increased skeletal tumor incidence Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than the expected number of neoplasms in the skeletal tissue, usually in the form of a distinct mass, in a specific population in a given time period (Mammalian Phenotype Ontology, MP_0010280)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010280
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Genes

12 gene mutations causing the increased skeletal tumor incidence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACVR1 activin A receptor, type I
CDKN2A cyclin-dependent kinase inhibitor 2A
EXT1 exostosin glycosyltransferase 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MSH2 mutS homolog 2
NF2 neurofibromin 2 (merlin)
PRDX1 peroxiredoxin 1
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
SAV1 salvador family WW domain containing protein 1
TP53 tumor protein p53
WIF1 WNT inhibitory factor 1
WWOX WW domain containing oxidoreductase