increased renal tubule apoptosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the number of renal tubule cells undergoing programmed cell death (Mammalian Phenotype Ontology, MP_0004153)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004153
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Genes

11 gene mutations causing the increased renal tubule apoptosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
DCN decorin
GLIS2 GLIS family zinc finger 2
HELLS helicase, lymphoid-specific
HMOX1 heme oxygenase 1
LRRK2 leucine-rich repeat kinase 2
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
NOS3 nitric oxide synthase 3 (endothelial cell)
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TRPV5 transient receptor potential cation channel, subfamily V, member 5