increased pituitary adenoma incidence Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than the expected number of benign neoplasms of the pituitary, occurring in a specific population in a given time period (Mammalian Phenotype Ontology, MP_0002041)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002041
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Genes

13 gene mutations causing the increased pituitary adenoma incidence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AIP aryl hydrocarbon receptor interacting protein
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
DRD2 dopamine receptor D2
FOXO3 forkhead box O3
HELQ helicase, POLQ-like
MEN1 multiple endocrine neoplasia I
POMC proopiomelanocortin
PRDM2 PR domain containing 2, with ZNF domain
PRL prolactin
RB1 retinoblastoma 1
RINT1 RAD50 interactor 1
THRB thyroid hormone receptor, beta