increased spindle cell carcinoma incidence Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than the expected number of a highly malignant variant of squamous cell carcinoma, occurring in a specific population in a given time period; spindle cell carcinoma shows biphasic proliferation of conventional SCC component and malignant spindle shape cells with sarcomatous appearance (Mammalian Phenotype Ontology, MP_0010367)
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3 gene mutations causing the increased spindle cell carcinoma incidence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ATAD5 ATPase family, AAA domain containing 5
TP53 tumor protein p53
TRIM62 tripartite motif containing 62