increased plasmacytoid dendritic cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater number of phagocytic dendritic cells that are morphologically similar to plasma cells, but do not express B lineage markers, and produce large amounts of alpha/beta interferons (IFN-/) in response to viral and bacterial stimuli (Mammalian Phenotype Ontology, MP_0008524)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008524
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Genes

3 gene mutations causing the increased plasmacytoid dendritic cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BCL3 B-cell CLL/lymphoma 3
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
PTPRC protein tyrosine phosphatase, receptor type, C