increased pre-b cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater number of progenitor cells that form the B cell component of the immune system (Mammalian Phenotype Ontology, MP_0003132)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003132
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Genes

23 gene mutations causing the increased pre-b cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BCL2 B-cell CLL/lymphoma 2
BLNK B-cell linker
BMF Bcl2 modifying factor
CD69 CD69 molecule
CD72 CD72 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDH17 cadherin 17, LI cadherin (liver-intestine)
ESR2 estrogen receptor 2 (ER beta)
FES FES proto-oncogene, tyrosine kinase
FSHR follicle stimulating hormone receptor
IGKC immunoglobulin kappa constant
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL2 interleukin 2
MTSS1 metastasis suppressor 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PNP purine nucleoside phosphorylase
PTPN2 protein tyrosine phosphatase, non-receptor type 2
SH3BP2 SH3-domain binding protein 2
SIGLEC10 sialic acid binding Ig-like lectin 10
SSBP2 single-stranded DNA binding protein 2
VPREB1 pre-B lymphocyte 1