increased regulatory t cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater number of the specialized subpopulation of T cells that act to suppress activation of the immune system and thus maintain immune system homeostasis and prevent pathological self-reactivity (Mammalian Phenotype Ontology, MP_0004973)
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17 gene mutations causing the increased regulatory t cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BCL2L11 BCL2-like 11 (apoptosis facilitator)
CD247 CD247 molecule
CD5 CD5 molecule
CTSV cathepsin V
FOXP3 forkhead box P3
IL2 interleukin 2
KRAS Kirsten rat sarcoma viral oncogene homolog
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
PDCD1 programmed cell death 1
PEX3 peroxisomal biogenesis factor 3
PI16 peptidase inhibitor 16
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
SETD5 SET domain containing 5
SYTL1 synaptotagmin-like 1
TGFB1 transforming growth factor, beta 1
TXNIP thioredoxin interacting protein
WDR37 WD repeat domain 37