammalian Phenotype Ontology, MP_0002627)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002627
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Genes

8 gene mutations causing the increased teratoma incidence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
DCLRE1A DNA cross-link repair 1A
DND1 DND microRNA-mediated repression inhibitor 1
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
KITLG KIT ligand
MOS v-mos Moloney murine sarcoma viral oncogene homolog
PTEN phosphatase and tensin homolog
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
TP53 tumor protein p53