increased t cell apoptosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the number of T cells undergoing programmed cell death (Mammalian Phenotype Ontology, MP_0006413)
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48 gene mutations causing the increased t cell apoptosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
BIRC6 baculoviral IAP repeat containing 6
BRAF B-Raf proto-oncogene, serine/threonine kinase
CD27 CD27 molecule
CD28 CD28 molecule
CD38 CD38 molecule
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CDK6 cyclin-dependent kinase 6
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COPS6 COP9 signalosome subunit 6
CORO1A coronin, actin binding protein, 1A
DCK deoxycytidine kinase
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
FAIM Fas apoptotic inhibitory molecule
FCMR Fc fragment of IgM receptor
FOXP3 forkhead box P3
IL15RA interleukin 15 receptor, alpha
ING1 inhibitor of growth family, member 1
KIFAP3 kinesin-associated protein 3
LECT2 leukocyte cell-derived chemotaxin 2
LIG4 ligase IV, DNA, ATP-dependent
MERTK MER proto-oncogene, tyrosine kinase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NHEJ1 nonhomologous end-joining factor 1
NOTCH1 notch 1
PARL presenilin associated, rhomboid-like
PKNOX1 PBX/knotted 1 homeobox 1
PNP purine nucleoside phosphorylase
PRKCQ protein kinase C, theta
PTPRC protein tyrosine phosphatase, receptor type, C
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RORC RAR-related orphan receptor C
RPL22 ribosomal protein L22
RUNX1 runt-related transcription factor 1
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK4 serine/threonine kinase 4
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TNFRSF18 tumor necrosis factor receptor superfamily, member 18
TP53 tumor protein p53
TP73 tumor protein p73
TPP2 tripeptidyl peptidase II
TRAF2 TNF receptor-associated factor 2
TWSG1 twisted gastrulation BMP signaling modulator 1
USP4 ubiquitin specific peptidase 4 (proto-oncogene)